Genes that are sometimes fused into single open reading frames.
STRING allows inspection of the interaction evidence for any given network. Choose any of the viewers above (disabled if not applicable in your network).
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
colored nodes: query proteins and first shell of interactors
white nodes: second shell of interactors
empty nodes: proteins of unknown 3D structure
filled nodes: some 3D structure is known or predicted
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding each other.
from curated databases
Uncharacterized protein (932 aa)
Predicted Functional Partners:
DNA polymerase alpha catalytic subunit (1561 aa)
DNA polymerase II subunit 2 ; Participates in DNA repair and in chromosomal DNA replication (529 aa)
Uncharacterized protein (175 aa)
DNA helicase (831 aa)
DNA polymerase alpha subunit B ; May play an essential role at the early stage of chromosomal DNA replication by coupling the polymerase alpha/primase complex to the cellular replication machinery (617 aa)
DNA primase (454 aa)
DNA primase large subunit ; DNA primase is the polymerase that synthesizes small RNA primers for the Okazaki fragments made during discontinuous DNA replication (459 aa)