Co-purification, co-crystallization, Yeast2Hybrid, Genetic Interactions, etc ... as imported from primary sources.
Groups of genes that are frequently observed in each other's genomic neighborhood.
Known metabolic pathways, protein complexes, signal transduction pathways, etc ... from curated databases.
Genes that are sometimes fused into single open reading frames.
STRING allows inspection of the interaction evidence for any given network. Choose any of the viewers above (disabled if not applicable in your network).
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
colored nodes: query proteins and first shell of interactors
white nodes: second shell of interactors
empty nodes: proteins of unknown 3D structure
filled nodes: some 3D structure is known or predicted
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding each other.
from curated databases
Uncharacterized protein; Nucleotide binding site-leucine rich repeat protein ; Belongs to the disease resistance NB-LRR family (1005 aa)
Predicted Functional Partners:
Uncharacterized protein; NAD(P)-binding Rossmann-fold superfamily protein (308 aa)
ABC transporter family protein (705 aa)
2-methylene-furan-3-one reductase; Enone oxidoreductase involved in the biosynthesis of 4- hydroxy-2,5-dimethyl-3(2H)-furanone (HDMF or furaneol). Can use both NADH and NADPH as the electron donor (388 aa)
Your Current Organism:
NCBI taxonomy Id: 4081 Other names: Lycopersicon esculentum, Lycopersicon esculentum Mill., Lycopersicon esculentum var. esculentum, S. lycopersicum, Solanum esculentum, Solanum esculentum Dunal, Solanum lycopersicum, Solanum lycopersicum L., tomato