STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
polCDNA polymerase II, large subunit DP2; Possesses two activities: a DNA synthesis (polymerase) and an exonucleolytic activity that degrades single-stranded DNA in the 3'- to 5'-direction. Has a template-primer preference which is characteristic of a replicative DNA polymerase (By similarity). (1141 aa)    
Predicted Functional Partners:
polB
DNA-directed DNA polymerase; Possesses two activities: a DNA synthesis (polymerase) and an exonucleolytic activity that degrades single-stranded DNA in the 3' to 5' direction. Has a template-primer preference which is characteristic of a replicative DNA polymerase; Belongs to the DNA polymerase delta/II small subunit family.
 
 
 
 0.968
pcn
Monomeric archaeal DNA polymerase sliding clamp; Sliding clamp subunit that acts as a moving platform for DNA processing. Responsible for tethering the catalytic subunit of DNA polymerase and other proteins to DNA during high-speed replication. Belongs to the PCNA family.
 
 
 
 0.954
Mlab_1700
PFAM: PBS lyase HEAT domain protein repeat-containing protein.
       0.779
Mlab_1701
PFAM: MscS Mechanosensitive ion channel.
       0.773
Mlab_1702
PFAM: Protein of unknown function DUF432.
       0.773
Mlab_0289
PFAM: phosphoesterase, RecJ domain protein; phosphoesterase, DHHA1.
 
     0.676
Mlab_1347
PFAM: phosphoesterase, RecJ domain protein; phosphoesterase, DHHA1.
 
     0.675
Mlab_1297
PFAM: protein of unknown function DUF75.
  
     0.672
nac
Nascent polypeptide associated complex NAC; Contacts the emerging nascent chain on the ribosome. Belongs to the NAC-alpha family.
 
     0.671
Mlab_0774
Nucleic acid-binding protein consists of a PIN domain and a Zn-ribbon module-like protein.
 
     0.665
Your Current Organism:
Methanocorpusculum labreanum
NCBI taxonomy Id: 410358
Other names: M. labreanum Z, Methanocorpusculum labreanum Z, Methanocorpusculum labreanum str. Z, Methanocorpusculum labreanum strain Z
Server load: medium (46%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.