STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
EDR47754.1Hypothetical protein; COG: NOG21970 non supervised orthologous group. (109 aa)    
Predicted Functional Partners:
EDR47756.1
Hypothetical protein; COG: NOG11752 non supervised orthologous group; Psort location: Cytoplasmic, score: 8.87.
 
     0.795
EDR47755.1
Flavodoxin; KEGG: syn:sll0219 3.9e-08 potential FMN-protein; COG: COG0716 Flavodoxins; Psort location: Cytoplasmic, score: 8.87.
 
     0.737
thyA
Thymidylate synthase; Catalyzes the reductive methylation of 2'-deoxyuridine-5'- monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by- product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis.
       0.505
folA
Dihydrofolate reductase; Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis.
       0.439
EDR47751.1
Glycosyltransferase, group 1 family protein; KEGG: mth:MTH450 1.6e-16 LPS biosynthesis RfbU related protein K00754; COG: COG0438 Glycosyltransferase; Psort location: Cytoplasmic, score: 8.87.
       0.434
Your Current Organism:
Dorea formicigenerans
NCBI taxonomy Id: 411461
Other names: D. formicigenerans ATCC 27755, Dorea formicigenerans ATCC 27755
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