STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
Pcal_1546Predicted hydrolase of the metallo-beta-lactamase superfamily; KEGG: pai:PAE3680 hypothetical protein; Belongs to the UPF0282 family. (301 aa)    
Predicted Functional Partners:
Pcal_1545
paREP1; KEGG: pai:PAE0369 paREP1.
       0.773
Pcal_1547
Uncharacterized membrane-associated protein/domain-like protein; KEGG: pai:PAE3650 hypothetical protein.
       0.620
Pcal_2061
PFAM: Protein of unknown function DUF371; KEGG: pai:PAE0628 hypothetical protein.
  
   
 0.595
nep1
Suppressor Mra1; Methyltransferase involved in ribosomal biogenesis. Specifically catalyzes the N1-methylation of the pseudouridine corresponding to position 914 in M.jannaschii 16S rRNA.
 
     0.563
Pcal_1548
PFAM: Protein of unknown function DUF1626; KEGG: pai:PAE0355 hypothetical protein.
       0.508
kptA
Phosphotransferase KptA/Tpt1; Removes the 2'-phosphate from RNA via an intermediate in which the phosphate is ADP-ribosylated by NAD followed by a presumed transesterification to release the RNA and generate ADP-ribose 1''-2''- cyclic phosphate (APPR>P). May function as an ADP-ribosylase.
       0.508
Pcal_0967
PFAM: protein of unknown function DUF72; KEGG: pai:PAE3079 hypothetical protein.
 
     0.507
Pcal_0616
PFAM: AAA ATPase, central domain protein; TIP49-like; SMART: AAA ATPase; KEGG: pai:PAE1693 TBP-interacting protein TIP49.
  
     0.452
Pcal_1120
PFAM: protein of unknown function UPF0153; KEGG: pai:PAE2987 hypothetical protein.
 
     0.436
Pcal_0035
PFAM: AMMECR1 domain protein; KEGG: pai:PAE0830 hypothetical protein.
 
     0.433
Your Current Organism:
Pyrobaculum calidifontis
NCBI taxonomy Id: 410359
Other names: P. calidifontis JCM 11548, Pyrobaculum calidifontis JCM 11548, Pyrobaculum calidifontis VA1, Pyrobaculum calidifontis str. JCM 11548, Pyrobaculum calidifontis strain JCM 11548
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