STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
psmBProteasome endopeptidase complex; Component of the proteasome core, a large protease complex with broad specificity involved in protein degradation. (212 aa)    
Predicted Functional Partners:
psmA
Proteasome endopeptidase complex; Component of the proteasome core, a large protease complex with broad specificity involved in protein degradation.
 
 
0.974
Mlab_0407
Hypothetical protein.
   
 0.931
pan
26S proteasome subunit P45 family; ATPase which is responsible for recognizing, binding, unfolding and translocation of substrate proteins into the archaeal 20S proteasome core particle. Is essential for opening the gate of the 20S proteasome via an interaction with its C-terminus, thereby allowing substrate entry and access to the site of proteolysis. Thus, the C- termini of the proteasomal ATPase function like a 'key in a lock' to induce gate opening and therefore regulate proteolysis. Unfolding activity requires energy from ATP hydrolysis, whereas ATP binding alone promotes ATPase-2 [...]
 
 0.930
Mlab_0867
SMART: AAA ATPase; TIGRFAM: 26S proteasome subunit P45 family; PFAM: AAA ATPase, central domain protein; Belongs to the AAA ATPase family.
  
 0.919
rpl40e
PFAM: Ribosomal protein L40e; Belongs to the eukaryotic ribosomal protein eL40 family.
   
 0.888
Mlab_1017
PFAM: AAA ATPase, central domain protein; SMART: AAA ATPase; Belongs to the AAA ATPase family.
  
 0.843
Mlab_1014
PFAM: beta-lactamase domain protein; KH, type 1, domain protein; RNA-metabolising metallo-beta-lactamase; SMART: KH domain protein.
     
 0.830
Mlab_0625
SMART: AAA ATPase; TIGRFAM: AAA family ATPase, CDC48 subfamily; PFAM: AAA ATPase VAT domain protein domain protein; AAA ATPase, central domain protein; ATPase associated with various cellular activities, AAA_5.
 
 0.737
Mlab_1124
SMART: AAA ATPase; TIGRFAM: AAA family ATPase, CDC48 subfamily; PFAM: AAA ATPase VAT domain protein domain protein; AAA ATPase, central domain protein; cell division protein 48, CDC48, domain 2.
 
 0.737
Mlab_0771
PFAM: chaperonin Cpn60/TCP-1; Belongs to the TCP-1 chaperonin family.
 
 
 0.603
Your Current Organism:
Methanocorpusculum labreanum
NCBI taxonomy Id: 410358
Other names: M. labreanum Z, Methanocorpusculum labreanum Z, Methanocorpusculum labreanum str. Z, Methanocorpusculum labreanum strain Z
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.