STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
Pcal_0791Transcriptional regulator, XRE family; PFAM: helix-turn-helix domain protein; KEGG: sto:ST2084 hypothetical transcriptional regulator. (528 aa)    
Predicted Functional Partners:
Pcal_0790
PFAM: AzlC family protein; KEGG: csa:Csal_0390 AzlC-like protein.
 
  
 0.889
Pcal_0792
PFAM: transcriptional regulator PadR family protein; KEGG: pai:PAE1218 hypothetical protein.
 
  
 0.741
Pcal_0789
KEGG: sto:ST1576 hypothetical protein.
       0.730
nadE
NH(3)-dependent NAD(+) synthetase; Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses ammonia as a nitrogen source.
     
 0.688
Pcal_0788
Conserved hypothetical protein; KEGG: pai:PAE2605 conserved within P.aerophilum.
       0.656
guaA
GMP synthase (glutamine-hydrolyzing); Catalyzes the synthesis of GMP from XMP.
     
 0.570
Pcal_1967
PFAM: Resolvase, N-terminal domain; KEGG: pai:PAE3513 resolvase, conjectural.
 
  
 0.522
Pcal_0545
PFAM: protein of unknown function DUF224, cysteine-rich region domain protein; KEGG: pai:PAE1762 iron-sulfur binding reductase, probable.
 
 
 
 0.464
Pcal_0576
DNA-cytosine methyltransferase; KEGG: pai:PAE1659 C-5 cytosine-specific DNA methylase; TIGRFAM: DNA-cytosine methyltransferase; PFAM: C-5 cytosine-specific DNA methylase; Belongs to the class I-like SAM-binding methyltransferase superfamily. C5-methyltransferase family.
     
 0.460
Pcal_0120
PFAM: extracellular solute-binding protein, family 1; KEGG: pai:PAE0953 putrescine/spermidine binding protein, conjectural.
     
 0.459
Your Current Organism:
Pyrobaculum calidifontis
NCBI taxonomy Id: 410359
Other names: P. calidifontis JCM 11548, Pyrobaculum calidifontis JCM 11548, Pyrobaculum calidifontis VA1, Pyrobaculum calidifontis str. JCM 11548, Pyrobaculum calidifontis strain JCM 11548
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