node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
GFO_0499 | ilvD | GFO_0499 | GFO_2113 | Branched-chain-amino-acid aminotransferase; Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family. | Dihydroxy-acid dehydratase; Belongs to the IlvD/Edd family. | 0.974 |
GFO_0499 | ilvE | GFO_0499 | GFO_1441 | Branched-chain-amino-acid aminotransferase; Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family. | Branched-chain-amino-acid aminotransferase. | 0.900 |
GFO_0499 | panB | GFO_0499 | GFO_2090 | Branched-chain-amino-acid aminotransferase; Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family. | 3-methyl-2-oxobutanoatehydroxymethyltransferase; Catalyzes the reversible reaction in which hydroxymethyl group from 5,10-methylenetetrahydrofolate is transferred onto alpha- ketoisovalerate to form ketopantoate; Belongs to the PanB family. | 0.913 |
GFO_2089 | panB | GFO_2089 | GFO_2090 | Conserved hypothetical protein. | 3-methyl-2-oxobutanoatehydroxymethyltransferase; Catalyzes the reversible reaction in which hydroxymethyl group from 5,10-methylenetetrahydrofolate is transferred onto alpha- ketoisovalerate to form ketopantoate; Belongs to the PanB family. | 0.613 |
GFO_2089 | rluD-2 | GFO_2089 | GFO_2091 | Conserved hypothetical protein. | Pseudouridylate synthase. | 0.410 |
ilvD | GFO_0499 | GFO_2113 | GFO_0499 | Dihydroxy-acid dehydratase; Belongs to the IlvD/Edd family. | Branched-chain-amino-acid aminotransferase; Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family. | 0.974 |
ilvD | ilvE | GFO_2113 | GFO_1441 | Dihydroxy-acid dehydratase; Belongs to the IlvD/Edd family. | Branched-chain-amino-acid aminotransferase. | 0.974 |
ilvD | panB | GFO_2113 | GFO_2090 | Dihydroxy-acid dehydratase; Belongs to the IlvD/Edd family. | 3-methyl-2-oxobutanoatehydroxymethyltransferase; Catalyzes the reversible reaction in which hydroxymethyl group from 5,10-methylenetetrahydrofolate is transferred onto alpha- ketoisovalerate to form ketopantoate; Belongs to the PanB family. | 0.922 |
ilvE | GFO_0499 | GFO_1441 | GFO_0499 | Branched-chain-amino-acid aminotransferase. | Branched-chain-amino-acid aminotransferase; Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family. | 0.900 |
ilvE | ilvD | GFO_1441 | GFO_2113 | Branched-chain-amino-acid aminotransferase. | Dihydroxy-acid dehydratase; Belongs to the IlvD/Edd family. | 0.974 |
ilvE | panB | GFO_1441 | GFO_2090 | Branched-chain-amino-acid aminotransferase. | 3-methyl-2-oxobutanoatehydroxymethyltransferase; Catalyzes the reversible reaction in which hydroxymethyl group from 5,10-methylenetetrahydrofolate is transferred onto alpha- ketoisovalerate to form ketopantoate; Belongs to the PanB family. | 0.913 |
nadC | panB | GFO_1102 | GFO_2090 | Nicotinate-nucleotide pyrophosphorylase; Belongs to the NadC/ModD family. | 3-methyl-2-oxobutanoatehydroxymethyltransferase; Catalyzes the reversible reaction in which hydroxymethyl group from 5,10-methylenetetrahydrofolate is transferred onto alpha- ketoisovalerate to form ketopantoate; Belongs to the PanB family. | 0.666 |
nadC | panC | GFO_1102 | GFO_3544 | Nicotinate-nucleotide pyrophosphorylase; Belongs to the NadC/ModD family. | Pantoate-beta-alanine ligase; Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate. Belongs to the pantothenate synthetase family. | 0.491 |
panB | GFO_0499 | GFO_2090 | GFO_0499 | 3-methyl-2-oxobutanoatehydroxymethyltransferase; Catalyzes the reversible reaction in which hydroxymethyl group from 5,10-methylenetetrahydrofolate is transferred onto alpha- ketoisovalerate to form ketopantoate; Belongs to the PanB family. | Branched-chain-amino-acid aminotransferase; Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family. | 0.913 |
panB | GFO_2089 | GFO_2090 | GFO_2089 | 3-methyl-2-oxobutanoatehydroxymethyltransferase; Catalyzes the reversible reaction in which hydroxymethyl group from 5,10-methylenetetrahydrofolate is transferred onto alpha- ketoisovalerate to form ketopantoate; Belongs to the PanB family. | Conserved hypothetical protein. | 0.613 |
panB | ilvD | GFO_2090 | GFO_2113 | 3-methyl-2-oxobutanoatehydroxymethyltransferase; Catalyzes the reversible reaction in which hydroxymethyl group from 5,10-methylenetetrahydrofolate is transferred onto alpha- ketoisovalerate to form ketopantoate; Belongs to the PanB family. | Dihydroxy-acid dehydratase; Belongs to the IlvD/Edd family. | 0.922 |
panB | ilvE | GFO_2090 | GFO_1441 | 3-methyl-2-oxobutanoatehydroxymethyltransferase; Catalyzes the reversible reaction in which hydroxymethyl group from 5,10-methylenetetrahydrofolate is transferred onto alpha- ketoisovalerate to form ketopantoate; Belongs to the PanB family. | Branched-chain-amino-acid aminotransferase. | 0.913 |
panB | nadC | GFO_2090 | GFO_1102 | 3-methyl-2-oxobutanoatehydroxymethyltransferase; Catalyzes the reversible reaction in which hydroxymethyl group from 5,10-methylenetetrahydrofolate is transferred onto alpha- ketoisovalerate to form ketopantoate; Belongs to the PanB family. | Nicotinate-nucleotide pyrophosphorylase; Belongs to the NadC/ModD family. | 0.666 |
panB | panC | GFO_2090 | GFO_3544 | 3-methyl-2-oxobutanoatehydroxymethyltransferase; Catalyzes the reversible reaction in which hydroxymethyl group from 5,10-methylenetetrahydrofolate is transferred onto alpha- ketoisovalerate to form ketopantoate; Belongs to the PanB family. | Pantoate-beta-alanine ligase; Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate. Belongs to the pantothenate synthetase family. | 0.997 |
panB | panD | GFO_2090 | GFO_3543 | 3-methyl-2-oxobutanoatehydroxymethyltransferase; Catalyzes the reversible reaction in which hydroxymethyl group from 5,10-methylenetetrahydrofolate is transferred onto alpha- ketoisovalerate to form ketopantoate; Belongs to the PanB family. | Aspartate 1-decarboxylase; Catalyzes the pyruvoyl-dependent decarboxylation of aspartate to produce beta-alanine. | 0.941 |