STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
cmkTIGRFAM: cytidylate kinase, putative; KEGG: pai:PAE3225 cytidylate kinase (cmk). (184 aa)    
Predicted Functional Partners:
rpl34e
PFAM: Ribosomal protein L34e; KEGG: pai:PAE3224 ribosomal protein L34; Belongs to the eukaryotic ribosomal protein eL34 family.
  
    0.986
rpl4
LSU ribosomal protein L4P; Forms part of the polypeptide exit tunnel.
  
    0.926
truB
tRNA pseudouridine synthase B; Could be responsible for synthesis of pseudouridine from uracil-55 in the psi GC loop of transfer RNAs; Belongs to the pseudouridine synthase TruB family. Type 2 subfamily.
      0.925
rpl22
LSU ribosomal protein L22P; This protein binds specifically to 23S rRNA. It makes multiple contacts with different domains of the 23S rRNA in the assembled 50S subunit and ribosome.
  
    0.921
rpl14e
KEGG: pai:PAE0862 ribosomal protein L14; Belongs to the eukaryotic ribosomal protein eL14 family.
  
    0.920
Pcal_0523
PFAM: nucleoside diphosphate kinase; KEGG: pai:PAE1561 nucleoside diphosphate kinase.
     
 0.920
Pcal_1797
Ribonucleoside-diphosphate reductase, adenosylcobalamin-dependent; Catalyzes the reduction of ribonucleotides to deoxyribonucleotides. May function to provide a pool of deoxyribonucleotide precursors for DNA repair during oxygen limitation and/or for immediate growth after restoration of oxygen.
 
  
  0.917
rpl24
LSU ribosomal protein L24P; One of two assembly initiator proteins, it binds directly to the 5'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit.
  
    0.916
rpl14
LSU ribosomal protein L14P; Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome; Belongs to the universal ribosomal protein uL14 family.
  
    0.916
rps4e
PFAM: RNA-binding S4 domain protein; Ribosomal protein S4E-like; Ribosomal protein S4E, central; KEGG: pai:PAE3313 ribosomal protein S4; Belongs to the eukaryotic ribosomal protein eS4 family.
  
    0.914
Your Current Organism:
Pyrobaculum calidifontis
NCBI taxonomy Id: 410359
Other names: P. calidifontis JCM 11548, Pyrobaculum calidifontis JCM 11548, Pyrobaculum calidifontis VA1, Pyrobaculum calidifontis str. JCM 11548, Pyrobaculum calidifontis strain JCM 11548
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