node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
Pcal_0567 | egsA | Pcal_0567 | Pcal_0566 | KEGG: pai:PAE1683 hypothetical protein. | 3-dehydroquinate synthase; Catalyzes the NAD(P)H-dependent reduction of dihydroxyacetonephosphate (DHAP or glycerone phosphate) to glycerol 1- phosphate (G1P). The G1P thus generated is used as the glycerophosphate backbone of phospholipids in the cellular membranes of Archaea. | 0.812 |
Pcal_0567 | tpiA | Pcal_0567 | Pcal_0817 | KEGG: pai:PAE1683 hypothetical protein. | Triosephosphate isomerase; Involved in the gluconeogenesis. Catalyzes stereospecifically the conversion of dihydroxyacetone phosphate (DHAP) to D- glyceraldehyde-3-phosphate (G3P); Belongs to the triosephosphate isomerase family. | 0.481 |
Pcal_0744 | Pcal_1072 | Pcal_0744 | Pcal_1072 | PFAM: D-isomer specific 2-hydroxyacid dehydrogenase, catalytic region; D-isomer specific 2-hydroxyacid dehydrogenase, NAD-binding; KEGG: pai:PAE1175 2-hydroxyacid dehydrogenase. | PFAM: class II aldolase/adducin family protein; KEGG: pai:PAE2158 fuculose-1-phosphate aldolase. | 0.425 |
Pcal_0744 | Pcal_1387 | Pcal_0744 | Pcal_1387 | PFAM: D-isomer specific 2-hydroxyacid dehydrogenase, catalytic region; D-isomer specific 2-hydroxyacid dehydrogenase, NAD-binding; KEGG: pai:PAE1175 2-hydroxyacid dehydrogenase. | PFAM: aldehyde dehydrogenase; KEGG: sto:ST0064 glyceraldehyde-3-phosphate dehydrogenase, NADP dependent. | 0.446 |
Pcal_0744 | egsA | Pcal_0744 | Pcal_0566 | PFAM: D-isomer specific 2-hydroxyacid dehydrogenase, catalytic region; D-isomer specific 2-hydroxyacid dehydrogenase, NAD-binding; KEGG: pai:PAE1175 2-hydroxyacid dehydrogenase. | 3-dehydroquinate synthase; Catalyzes the NAD(P)H-dependent reduction of dihydroxyacetonephosphate (DHAP or glycerone phosphate) to glycerol 1- phosphate (G1P). The G1P thus generated is used as the glycerophosphate backbone of phospholipids in the cellular membranes of Archaea. | 0.469 |
Pcal_0744 | tpiA | Pcal_0744 | Pcal_0817 | PFAM: D-isomer specific 2-hydroxyacid dehydrogenase, catalytic region; D-isomer specific 2-hydroxyacid dehydrogenase, NAD-binding; KEGG: pai:PAE1175 2-hydroxyacid dehydrogenase. | Triosephosphate isomerase; Involved in the gluconeogenesis. Catalyzes stereospecifically the conversion of dihydroxyacetone phosphate (DHAP) to D- glyceraldehyde-3-phosphate (G3P); Belongs to the triosephosphate isomerase family. | 0.401 |
Pcal_0891 | aroD | Pcal_0891 | Pcal_0911 | 3-deoxy-D-arabinoheptulosonate-7-phosphate synthase; TIGRFAM: phospho-2-dehydro-3-deoxyheptonate aldolase; PFAM: DAHP synthetase I/KDSA; KEGG: pai:PAE1932 phospho-2-dehydro-3-deoxyheptonate aldolase. | Chorismate mutase / 3-dehydroquinate dehydratase; Involved in the third step of the chorismate pathway, which leads to the biosynthesis of aromatic amino acids. Catalyzes the cis- dehydration of 3-dehydroquinate (DHQ) and introduces the first double bond of the aromatic ring to yield 3-dehydroshikimate. Belongs to the type-I 3-dehydroquinase family. | 0.675 |
Pcal_0891 | egsA | Pcal_0891 | Pcal_0566 | 3-deoxy-D-arabinoheptulosonate-7-phosphate synthase; TIGRFAM: phospho-2-dehydro-3-deoxyheptonate aldolase; PFAM: DAHP synthetase I/KDSA; KEGG: pai:PAE1932 phospho-2-dehydro-3-deoxyheptonate aldolase. | 3-dehydroquinate synthase; Catalyzes the NAD(P)H-dependent reduction of dihydroxyacetonephosphate (DHAP or glycerone phosphate) to glycerol 1- phosphate (G1P). The G1P thus generated is used as the glycerophosphate backbone of phospholipids in the cellular membranes of Archaea. | 0.499 |
Pcal_0985 | egsA | Pcal_0985 | Pcal_0566 | Geranylgeranylglyceryl phosphate synthase; Prenyltransferase that catalyzes the transfer of the geranylgeranyl moiety of geranylgeranyl diphosphate (GGPP) to the C3 hydroxyl of sn-glycerol-1-phosphate (G1P). This reaction is the first ether-bond-formation step in the biosynthesis of archaeal membrane lipids. | 3-dehydroquinate synthase; Catalyzes the NAD(P)H-dependent reduction of dihydroxyacetonephosphate (DHAP or glycerone phosphate) to glycerol 1- phosphate (G1P). The G1P thus generated is used as the glycerophosphate backbone of phospholipids in the cellular membranes of Archaea. | 0.933 |
Pcal_1072 | Pcal_0744 | Pcal_1072 | Pcal_0744 | PFAM: class II aldolase/adducin family protein; KEGG: pai:PAE2158 fuculose-1-phosphate aldolase. | PFAM: D-isomer specific 2-hydroxyacid dehydrogenase, catalytic region; D-isomer specific 2-hydroxyacid dehydrogenase, NAD-binding; KEGG: pai:PAE1175 2-hydroxyacid dehydrogenase. | 0.425 |
Pcal_1072 | Pcal_1387 | Pcal_1072 | Pcal_1387 | PFAM: class II aldolase/adducin family protein; KEGG: pai:PAE2158 fuculose-1-phosphate aldolase. | PFAM: aldehyde dehydrogenase; KEGG: sto:ST0064 glyceraldehyde-3-phosphate dehydrogenase, NADP dependent. | 0.487 |
Pcal_1072 | egsA | Pcal_1072 | Pcal_0566 | PFAM: class II aldolase/adducin family protein; KEGG: pai:PAE2158 fuculose-1-phosphate aldolase. | 3-dehydroquinate synthase; Catalyzes the NAD(P)H-dependent reduction of dihydroxyacetonephosphate (DHAP or glycerone phosphate) to glycerol 1- phosphate (G1P). The G1P thus generated is used as the glycerophosphate backbone of phospholipids in the cellular membranes of Archaea. | 0.719 |
Pcal_1072 | tpiA | Pcal_1072 | Pcal_0817 | PFAM: class II aldolase/adducin family protein; KEGG: pai:PAE2158 fuculose-1-phosphate aldolase. | Triosephosphate isomerase; Involved in the gluconeogenesis. Catalyzes stereospecifically the conversion of dihydroxyacetone phosphate (DHAP) to D- glyceraldehyde-3-phosphate (G3P); Belongs to the triosephosphate isomerase family. | 0.950 |
Pcal_1387 | Pcal_0744 | Pcal_1387 | Pcal_0744 | PFAM: aldehyde dehydrogenase; KEGG: sto:ST0064 glyceraldehyde-3-phosphate dehydrogenase, NADP dependent. | PFAM: D-isomer specific 2-hydroxyacid dehydrogenase, catalytic region; D-isomer specific 2-hydroxyacid dehydrogenase, NAD-binding; KEGG: pai:PAE1175 2-hydroxyacid dehydrogenase. | 0.446 |
Pcal_1387 | Pcal_1072 | Pcal_1387 | Pcal_1072 | PFAM: aldehyde dehydrogenase; KEGG: sto:ST0064 glyceraldehyde-3-phosphate dehydrogenase, NADP dependent. | PFAM: class II aldolase/adducin family protein; KEGG: pai:PAE2158 fuculose-1-phosphate aldolase. | 0.487 |
Pcal_1387 | egsA | Pcal_1387 | Pcal_0566 | PFAM: aldehyde dehydrogenase; KEGG: sto:ST0064 glyceraldehyde-3-phosphate dehydrogenase, NADP dependent. | 3-dehydroquinate synthase; Catalyzes the NAD(P)H-dependent reduction of dihydroxyacetonephosphate (DHAP or glycerone phosphate) to glycerol 1- phosphate (G1P). The G1P thus generated is used as the glycerophosphate backbone of phospholipids in the cellular membranes of Archaea. | 0.535 |
Pcal_1387 | tpiA | Pcal_1387 | Pcal_0817 | PFAM: aldehyde dehydrogenase; KEGG: sto:ST0064 glyceraldehyde-3-phosphate dehydrogenase, NADP dependent. | Triosephosphate isomerase; Involved in the gluconeogenesis. Catalyzes stereospecifically the conversion of dihydroxyacetone phosphate (DHAP) to D- glyceraldehyde-3-phosphate (G3P); Belongs to the triosephosphate isomerase family. | 0.538 |
Pcal_2112 | egsA | Pcal_2112 | Pcal_0566 | Carbohydrate ABC transporter substrate-binding protein, CUT1 family; PFAM: extracellular solute-binding protein, family 1; KEGG: pai:PAE0689 multiple sugar binding protein; TC 3.A.1.1.-. | 3-dehydroquinate synthase; Catalyzes the NAD(P)H-dependent reduction of dihydroxyacetonephosphate (DHAP or glycerone phosphate) to glycerol 1- phosphate (G1P). The G1P thus generated is used as the glycerophosphate backbone of phospholipids in the cellular membranes of Archaea. | 0.512 |
aroD | Pcal_0891 | Pcal_0911 | Pcal_0891 | Chorismate mutase / 3-dehydroquinate dehydratase; Involved in the third step of the chorismate pathway, which leads to the biosynthesis of aromatic amino acids. Catalyzes the cis- dehydration of 3-dehydroquinate (DHQ) and introduces the first double bond of the aromatic ring to yield 3-dehydroshikimate. Belongs to the type-I 3-dehydroquinase family. | 3-deoxy-D-arabinoheptulosonate-7-phosphate synthase; TIGRFAM: phospho-2-dehydro-3-deoxyheptonate aldolase; PFAM: DAHP synthetase I/KDSA; KEGG: pai:PAE1932 phospho-2-dehydro-3-deoxyheptonate aldolase. | 0.675 |
aroD | egsA | Pcal_0911 | Pcal_0566 | Chorismate mutase / 3-dehydroquinate dehydratase; Involved in the third step of the chorismate pathway, which leads to the biosynthesis of aromatic amino acids. Catalyzes the cis- dehydration of 3-dehydroquinate (DHQ) and introduces the first double bond of the aromatic ring to yield 3-dehydroshikimate. Belongs to the type-I 3-dehydroquinase family. | 3-dehydroquinate synthase; Catalyzes the NAD(P)H-dependent reduction of dihydroxyacetonephosphate (DHAP or glycerone phosphate) to glycerol 1- phosphate (G1P). The G1P thus generated is used as the glycerophosphate backbone of phospholipids in the cellular membranes of Archaea. | 0.518 |