node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
Pcal_1440 | Pcal_1458 | Pcal_1440 | Pcal_1458 | PFAM: Uroporphyrin-III C/tetrapyrrole (Corrin/Porphyrin) methyltransferase; KEGG: pai:PAE2573 uroporphyrin-III C-methyltransferase; Belongs to the precorrin methyltransferase family. | PFAM: Uroporphyrinogen III synthase HEM4; KEGG: pai:PAE2594 uroporphyrinogen-III synthase (HemD), conjectural. | 0.951 |
Pcal_1440 | Pcal_1709 | Pcal_1440 | Pcal_1709 | PFAM: Uroporphyrin-III C/tetrapyrrole (Corrin/Porphyrin) methyltransferase; KEGG: pai:PAE2573 uroporphyrin-III C-methyltransferase; Belongs to the precorrin methyltransferase family. | Porphobilinogen synthase; PFAM: delta-aminolevulinic acid dehydratase; KEGG: pai:PAE0583 porphobilinogen synthase (delta-aminolevulinic acid dehydratase); Belongs to the ALAD family. | 0.657 |
Pcal_1440 | Pcal_1710 | Pcal_1440 | Pcal_1710 | PFAM: Uroporphyrin-III C/tetrapyrrole (Corrin/Porphyrin) methyltransferase; KEGG: pai:PAE2573 uroporphyrin-III C-methyltransferase; Belongs to the precorrin methyltransferase family. | TIGRFAM: siroheme synthase; KEGG: pai:PAE0585 siroheme synthesis protein, conjectural. | 0.984 |
Pcal_1440 | Pcal_1712 | Pcal_1440 | Pcal_1712 | PFAM: Uroporphyrin-III C/tetrapyrrole (Corrin/Porphyrin) methyltransferase; KEGG: pai:PAE2573 uroporphyrin-III C-methyltransferase; Belongs to the precorrin methyltransferase family. | PFAM: Uroporphyrinogen III synthase HEM4; KEGG: pai:PAE0589 uroporphyrinogen-III synthase. | 0.933 |
Pcal_1440 | Pcal_1713 | Pcal_1440 | Pcal_1713 | PFAM: Uroporphyrin-III C/tetrapyrrole (Corrin/Porphyrin) methyltransferase; KEGG: pai:PAE2573 uroporphyrin-III C-methyltransferase; Belongs to the precorrin methyltransferase family. | TIGRFAM: uroporphyrin-III C-methyltransferase; PFAM: Uroporphyrin-III C/tetrapyrrole (Corrin/Porphyrin) methyltransferase; KEGG: pai:PAE0590 uroporphyrin-III C-methyltransferase. | 0.917 |
Pcal_1440 | hemA1 | Pcal_1440 | Pcal_1481 | PFAM: Uroporphyrin-III C/tetrapyrrole (Corrin/Porphyrin) methyltransferase; KEGG: pai:PAE2573 uroporphyrin-III C-methyltransferase; Belongs to the precorrin methyltransferase family. | glutamyl-tRNA reductase; Catalyzes the NADPH-dependent reduction of glutamyl-tRNA(Glu) to glutamate 1-semialdehyde (GSA). | 0.492 |
Pcal_1440 | hemA2 | Pcal_1440 | Pcal_2034 | PFAM: Uroporphyrin-III C/tetrapyrrole (Corrin/Porphyrin) methyltransferase; KEGG: pai:PAE2573 uroporphyrin-III C-methyltransferase; Belongs to the precorrin methyltransferase family. | glutamyl-tRNA reductase; Catalyzes the NADPH-dependent reduction of glutamyl-tRNA(Glu) to glutamate 1-semialdehyde (GSA). | 0.492 |
Pcal_1440 | hemC | Pcal_1440 | Pcal_1707 | PFAM: Uroporphyrin-III C/tetrapyrrole (Corrin/Porphyrin) methyltransferase; KEGG: pai:PAE2573 uroporphyrin-III C-methyltransferase; Belongs to the precorrin methyltransferase family. | Porphobilinogen deaminase; Tetrapolymerization of the monopyrrole PBG into the hydroxymethylbilane pre-uroporphyrinogen in several discrete steps. | 0.778 |
Pcal_1458 | Pcal_1440 | Pcal_1458 | Pcal_1440 | PFAM: Uroporphyrinogen III synthase HEM4; KEGG: pai:PAE2594 uroporphyrinogen-III synthase (HemD), conjectural. | PFAM: Uroporphyrin-III C/tetrapyrrole (Corrin/Porphyrin) methyltransferase; KEGG: pai:PAE2573 uroporphyrin-III C-methyltransferase; Belongs to the precorrin methyltransferase family. | 0.951 |
Pcal_1458 | Pcal_1709 | Pcal_1458 | Pcal_1709 | PFAM: Uroporphyrinogen III synthase HEM4; KEGG: pai:PAE2594 uroporphyrinogen-III synthase (HemD), conjectural. | Porphobilinogen synthase; PFAM: delta-aminolevulinic acid dehydratase; KEGG: pai:PAE0583 porphobilinogen synthase (delta-aminolevulinic acid dehydratase); Belongs to the ALAD family. | 0.847 |
Pcal_1458 | Pcal_1710 | Pcal_1458 | Pcal_1710 | PFAM: Uroporphyrinogen III synthase HEM4; KEGG: pai:PAE2594 uroporphyrinogen-III synthase (HemD), conjectural. | TIGRFAM: siroheme synthase; KEGG: pai:PAE0585 siroheme synthesis protein, conjectural. | 0.400 |
Pcal_1458 | Pcal_1712 | Pcal_1458 | Pcal_1712 | PFAM: Uroporphyrinogen III synthase HEM4; KEGG: pai:PAE2594 uroporphyrinogen-III synthase (HemD), conjectural. | PFAM: Uroporphyrinogen III synthase HEM4; KEGG: pai:PAE0589 uroporphyrinogen-III synthase. | 0.900 |
Pcal_1458 | Pcal_1713 | Pcal_1458 | Pcal_1713 | PFAM: Uroporphyrinogen III synthase HEM4; KEGG: pai:PAE2594 uroporphyrinogen-III synthase (HemD), conjectural. | TIGRFAM: uroporphyrin-III C-methyltransferase; PFAM: Uroporphyrin-III C/tetrapyrrole (Corrin/Porphyrin) methyltransferase; KEGG: pai:PAE0590 uroporphyrin-III C-methyltransferase. | 0.955 |
Pcal_1458 | hemA1 | Pcal_1458 | Pcal_1481 | PFAM: Uroporphyrinogen III synthase HEM4; KEGG: pai:PAE2594 uroporphyrinogen-III synthase (HemD), conjectural. | glutamyl-tRNA reductase; Catalyzes the NADPH-dependent reduction of glutamyl-tRNA(Glu) to glutamate 1-semialdehyde (GSA). | 0.502 |
Pcal_1458 | hemA2 | Pcal_1458 | Pcal_2034 | PFAM: Uroporphyrinogen III synthase HEM4; KEGG: pai:PAE2594 uroporphyrinogen-III synthase (HemD), conjectural. | glutamyl-tRNA reductase; Catalyzes the NADPH-dependent reduction of glutamyl-tRNA(Glu) to glutamate 1-semialdehyde (GSA). | 0.502 |
Pcal_1458 | hemC | Pcal_1458 | Pcal_1707 | PFAM: Uroporphyrinogen III synthase HEM4; KEGG: pai:PAE2594 uroporphyrinogen-III synthase (HemD), conjectural. | Porphobilinogen deaminase; Tetrapolymerization of the monopyrrole PBG into the hydroxymethylbilane pre-uroporphyrinogen in several discrete steps. | 0.990 |
Pcal_1458 | hemL | Pcal_1458 | Pcal_1717 | PFAM: Uroporphyrinogen III synthase HEM4; KEGG: pai:PAE2594 uroporphyrinogen-III synthase (HemD), conjectural. | TIGRFAM: glutamate-1-semialdehyde-2,1-aminomutase; PFAM: aminotransferase class-III; KEGG: pai:PAE0594 glutamate-1-semialdehyde aminotransferase (hemL); Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. HemL subfamily. | 0.410 |
Pcal_1708 | Pcal_1709 | Pcal_1708 | Pcal_1709 | Transcriptional regulator, AsnC family; KEGG: pai:PAE0581 heme biosynthesis protein. | Porphobilinogen synthase; PFAM: delta-aminolevulinic acid dehydratase; KEGG: pai:PAE0583 porphobilinogen synthase (delta-aminolevulinic acid dehydratase); Belongs to the ALAD family. | 0.674 |
Pcal_1708 | Pcal_1710 | Pcal_1708 | Pcal_1710 | Transcriptional regulator, AsnC family; KEGG: pai:PAE0581 heme biosynthesis protein. | TIGRFAM: siroheme synthase; KEGG: pai:PAE0585 siroheme synthesis protein, conjectural. | 0.710 |
Pcal_1708 | Pcal_1712 | Pcal_1708 | Pcal_1712 | Transcriptional regulator, AsnC family; KEGG: pai:PAE0581 heme biosynthesis protein. | PFAM: Uroporphyrinogen III synthase HEM4; KEGG: pai:PAE0589 uroporphyrinogen-III synthase. | 0.521 |