STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
hemLTIGRFAM: glutamate-1-semialdehyde-2,1-aminomutase; PFAM: aminotransferase class-III; KEGG: mar:MAE_38680 glutamate-1-semialdehyde aminotransferase; Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. HemL subfamily. (433 aa)    
Predicted Functional Partners:
hemA
glutamyl-tRNA reductase; Catalyzes the NADPH-dependent reduction of glutamyl-tRNA(Glu) to glutamate 1-semialdehyde (GSA).
 
 0.992
ACK64859.1
Porphobilinogen synthase; PFAM: delta-aminolevulinic acid dehydratase; KEGG: ter:Tery_4608 delta-aminolevulinic acid dehydratase; Belongs to the ALAD family.
 
 
 0.988
ACK65612.1
Porphobilinogen synthase; PFAM: delta-aminolevulinic acid dehydratase; KEGG: mar:MAE_39770 delta-aminolevulinic acid dehydratase; Belongs to the ALAD family.
 
 
 0.988
hemC
Porphobilinogen deaminase; Tetrapolymerization of the monopyrrole PBG into the hydroxymethylbilane pre-uroporphyrinogen in several discrete steps.
 
  
 0.957
ACK67009.1
Beta-ketoacyl synthase; PFAM: phosphopantetheine-binding; Beta-ketoacyl synthase; Acyl transferase; KEGG: amr:AM1_A0228 beta-ketoacyl synthase, putative.
    
 0.905
ACK67646.1
TIGRFAM: amino acid adenylation domain protein; PFAM: AMP-dependent synthetase and ligase; condensation domain protein; phosphopantetheine-binding; type IV pilus assembly PilZ; KEGG: npu:Npun_CR072 amino acid adenylation domain-containing protein.
 
 
 0.831
ACK67643.1
TIGRFAM: amino acid adenylation domain protein; PFAM: AMP-dependent synthetase and ligase; Thioesterase; condensation domain protein; phosphopantetheine-binding; type IV pilus assembly PilZ; KEGG: npu:Npun_CR072 amino acid adenylation domain-containing protein.
 
 
 0.810
ACK67010.1
TIGRFAM: non-ribosomal peptide synthase; amino acid adenylation domain protein; PFAM: AMP-dependent synthetase and ligase; condensation domain protein; phosphopantetheine-binding; KEGG: npu:Npun_R3023 amino acid adenylation domain-containing protein; Belongs to the ATP-dependent AMP-binding enzyme family.
  
 
 0.791
hemE
Uroporphyrinogen decarboxylase; Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III.
 
  
 0.785
ACK65103.1
TIGRFAM: uroporphyrin-III C-methyltransferase; PFAM: Uroporphyrin-III C/tetrapyrrole (Corrin/Porphyrin) methyltransferase; Uroporphyrinogen III synthase HEM4; KEGG: npu:Npun_R1866 uroporphyrin-III C-methyltransferase; Belongs to the precorrin methyltransferase family.
 
  
 0.774
Your Current Organism:
Rippkaea orientalis
NCBI taxonomy Id: 41431
Other names: Cyanothece sp. PCC 8801, R. orientalis PCC 8801, Rippkaea orientalis PCC 8801, Synechococcus sp. PCC 8801, Synechococcus sp. RF-1
Server load: medium (44%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.