STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
dcddCTP deaminase; Catalyzes the deamination of dCTP to dUTP. (176 aa)    
Predicted Functional Partners:
pyrG
CTP synthase; Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen. Regulates intracellular CTP levels through interactions with the four ribonucleotide triphosphates.
  
 
 0.943
Pcal_0523
PFAM: nucleoside diphosphate kinase; KEGG: pai:PAE1561 nucleoside diphosphate kinase.
  
 
 0.939
Pcal_0237
PFAM: NUDIX hydrolase; KEGG: pai:PAE0252 diadenosine 5'5'''-P1,P4-tetraphosphate pyrophosphohydrolase (MutT/NUDIX family protein).
   
  0.918
Pcal_2125
PFAM: NUDIX hydrolase; KEGG: pai:PAE0714 diadenosine 5'5'''-P1,P4-tetraphosphate pyrophosphohydrolase (MutT/NUDIX family protein).
   
  0.918
guaA
GMP synthase (glutamine-hydrolyzing); Catalyzes the synthesis of GMP from XMP.
  
  
 0.639
Pcal_1022
KEGG: pai:PAE3607 hypothetical protein.
       0.594
Pcal_1023
KEGG: pai:PAE3608 hypothetical protein.
       0.594
tmk
PFAM: thymidylate kinase; KEGG: pai:PAE0964 thymidylate kinase.
  
  
 0.567
pyrE
Orotate phosphoribosyltransferase; Catalyzes the transfer of a ribosyl phosphate group from 5- phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP).
  
 
 0.558
Pcal_1020
KEGG: pai:PAE2010 hypothetical protein.
       0.550
Your Current Organism:
Pyrobaculum calidifontis
NCBI taxonomy Id: 410359
Other names: P. calidifontis JCM 11548, Pyrobaculum calidifontis JCM 11548, Pyrobaculum calidifontis VA1, Pyrobaculum calidifontis str. JCM 11548, Pyrobaculum calidifontis strain JCM 11548
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