STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
proCPyrroline-5-carboxylate reductase; Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline. (268 aa)    
Predicted Functional Partners:
CBO3183
Putative pyruvate formate lyase.
    
 0.956
CBO2575
Ornithine cyclodeaminase/mu-crystallin family protein.
   
 
 0.937
prdF
Putative proline racemase; Belongs to the proline racemase family.
    
 0.919
pepIP
Proline iminopeptidase; Releases the N-terminal proline from various substrates. Belongs to the peptidase S33 family.
    
 0.902
CBO2099
Putative proline iminopeptidase.
    
 0.902
guaA
GMP synthase [glutamine-hydrolyzing]; Catalyzes the synthesis of GMP from XMP.
     
 0.759
hypD
Hydrogenase isoenzymes formation protein.
      
 0.674
adK
Adenylate kinase; Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism; Belongs to the adenylate kinase family.
   
  
 0.655
purL
Formylglycinamidine ribonucleotide synthetase.
     
 0.651
atpH
ATP synthase subunit delta; F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation.
      
 0.642
Your Current Organism:
Clostridium botulinum A ATCC 3502
NCBI taxonomy Id: 413999
Other names: C. botulinum A str. ATCC 3502, Clostridium botulinum A str. ATCC 3502, Clostridium botulinum A strain ATCC 3502
Server load: low (30%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.