STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
NCED29-cis-epoxycarotenoid dioxygenase NCED2, chloroplastic; Has a 11,12(11',12') 9-cis epoxycarotenoid cleavage activity. Catalyzes the first step of abscisic-acid (ABA) biosynthesis from carotenoids; Belongs to the carotenoid oxygenase family. (581 aa)    
Predicted Functional Partners:
NSY
Neoxanthin synthase, chloroplastic; Involved in the synthesis of neoxanthin, the last product of carotenoid synthesis and a precursor of abscisic acid. Involved in the beta-carotene biosynthesis ; Belongs to the lycopene cyclase family.
     
 0.971
A0A3Q7G427
Uncharacterized protein.
     
 0.925
A0A3Q7G430
Uncharacterized protein.
     
 0.919
ZEP
Zeaxanthin epoxidase, chloroplastic; Converts zeaxanthin into antheraxanthin and subsequently violaxanthin. Involved in the epoxidation of zeaxanthin. Plays an important role in resistance to stresses, seed development and dormancy.
   
  
 0.733
TAO2
Uncharacterized protein.
      
 0.717
TAO3
Uncharacterized protein.
      
 0.717
CYP707A1
Abscisic acid 8'-hydroxylase CYP707A1; Involved in the oxidative degradation of abscisic acid, especially in pollinated ovaries; Belongs to the cytochrome P450 family.
      
 0.716
CYP707A2
Abscisic acid 8'-hydroxylase CYP707A2; Negative regulator of fruit ripening involved in the oxidative degradation of abscisic acid (ABA).
      
 0.715
ZDS
Zeta-carotene desaturase; Catalyzes the conversion of zeta-carotene to lycopene via the intermediary of neurosporene. It carries out two consecutive desaturations (introduction of double bonds) at positions C-7 and C-7'.
      
 0.711
CRTISO
Prolycopene isomerase, chloroplastic; Carotene cis-trans-isomerase that converts 7,9,9'-tri-cis- neurosporene to 9'-cis-neurosporene and 7,9,9',7'-tetra-cis-lycopene (also known as prolycopene) into all-trans-lycopene. Isomerization requires redox-active components, suggesting that isomerization is achieved by a reversible redox reaction acting at specific double bonds. Isomerizes adjacent cis-double bonds at C7 and C9 pairwise into the trans-configuration, but is incapable of isomerizing single cis- double bonds at C9 and C9'.
     
 0.708
Your Current Organism:
Solanum lycopersicum
NCBI taxonomy Id: 4081
Other names: Lycopersicon esculentum, Lycopersicon esculentum Mill., Lycopersicon esculentum var. esculentum, S. lycopersicum, Solanum esculentum, Solanum esculentum Dunal, Solanum lycopersicum L., Solanum lycopersicum var. humboldtii, tomato
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