STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
4CL14-coumarate--CoA ligase 1; Belongs to the ATP-dependent AMP-binding enzyme family. (547 aa)    
Predicted Functional Partners:
CCOAOMT1
Caffeoyl-CoA O-methyltransferase 1; Methylates caffeoyl-CoA to feruloyl-CoA and 5- hydroxyferuloyl-CoA to sinapoyl-CoA. Plays a role in the synthesis of feruloylated polysaccharides. Involved in the reinforcement of the plant cell wall. Also involved in the responding to wounding or pathogen challenge by the increased formation of cell wall-bound ferulic acid polymers; Belongs to the class I-like SAM-binding methyltransferase superfamily. Cation-dependent O-methyltransferase family. CCoAMT subfamily.
   
 0.805
LOC107760944
Putative acyl-activating enzyme 19 isoform X1.
 
0.783
LOC107807467
Putative acyl-activating enzyme 19 isoform X1.
 
0.783
CCOAOMT5
Caffeoyl-CoA O-methyltransferase 5; Methylates caffeoyl-CoA to feruloyl-CoA and 5- hydroxyferuloyl-CoA to sinapoyl-CoA. Plays a role in the synthesis of feruloylated polysaccharides. Involved in the reinforcement of the plant cell wall. Also involved in the responding to wounding or pathogen challenge by the increased formation of cell wall-bound ferulic acid polymers. Methylates 5-hydroxyferulolyl-CoA more efficiently than caffeoyl-CoA; Belongs to the class I-like SAM-binding methyltransferase superfamily. Cation-dependent O-methyltransferase family. CCoAMT subfamily.
   
 0.765
CCOAOMT2
Caffeoyl-CoA O-methyltransferase 2; Methylates caffeoyl-CoA to feruloyl-CoA and 5- hydroxyferuloyl-CoA to sinapoyl-CoA. Plays a role in the synthesis of feruloylated polysaccharides. Involved in the reinforcement of the plant cell wall. Also involved in the responding to wounding or pathogen challenge by the increased formation of cell wall-bound ferulic acid polymers. Methylates 5-hydroxyferulolyl-CoA more efficiently than caffeoyl-CoA; Belongs to the class I-like SAM-binding methyltransferase superfamily. Cation-dependent O-methyltransferase family. CCoAMT subfamily.
   
 0.719
LOC107785450
caffeoyl-CoA O-methyltransferase 1.
   
 0.708
LOC107789450
Probable cinnamyl alcohol dehydrogenase 1.
   
 
 0.706
LOC107760089
Probable beta-1,4-xylosyltransferase IRX10L; Belongs to the glycosyltransferase 47 family.
      
 0.700
LOC107764680
Glycosyltransferases; Involved in the synthesis of glucuronoxylan hemicellulose in secondary cell walls; Belongs to the glycosyltransferase 43 family.
   
  
 0.698
pal4
Phenylalanine ammonia-lyase.
  
  
 0.692
Your Current Organism:
Nicotiana tabacum
NCBI taxonomy Id: 4097
Other names: American tobacco, N. tabacum, Nicotiana tabacum L., common tobacco, tobacco
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