STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
some 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
rplEThis is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits; this bridge is implicated in subunit movement. Contacts the P site tRNA; the 5S rRNA and some of its associated proteins might help stabilize positioning of ribosome-bound tRNAs (183 aa)    
Predicted Functional Partners:
rpsB
Small subunit ribosomal protein s2; Belongs to the universal ribosomal protein uS2 family
 
 
 0.999
rpsI
Small subunit ribosomal protein s9; Belongs to the universal ribosomal protein uS9 family
 
 
 0.999
rplM
Large subunit ribosomal protein l13; This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly
 
 0.999
rpsO
Small subunit ribosomal protein s15; One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it helps nucleate assembly of the platform of the 30S subunit by binding and bridging several RNA helices of the 16S rRNA
   
 
 0.999
rplT
Large subunit ribosomal protein l20; Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit
   
 
 0.999
rpmI
Large subunit ribosomal protein l35; Belongs to the bacterial ribosomal protein bL35 family
   
 
 0.999
rplS
Large subunit ribosomal protein l19; This protein is located at the 30S-50S ribosomal subunit interface and may play a role in the structure and function of the aminoacyl-tRNA binding site
  
 
 0.999
rpmE2
Large subunit ribosomal protein l31; Belongs to the bacterial ribosomal protein bL31 family
  
 
 0.999
rpsF
Small subunit ribosomal protein s6; Binds together with S18 to 16S ribosomal RNA
   
 
 0.999
rpsR
Small subunit ribosomal protein s18; Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit
  
 
 0.999
Your Current Organism:
Gramella forsetii
NCBI taxonomy Id: 411154
Other names: G. forsetii KT0803, Gramella forsetii KT0803, Gramella forsetii str. KT0803, Gramella forsetii strain KT0803
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