| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| EDR47751.1 | EDR47754.1 | DORFOR_00832 | DORFOR_00835 | Glycosyltransferase, group 1 family protein; KEGG: mth:MTH450 1.6e-16 LPS biosynthesis RfbU related protein K00754; COG: COG0438 Glycosyltransferase; Psort location: Cytoplasmic, score: 8.87. | Hypothetical protein; COG: NOG21970 non supervised orthologous group. | 0.434 |
| EDR47751.1 | folA | DORFOR_00832 | DORFOR_00833 | Glycosyltransferase, group 1 family protein; KEGG: mth:MTH450 1.6e-16 LPS biosynthesis RfbU related protein K00754; COG: COG0438 Glycosyltransferase; Psort location: Cytoplasmic, score: 8.87. | Dihydrofolate reductase; Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis. | 0.779 |
| EDR47751.1 | thyA | DORFOR_00832 | DORFOR_00834 | Glycosyltransferase, group 1 family protein; KEGG: mth:MTH450 1.6e-16 LPS biosynthesis RfbU related protein K00754; COG: COG0438 Glycosyltransferase; Psort location: Cytoplasmic, score: 8.87. | Thymidylate synthase; Catalyzes the reductive methylation of 2'-deoxyuridine-5'- monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by- product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis. | 0.658 |
| EDR47754.1 | EDR47751.1 | DORFOR_00835 | DORFOR_00832 | Hypothetical protein; COG: NOG21970 non supervised orthologous group. | Glycosyltransferase, group 1 family protein; KEGG: mth:MTH450 1.6e-16 LPS biosynthesis RfbU related protein K00754; COG: COG0438 Glycosyltransferase; Psort location: Cytoplasmic, score: 8.87. | 0.434 |
| EDR47754.1 | EDR47755.1 | DORFOR_00835 | DORFOR_00836 | Hypothetical protein; COG: NOG21970 non supervised orthologous group. | Flavodoxin; KEGG: syn:sll0219 3.9e-08 potential FMN-protein; COG: COG0716 Flavodoxins; Psort location: Cytoplasmic, score: 8.87. | 0.737 |
| EDR47754.1 | EDR47756.1 | DORFOR_00835 | DORFOR_00837 | Hypothetical protein; COG: NOG21970 non supervised orthologous group. | Hypothetical protein; COG: NOG11752 non supervised orthologous group; Psort location: Cytoplasmic, score: 8.87. | 0.795 |
| EDR47754.1 | folA | DORFOR_00835 | DORFOR_00833 | Hypothetical protein; COG: NOG21970 non supervised orthologous group. | Dihydrofolate reductase; Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis. | 0.439 |
| EDR47754.1 | thyA | DORFOR_00835 | DORFOR_00834 | Hypothetical protein; COG: NOG21970 non supervised orthologous group. | Thymidylate synthase; Catalyzes the reductive methylation of 2'-deoxyuridine-5'- monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by- product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis. | 0.505 |
| EDR47755.1 | EDR47754.1 | DORFOR_00836 | DORFOR_00835 | Flavodoxin; KEGG: syn:sll0219 3.9e-08 potential FMN-protein; COG: COG0716 Flavodoxins; Psort location: Cytoplasmic, score: 8.87. | Hypothetical protein; COG: NOG21970 non supervised orthologous group. | 0.737 |
| EDR47755.1 | EDR47756.1 | DORFOR_00836 | DORFOR_00837 | Flavodoxin; KEGG: syn:sll0219 3.9e-08 potential FMN-protein; COG: COG0716 Flavodoxins; Psort location: Cytoplasmic, score: 8.87. | Hypothetical protein; COG: NOG11752 non supervised orthologous group; Psort location: Cytoplasmic, score: 8.87. | 0.929 |
| EDR47755.1 | thyA | DORFOR_00836 | DORFOR_00834 | Flavodoxin; KEGG: syn:sll0219 3.9e-08 potential FMN-protein; COG: COG0716 Flavodoxins; Psort location: Cytoplasmic, score: 8.87. | Thymidylate synthase; Catalyzes the reductive methylation of 2'-deoxyuridine-5'- monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by- product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis. | 0.413 |
| EDR47756.1 | EDR47754.1 | DORFOR_00837 | DORFOR_00835 | Hypothetical protein; COG: NOG11752 non supervised orthologous group; Psort location: Cytoplasmic, score: 8.87. | Hypothetical protein; COG: NOG21970 non supervised orthologous group. | 0.795 |
| EDR47756.1 | EDR47755.1 | DORFOR_00837 | DORFOR_00836 | Hypothetical protein; COG: NOG11752 non supervised orthologous group; Psort location: Cytoplasmic, score: 8.87. | Flavodoxin; KEGG: syn:sll0219 3.9e-08 potential FMN-protein; COG: COG0716 Flavodoxins; Psort location: Cytoplasmic, score: 8.87. | 0.929 |
| folA | EDR47751.1 | DORFOR_00833 | DORFOR_00832 | Dihydrofolate reductase; Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis. | Glycosyltransferase, group 1 family protein; KEGG: mth:MTH450 1.6e-16 LPS biosynthesis RfbU related protein K00754; COG: COG0438 Glycosyltransferase; Psort location: Cytoplasmic, score: 8.87. | 0.779 |
| folA | EDR47754.1 | DORFOR_00833 | DORFOR_00835 | Dihydrofolate reductase; Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis. | Hypothetical protein; COG: NOG21970 non supervised orthologous group. | 0.439 |
| folA | thyA | DORFOR_00833 | DORFOR_00834 | Dihydrofolate reductase; Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis. | Thymidylate synthase; Catalyzes the reductive methylation of 2'-deoxyuridine-5'- monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by- product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis. | 0.998 |
| thyA | EDR47751.1 | DORFOR_00834 | DORFOR_00832 | Thymidylate synthase; Catalyzes the reductive methylation of 2'-deoxyuridine-5'- monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by- product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis. | Glycosyltransferase, group 1 family protein; KEGG: mth:MTH450 1.6e-16 LPS biosynthesis RfbU related protein K00754; COG: COG0438 Glycosyltransferase; Psort location: Cytoplasmic, score: 8.87. | 0.658 |
| thyA | EDR47754.1 | DORFOR_00834 | DORFOR_00835 | Thymidylate synthase; Catalyzes the reductive methylation of 2'-deoxyuridine-5'- monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by- product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis. | Hypothetical protein; COG: NOG21970 non supervised orthologous group. | 0.505 |
| thyA | EDR47755.1 | DORFOR_00834 | DORFOR_00836 | Thymidylate synthase; Catalyzes the reductive methylation of 2'-deoxyuridine-5'- monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by- product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis. | Flavodoxin; KEGG: syn:sll0219 3.9e-08 potential FMN-protein; COG: COG0716 Flavodoxins; Psort location: Cytoplasmic, score: 8.87. | 0.413 |
| thyA | folA | DORFOR_00834 | DORFOR_00833 | Thymidylate synthase; Catalyzes the reductive methylation of 2'-deoxyuridine-5'- monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by- product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis. | Dihydrofolate reductase; Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis. | 0.998 |