node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
Pcal_0377 | guaA | Pcal_0377 | Pcal_1723 | PFAM: aspartate/glutamate/uridylate kinase; KEGG: pai:PAE2877 aspartate kinase. | GMP synthase (glutamine-hydrolyzing); Catalyzes the synthesis of GMP from XMP. | 0.616 |
Pcal_0377 | hemL | Pcal_0377 | Pcal_1717 | PFAM: aspartate/glutamate/uridylate kinase; KEGG: pai:PAE2877 aspartate kinase. | TIGRFAM: glutamate-1-semialdehyde-2,1-aminomutase; PFAM: aminotransferase class-III; KEGG: pai:PAE0594 glutamate-1-semialdehyde aminotransferase (hemL); Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. HemL subfamily. | 0.760 |
Pcal_0839 | eno | Pcal_0839 | Pcal_0022 | PFAM: AMP-dependent synthetase and ligase; KEGG: pai:PAE1379 long-chain-fatty-acid--CoA ligase. | Enolase; Catalyzes the reversible conversion of 2-phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis; Belongs to the enolase family. | 0.473 |
Pcal_0839 | hemL | Pcal_0839 | Pcal_1717 | PFAM: AMP-dependent synthetase and ligase; KEGG: pai:PAE1379 long-chain-fatty-acid--CoA ligase. | TIGRFAM: glutamate-1-semialdehyde-2,1-aminomutase; PFAM: aminotransferase class-III; KEGG: pai:PAE0594 glutamate-1-semialdehyde aminotransferase (hemL); Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. HemL subfamily. | 0.594 |
Pcal_1486 | Pcal_1709 | Pcal_1486 | Pcal_1709 | PFAM: cytochrome c assembly protein; KEGG: pai:PAE3621 transport protein, putative. | Porphobilinogen synthase; PFAM: delta-aminolevulinic acid dehydratase; KEGG: pai:PAE0583 porphobilinogen synthase (delta-aminolevulinic acid dehydratase); Belongs to the ALAD family. | 0.611 |
Pcal_1486 | guaA | Pcal_1486 | Pcal_1723 | PFAM: cytochrome c assembly protein; KEGG: pai:PAE3621 transport protein, putative. | GMP synthase (glutamine-hydrolyzing); Catalyzes the synthesis of GMP from XMP. | 0.422 |
Pcal_1486 | hemA1 | Pcal_1486 | Pcal_1481 | PFAM: cytochrome c assembly protein; KEGG: pai:PAE3621 transport protein, putative. | glutamyl-tRNA reductase; Catalyzes the NADPH-dependent reduction of glutamyl-tRNA(Glu) to glutamate 1-semialdehyde (GSA). | 0.800 |
Pcal_1486 | hemA2 | Pcal_1486 | Pcal_2034 | PFAM: cytochrome c assembly protein; KEGG: pai:PAE3621 transport protein, putative. | glutamyl-tRNA reductase; Catalyzes the NADPH-dependent reduction of glutamyl-tRNA(Glu) to glutamate 1-semialdehyde (GSA). | 0.600 |
Pcal_1486 | hemC | Pcal_1486 | Pcal_1707 | PFAM: cytochrome c assembly protein; KEGG: pai:PAE3621 transport protein, putative. | Porphobilinogen deaminase; Tetrapolymerization of the monopyrrole PBG into the hydroxymethylbilane pre-uroporphyrinogen in several discrete steps. | 0.638 |
Pcal_1486 | hemL | Pcal_1486 | Pcal_1717 | PFAM: cytochrome c assembly protein; KEGG: pai:PAE3621 transport protein, putative. | TIGRFAM: glutamate-1-semialdehyde-2,1-aminomutase; PFAM: aminotransferase class-III; KEGG: pai:PAE0594 glutamate-1-semialdehyde aminotransferase (hemL); Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. HemL subfamily. | 0.666 |
Pcal_1709 | Pcal_1486 | Pcal_1709 | Pcal_1486 | Porphobilinogen synthase; PFAM: delta-aminolevulinic acid dehydratase; KEGG: pai:PAE0583 porphobilinogen synthase (delta-aminolevulinic acid dehydratase); Belongs to the ALAD family. | PFAM: cytochrome c assembly protein; KEGG: pai:PAE3621 transport protein, putative. | 0.611 |
Pcal_1709 | guaA | Pcal_1709 | Pcal_1723 | Porphobilinogen synthase; PFAM: delta-aminolevulinic acid dehydratase; KEGG: pai:PAE0583 porphobilinogen synthase (delta-aminolevulinic acid dehydratase); Belongs to the ALAD family. | GMP synthase (glutamine-hydrolyzing); Catalyzes the synthesis of GMP from XMP. | 0.536 |
Pcal_1709 | hemA1 | Pcal_1709 | Pcal_1481 | Porphobilinogen synthase; PFAM: delta-aminolevulinic acid dehydratase; KEGG: pai:PAE0583 porphobilinogen synthase (delta-aminolevulinic acid dehydratase); Belongs to the ALAD family. | glutamyl-tRNA reductase; Catalyzes the NADPH-dependent reduction of glutamyl-tRNA(Glu) to glutamate 1-semialdehyde (GSA). | 0.747 |
Pcal_1709 | hemA2 | Pcal_1709 | Pcal_2034 | Porphobilinogen synthase; PFAM: delta-aminolevulinic acid dehydratase; KEGG: pai:PAE0583 porphobilinogen synthase (delta-aminolevulinic acid dehydratase); Belongs to the ALAD family. | glutamyl-tRNA reductase; Catalyzes the NADPH-dependent reduction of glutamyl-tRNA(Glu) to glutamate 1-semialdehyde (GSA). | 0.735 |
Pcal_1709 | hemC | Pcal_1709 | Pcal_1707 | Porphobilinogen synthase; PFAM: delta-aminolevulinic acid dehydratase; KEGG: pai:PAE0583 porphobilinogen synthase (delta-aminolevulinic acid dehydratase); Belongs to the ALAD family. | Porphobilinogen deaminase; Tetrapolymerization of the monopyrrole PBG into the hydroxymethylbilane pre-uroporphyrinogen in several discrete steps. | 0.998 |
Pcal_1709 | hemL | Pcal_1709 | Pcal_1717 | Porphobilinogen synthase; PFAM: delta-aminolevulinic acid dehydratase; KEGG: pai:PAE0583 porphobilinogen synthase (delta-aminolevulinic acid dehydratase); Belongs to the ALAD family. | TIGRFAM: glutamate-1-semialdehyde-2,1-aminomutase; PFAM: aminotransferase class-III; KEGG: pai:PAE0594 glutamate-1-semialdehyde aminotransferase (hemL); Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. HemL subfamily. | 0.993 |
Pcal_1716 | hemL | Pcal_1716 | Pcal_1717 | PFAM: Radical SAM domain protein; SMART: Elongator protein 3/MiaB/NifB; KEGG: pai:PAE0596 metallo cofactor biosynthesis protein. | TIGRFAM: glutamate-1-semialdehyde-2,1-aminomutase; PFAM: aminotransferase class-III; KEGG: pai:PAE0594 glutamate-1-semialdehyde aminotransferase (hemL); Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. HemL subfamily. | 0.781 |
eno | Pcal_0839 | Pcal_0022 | Pcal_0839 | Enolase; Catalyzes the reversible conversion of 2-phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis; Belongs to the enolase family. | PFAM: AMP-dependent synthetase and ligase; KEGG: pai:PAE1379 long-chain-fatty-acid--CoA ligase. | 0.473 |
eno | guaA | Pcal_0022 | Pcal_1723 | Enolase; Catalyzes the reversible conversion of 2-phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis; Belongs to the enolase family. | GMP synthase (glutamine-hydrolyzing); Catalyzes the synthesis of GMP from XMP. | 0.698 |
eno | hemC | Pcal_0022 | Pcal_1707 | Enolase; Catalyzes the reversible conversion of 2-phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis; Belongs to the enolase family. | Porphobilinogen deaminase; Tetrapolymerization of the monopyrrole PBG into the hydroxymethylbilane pre-uroporphyrinogen in several discrete steps. | 0.488 |