STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
dnaJChaperone protein DnaJ; Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins and by disaggregating proteins, also in an autonomous, DnaK-independent fashion. Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex. GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, D [...] (375 aa)    
Predicted Functional Partners:
dnaK
Chaperone protein DnaK; Acts as a chaperone; Belongs to the heat shock protein 70 family.
 0.957
dnaK-2
Chaperone protein DnaK; Acts as a chaperone; Belongs to the heat shock protein 70 family.
 
 0.951
dnaK-3
Chaperone protein DnaK; Acts as a chaperone; Belongs to the heat shock protein 70 family.
 
 0.934
grpE
GrpE protein; Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex. GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent i [...]
 
 
 0.922
ACK67643.1
TIGRFAM: amino acid adenylation domain protein; PFAM: AMP-dependent synthetase and ligase; Thioesterase; condensation domain protein; phosphopantetheine-binding; type IV pilus assembly PilZ; KEGG: npu:Npun_CR072 amino acid adenylation domain-containing protein.
   
 
 0.878
ACK67646.1
TIGRFAM: amino acid adenylation domain protein; PFAM: AMP-dependent synthetase and ligase; condensation domain protein; phosphopantetheine-binding; type IV pilus assembly PilZ; KEGG: npu:Npun_CR072 amino acid adenylation domain-containing protein.
   
 
 0.878
ACK68085.1
PFAM: Heat shock protein 70; KEGG: mar:MAE_16770 heat shock protein 70.
  
 0.865
ACK64204.1
PFAM: Respiratory-chain NADH dehydrogenase domain 51 kDa subunit; KEGG: syp:SYNPCC7002_A0196 hydrogenase large diaphorase subunit F.
    
   0.859
ACK67647.1
PFAM: AMP-dependent synthetase and ligase; KEGG: npu:Npun_R3027 amino acid adenylation domain-containing protein.
    
 
 0.826
ACK67169.1
PFAM: SirA family protein; KEGG: mar:MAE_49430 SirA-like protein; Belongs to the sulfur carrier protein TusA family.
       0.800
Your Current Organism:
Rippkaea orientalis
NCBI taxonomy Id: 41431
Other names: Cyanothece sp. PCC 8801, R. orientalis PCC 8801, Rippkaea orientalis PCC 8801, Synechococcus sp. PCC 8801, Synechococcus sp. RF-1
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.