STRINGSTRING
prfC protein (Pseudoflavonifractor capillosus) - STRING interaction network
"prfC" - Peptide chain release factor 3 in Pseudoflavonifractor capillosus
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
some 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
prfCPeptide chain release factor 3 ; Increases the formation of ribosomal termination complexes and stimulates activities of RF-1 and RF-2. It binds guanine nucleotides and has strong preference for UGA stop codons. It may interact directly with the ribosome. The stimulation of RF- 1 and RF-2 is significantly reduced by GTP and GDP, but not by GMP (534 aa)    
Predicted Functional Partners:
BACCAP_00598
HAD hydrolase, family IA, variant 1 (213 aa)
              0.686
BACCAP_00900
Glutamate synthase [NADPH], large subunit (1551 aa)
           
  0.631
BACCAP_00596
Uncharacterized protein (74 aa)
              0.540
BACCAP_04760
tRNA-dihydrouridine synthase ; Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines (311 aa)
 
        0.531
prfA
Peptide chain release factor 1 ; Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA (355 aa)
     
 
  0.516
BACCAP_00940
Glutamine amidotransferase ; Catalyzes the synthesis of GMP from XMP (513 aa)
 
   
  0.508
pheT
Phenylalanyl-tRNA synthetase beta subunit (799 aa)
   
   
  0.478
rimI
Ribosomal-protein-alanine acetyltransferase (151 aa)
   
        0.472
polA
DNA polymerase (889 aa)
         
  0.445
BACCAP_00597
Response regulator receiver domain protein (274 aa)
              0.442
Your Current Organism:
Pseudoflavonifractor capillosus
NCBI taxonomy Id: 411467
Other names: Bacillus capillosus, Bacteroides capillosus, Bacteroides capillosus ATCC 29799, P. capillosus, P. capillosus ATCC 29799, Pseudobacterium capillosum, Pseudoflavonifractor, Pseudoflavonifractor Carlier et al. 2010, Pseudoflavonifractor capillosus, Pseudoflavonifractor capillosus ATCC 29799, Pseudoflavonifractor capillosus str. ATCC 29799, Pseudoflavonifractor capillosus strain ATCC 29799, Ristella capillosa
Server load: low (10%) [HD]