STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
serCPhosphoserine aminotransferase; Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine; Belongs to the class-V pyridoxal-phosphate-dependent aminotransferase family. SerC subfamily. (359 aa)    
Predicted Functional Partners:
serA
D-isomer specific 2-hydroxyacid dehydrogenase.
 
 0.997
pheA
Bifunctional protein PheA; Bifunctional chorismate mutase / prephenate dehydratase in phenylalanine, tyrosine and tryptophan biosynthesis pathway.
  
  
 0.976
pdxB
Erythronate-4-phosphate dehyrogenase; Catalyzes the oxidation of erythronate-4-phosphate to 3- hydroxy-2-oxo-4-phosphonooxybutanoate.
  
 0.976
serB
Phosphoserine phosphatase.
  
 
 0.943
thrC
Threonine synthase; Catalyzes the gamma-elimination of phosphate from L- phosphohomoserine and the beta-addition of water to produce L- threonine.
   
 0.927
pdxA
4-hydroxythreonine-4-phosphate dehydrogenase; Belongs to the PdxA family.
     
 0.909
trmE
tRNA modification GTPase; Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34; Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. TrmE GTPase family.
 
      0.820
aroA
3-phosphoshikimate 1-carboxyvinyltransferase; Catalyzes the transfer of the enolpyruvyl moiety of phosphoenolpyruvate (PEP) to the 5-hydroxyl of shikimate-3-phosphate (S3P) to produce enolpyruvyl shikimate-3-phosphate and inorganic phosphate.
  
  
 0.802
COSY_0577
Prephenate dehydrogenase; Similar to the N-terminal region of bifunctional protein TyrA PFL_4310 (741 aa) in Pseudomonas fluorescens Pf-5, prephenate dehydrogenase / 3-phosphoshikimate 1-carboxyvinyltransferase (EC:1.2.1.3 EC:5.4.99.5).
  
  
 0.729
dapD
2,3,4,5-tetrahydropyridine-2-carboxylate N-succinyltransferase; Belongs to the transferase hexapeptide repeat family.
   
 
 0.560
Your Current Organism:
Vesicomyosocius okutanii
NCBI taxonomy Id: 412965
Other names: C. Vesicomyosocius okutanii HA, Calyptogena okutanii thioautotrophic gill symbiont HA, Candidatus Vesicomyosocius okutanii HA, Candidatus Vesicomyosocius okutanii str. HA, Candidatus Vesicomyosocius okutanii strain HA
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