node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
Mlab_0455 | Mlab_0456 | Mlab_0455 | Mlab_0456 | Hypothetical protein. | Protein of unknown function DUF127; Specifically catalyzes the AdoMet-dependent 2'-O-ribose methylation of cytidine at position 56 in tRNAs; Belongs to the aTrm56 family. | 0.798 |
Mlab_0455 | Mlab_0457 | Mlab_0455 | Mlab_0457 | Hypothetical protein. | PFAM: protein of unknown function DUF201. | 0.798 |
Mlab_0455 | Mlab_0459 | Mlab_0455 | Mlab_0459 | Hypothetical protein. | TIGRFAM: metal dependent phophohydrolase; PFAM: metal-dependent phosphohydrolase, HD sub domain; SMART: metal-dependent phosphohydrolase, HD region. | 0.796 |
Mlab_0455 | tfe | Mlab_0455 | Mlab_0458 | Hypothetical protein. | Transcription factor TFIIE, alpha subunit; Transcription factor that plays a role in the activation of archaeal genes transcribed by RNA polymerase. Facilitates transcription initiation by enhancing TATA-box recognition by TATA-box-binding protein (Tbp), and transcription factor B (Tfb) and RNA polymerase recruitment. Not absolutely required for transcription in vitro, but particularly important in cases where Tbp or Tfb function is not optimal. It dynamically alters the nucleic acid-binding properties of RNA polymerases by stabilizing the initiation complex and destabilizing elongatio [...] | 0.796 |
Mlab_0456 | Mlab_0455 | Mlab_0456 | Mlab_0455 | Protein of unknown function DUF127; Specifically catalyzes the AdoMet-dependent 2'-O-ribose methylation of cytidine at position 56 in tRNAs; Belongs to the aTrm56 family. | Hypothetical protein. | 0.798 |
Mlab_0456 | Mlab_0457 | Mlab_0456 | Mlab_0457 | Protein of unknown function DUF127; Specifically catalyzes the AdoMet-dependent 2'-O-ribose methylation of cytidine at position 56 in tRNAs; Belongs to the aTrm56 family. | PFAM: protein of unknown function DUF201. | 0.849 |
Mlab_0456 | Mlab_0459 | Mlab_0456 | Mlab_0459 | Protein of unknown function DUF127; Specifically catalyzes the AdoMet-dependent 2'-O-ribose methylation of cytidine at position 56 in tRNAs; Belongs to the aTrm56 family. | TIGRFAM: metal dependent phophohydrolase; PFAM: metal-dependent phosphohydrolase, HD sub domain; SMART: metal-dependent phosphohydrolase, HD region. | 0.987 |
Mlab_0456 | Mlab_1173 | Mlab_0456 | Mlab_1173 | Protein of unknown function DUF127; Specifically catalyzes the AdoMet-dependent 2'-O-ribose methylation of cytidine at position 56 in tRNAs; Belongs to the aTrm56 family. | Transcriptional regulator, XRE family; PFAM: helix-turn-helix domain protein. | 0.652 |
Mlab_0456 | Mlab_1348 | Mlab_0456 | Mlab_1348 | Protein of unknown function DUF127; Specifically catalyzes the AdoMet-dependent 2'-O-ribose methylation of cytidine at position 56 in tRNAs; Belongs to the aTrm56 family. | PFAM: PUA domain containing protein. | 0.691 |
Mlab_0456 | nac | Mlab_0456 | Mlab_1349 | Protein of unknown function DUF127; Specifically catalyzes the AdoMet-dependent 2'-O-ribose methylation of cytidine at position 56 in tRNAs; Belongs to the aTrm56 family. | Nascent polypeptide associated complex NAC; Contacts the emerging nascent chain on the ribosome. Belongs to the NAC-alpha family. | 0.671 |
Mlab_0456 | pfdB | Mlab_0456 | Mlab_1336 | Protein of unknown function DUF127; Specifically catalyzes the AdoMet-dependent 2'-O-ribose methylation of cytidine at position 56 in tRNAs; Belongs to the aTrm56 family. | Prefoldin, beta subunit; Molecular chaperone capable of stabilizing a range of proteins. Seems to fulfill an ATP-independent, HSP70-like function in archaeal de novo protein folding. | 0.641 |
Mlab_0456 | ribK | Mlab_0456 | Mlab_1629 | Protein of unknown function DUF127; Specifically catalyzes the AdoMet-dependent 2'-O-ribose methylation of cytidine at position 56 in tRNAs; Belongs to the aTrm56 family. | Protein of unknown function DUF120; Catalyzes the CTP-dependent phosphorylation of riboflavin (vitamin B2) to form flavin mononucleotide (FMN); Belongs to the archaeal riboflavin kinase family. | 0.657 |
Mlab_0456 | tfe | Mlab_0456 | Mlab_0458 | Protein of unknown function DUF127; Specifically catalyzes the AdoMet-dependent 2'-O-ribose methylation of cytidine at position 56 in tRNAs; Belongs to the aTrm56 family. | Transcription factor TFIIE, alpha subunit; Transcription factor that plays a role in the activation of archaeal genes transcribed by RNA polymerase. Facilitates transcription initiation by enhancing TATA-box recognition by TATA-box-binding protein (Tbp), and transcription factor B (Tfb) and RNA polymerase recruitment. Not absolutely required for transcription in vitro, but particularly important in cases where Tbp or Tfb function is not optimal. It dynamically alters the nucleic acid-binding properties of RNA polymerases by stabilizing the initiation complex and destabilizing elongatio [...] | 0.893 |
Mlab_0456 | tiaS | Mlab_0456 | Mlab_0159 | Protein of unknown function DUF127; Specifically catalyzes the AdoMet-dependent 2'-O-ribose methylation of cytidine at position 56 in tRNAs; Belongs to the aTrm56 family. | Domain of unknown function DUF1743; ATP-dependent agmatine transferase that catalyzes the formation of 2-agmatinylcytidine (agm2C) at the wobble position (C34) of tRNA(Ile2), converting the codon specificity from AUG to AUA. | 0.650 |
Mlab_0457 | Mlab_0455 | Mlab_0457 | Mlab_0455 | PFAM: protein of unknown function DUF201. | Hypothetical protein. | 0.798 |
Mlab_0457 | Mlab_0456 | Mlab_0457 | Mlab_0456 | PFAM: protein of unknown function DUF201. | Protein of unknown function DUF127; Specifically catalyzes the AdoMet-dependent 2'-O-ribose methylation of cytidine at position 56 in tRNAs; Belongs to the aTrm56 family. | 0.849 |
Mlab_0457 | Mlab_0459 | Mlab_0457 | Mlab_0459 | PFAM: protein of unknown function DUF201. | TIGRFAM: metal dependent phophohydrolase; PFAM: metal-dependent phosphohydrolase, HD sub domain; SMART: metal-dependent phosphohydrolase, HD region. | 0.818 |
Mlab_0457 | tfe | Mlab_0457 | Mlab_0458 | PFAM: protein of unknown function DUF201. | Transcription factor TFIIE, alpha subunit; Transcription factor that plays a role in the activation of archaeal genes transcribed by RNA polymerase. Facilitates transcription initiation by enhancing TATA-box recognition by TATA-box-binding protein (Tbp), and transcription factor B (Tfb) and RNA polymerase recruitment. Not absolutely required for transcription in vitro, but particularly important in cases where Tbp or Tfb function is not optimal. It dynamically alters the nucleic acid-binding properties of RNA polymerases by stabilizing the initiation complex and destabilizing elongatio [...] | 0.818 |
Mlab_0459 | Mlab_0455 | Mlab_0459 | Mlab_0455 | TIGRFAM: metal dependent phophohydrolase; PFAM: metal-dependent phosphohydrolase, HD sub domain; SMART: metal-dependent phosphohydrolase, HD region. | Hypothetical protein. | 0.796 |
Mlab_0459 | Mlab_0456 | Mlab_0459 | Mlab_0456 | TIGRFAM: metal dependent phophohydrolase; PFAM: metal-dependent phosphohydrolase, HD sub domain; SMART: metal-dependent phosphohydrolase, HD region. | Protein of unknown function DUF127; Specifically catalyzes the AdoMet-dependent 2'-O-ribose methylation of cytidine at position 56 in tRNAs; Belongs to the aTrm56 family. | 0.987 |