STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
mdhMalate dehydrogenase (NAD); Catalyzes the reversible oxidation of malate to oxaloacetate. Belongs to the LDH/MDH superfamily. (309 aa)    
Predicted Functional Partners:
Pcal_0154
KEGG: pai:PAE3584 citrate synthase; TIGRFAM: 2-methylcitrate synthase/citrate synthase II; PFAM: Citrate synthase.
  
 0.995
Pcal_0563
KEGG: pai:PAE1689 citrate synthase; TIGRFAM: 2-methylcitrate synthase/citrate synthase II; PFAM: Citrate synthase.
  
 0.995
Pcal_0579
TIGRFAM: isocitrate dehydrogenase, NADP-dependent; PFAM: isocitrate/isopropylmalate dehydrogenase; KEGG: pai:PAE1651 isocitrate dehydrogenase.
  
 
 0.986
Pcal_1059
Fumarase beta subunit; KEGG: pai:PAE2131 fumarate hydratase class I beta subunit; TIGRFAM: hydro-lyases, Fe-S type, tartrate/fumarate subfamily, beta subunit; PFAM: Fe-S type hydro-lyases tartrate/fumarate beta region.
  
 
 0.985
Pcal_1060
Fumarase alpha subunit; TIGRFAM: hydro-lyases, Fe-S type, tartrate/fumarate subfamily, alpha subunit; PFAM: Fe-S type hydro-lyases tartrate/fumarate alpha region; KEGG: pai:PAE2132 fumarate hydratase class I alpha subunit.
  
 
 0.985
Pcal_0564
Malate dehydrogenase (oxaloacetate-decarboxylating); PFAM: malic enzyme domain protein; malic enzyme, NAD-binding; KEGG: pai:PAE1688 malate oxidoreductase (mae).
  
 0.950
Pcal_1223
PFAM: malate synthase; KEGG: pai:PAE1287 malate synthase.
   
 0.947
Pcal_0914
L-aspartate aminotransferase apoenzyme; PFAM: aminotransferase, class I and II; KEGG: pai:PAE1964 aspartate aminotransferase, conjectural.
  
 0.941
Pcal_0962
PFAM: aminotransferase, class I and II; KEGG: pai:PAE2251 aspartate aminotransferase (aspC), conjectural.
  
 0.941
gap
KEGG: pai:PAE1740 glyceraldehyde-3-phosphate dehydrogenase; TIGRFAM: glyceraldehyde-3-phosphate dehydrogenase, type II; PFAM: glyceraldehyde 3-phosphate dehydrogenase; dihydrodipicolinate reductase.
  
 
 0.939
Your Current Organism:
Pyrobaculum calidifontis
NCBI taxonomy Id: 410359
Other names: P. calidifontis JCM 11548, Pyrobaculum calidifontis JCM 11548, Pyrobaculum calidifontis VA1, Pyrobaculum calidifontis str. JCM 11548, Pyrobaculum calidifontis strain JCM 11548
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