node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
RC1_1195 | RC1_3797 | RC1_1195 | RC1_3797 | Conserved hypothetical protein; Homology to uncharacterized Phosphatidate cytidyltransferasesresides near Lipid-A biosynthesis proteins may have function related to Biosynthesis and degradation of murein sacculus and peptidoglycan; identified by match to protein family HMM PF01609. | Sugar isomerase, KpsF; Identified by match to protein family HMM PF06748. | 0.630 |
RC1_1195 | bamA | RC1_1195 | RC1_1200 | Conserved hypothetical protein; Homology to uncharacterized Phosphatidate cytidyltransferasesresides near Lipid-A biosynthesis proteins may have function related to Biosynthesis and degradation of murein sacculus and peptidoglycan; identified by match to protein family HMM PF01609. | Outer membrane protein, putative; Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane. | 0.880 |
RC1_1195 | fabZ | RC1_1195 | RC1_1197 | Conserved hypothetical protein; Homology to uncharacterized Phosphatidate cytidyltransferasesresides near Lipid-A biosynthesis proteins may have function related to Biosynthesis and degradation of murein sacculus and peptidoglycan; identified by match to protein family HMM PF01609. | Beta-hydroxyacyl-(acyl-carrier-protein) dehydratase FabZ; Involved in unsaturated fatty acids biosynthesis. Catalyzes the dehydration of short chain beta-hydroxyacyl-ACPs and long chain saturated and unsaturated beta-hydroxyacyl-ACPs. | 0.864 |
RC1_1195 | kdtA | RC1_1195 | RC1_3614 | Conserved hypothetical protein; Homology to uncharacterized Phosphatidate cytidyltransferasesresides near Lipid-A biosynthesis proteins may have function related to Biosynthesis and degradation of murein sacculus and peptidoglycan; identified by match to protein family HMM PF01609. | 3-deoxy-D-manno-octulosonic-acid transferase; Involved in lipopolysaccharide (LPS) biosynthesis. Catalyzes the transfer of 3-deoxy-D-manno-octulosonate (Kdo) residue(s) from CMP- Kdo to lipid IV(A), the tetraacyldisaccharide-1,4'-bisphosphate precursor of lipid A; Belongs to the glycosyltransferase group 1 family. | 0.750 |
RC1_1195 | lpxA | RC1_1195 | RC1_1196 | Conserved hypothetical protein; Homology to uncharacterized Phosphatidate cytidyltransferasesresides near Lipid-A biosynthesis proteins may have function related to Biosynthesis and degradation of murein sacculus and peptidoglycan; identified by match to protein family HMM PF01609. | acyl-(acyl-carrier-protein)--UDP-N- acetylglucosamine O-acyltransferase; Involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell. | 0.958 |
RC1_1195 | lpxB | RC1_1195 | RC1_1194 | Conserved hypothetical protein; Homology to uncharacterized Phosphatidate cytidyltransferasesresides near Lipid-A biosynthesis proteins may have function related to Biosynthesis and degradation of murein sacculus and peptidoglycan; identified by match to protein family HMM PF01609. | lipid-A-disaccharide synthase, putative; Condensation of UDP-2,3-diacylglucosamine and 2,3- diacylglucosamine-1-phosphate to form lipid A disaccharide, a precursor of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell. | 0.981 |
RC1_1195 | lpxC | RC1_1195 | RC1_0605 | Conserved hypothetical protein; Homology to uncharacterized Phosphatidate cytidyltransferasesresides near Lipid-A biosynthesis proteins may have function related to Biosynthesis and degradation of murein sacculus and peptidoglycan; identified by match to protein family HMM PF01609. | UDP-3-0-acyl N-acetylglucosamine deacetylase; Catalyzes the hydrolysis of UDP-3-O-myristoyl-N- acetylglucosamine to form UDP-3-O-myristoylglucosamine and acetate, the committed step in lipid A biosynthesis; Belongs to the LpxC family. | 0.734 |
RC1_1195 | lpxD | RC1_1195 | RC1_1198 | Conserved hypothetical protein; Homology to uncharacterized Phosphatidate cytidyltransferasesresides near Lipid-A biosynthesis proteins may have function related to Biosynthesis and degradation of murein sacculus and peptidoglycan; identified by match to protein family HMM PF01609. | UDP-3-O-3-hydroxymyristoyl glucosamine N-acyltransferase, putative; Catalyzes the N-acylation of UDP-3-O-acylglucosamine using 3- hydroxyacyl-ACP as the acyl donor. Is involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell. Belongs to the transferase hexapeptide repeat family. LpxD subfamily. | 0.955 |
RC1_1195 | lpxK | RC1_1195 | RC1_3613 | Conserved hypothetical protein; Homology to uncharacterized Phosphatidate cytidyltransferasesresides near Lipid-A biosynthesis proteins may have function related to Biosynthesis and degradation of murein sacculus and peptidoglycan; identified by match to protein family HMM PF01609. | Tetraacyldisaccharide 4'-kinase; Transfers the gamma-phosphate of ATP to the 4'-position of a tetraacyldisaccharide 1-phosphate intermediate (termed DS-1-P) to form tetraacyldisaccharide 1,4'-bis-phosphate (lipid IVA). | 0.812 |
RC1_3797 | RC1_1195 | RC1_3797 | RC1_1195 | Sugar isomerase, KpsF; Identified by match to protein family HMM PF06748. | Conserved hypothetical protein; Homology to uncharacterized Phosphatidate cytidyltransferasesresides near Lipid-A biosynthesis proteins may have function related to Biosynthesis and degradation of murein sacculus and peptidoglycan; identified by match to protein family HMM PF01609. | 0.630 |
RC1_3797 | bamA | RC1_3797 | RC1_1200 | Sugar isomerase, KpsF; Identified by match to protein family HMM PF06748. | Outer membrane protein, putative; Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane. | 0.540 |
RC1_3797 | kdtA | RC1_3797 | RC1_3614 | Sugar isomerase, KpsF; Identified by match to protein family HMM PF06748. | 3-deoxy-D-manno-octulosonic-acid transferase; Involved in lipopolysaccharide (LPS) biosynthesis. Catalyzes the transfer of 3-deoxy-D-manno-octulosonate (Kdo) residue(s) from CMP- Kdo to lipid IV(A), the tetraacyldisaccharide-1,4'-bisphosphate precursor of lipid A; Belongs to the glycosyltransferase group 1 family. | 0.882 |
RC1_3797 | lpxA | RC1_3797 | RC1_1196 | Sugar isomerase, KpsF; Identified by match to protein family HMM PF06748. | acyl-(acyl-carrier-protein)--UDP-N- acetylglucosamine O-acyltransferase; Involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell. | 0.889 |
RC1_3797 | lpxB | RC1_3797 | RC1_1194 | Sugar isomerase, KpsF; Identified by match to protein family HMM PF06748. | lipid-A-disaccharide synthase, putative; Condensation of UDP-2,3-diacylglucosamine and 2,3- diacylglucosamine-1-phosphate to form lipid A disaccharide, a precursor of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell. | 0.885 |
RC1_3797 | lpxC | RC1_3797 | RC1_0605 | Sugar isomerase, KpsF; Identified by match to protein family HMM PF06748. | UDP-3-0-acyl N-acetylglucosamine deacetylase; Catalyzes the hydrolysis of UDP-3-O-myristoyl-N- acetylglucosamine to form UDP-3-O-myristoylglucosamine and acetate, the committed step in lipid A biosynthesis; Belongs to the LpxC family. | 0.881 |
RC1_3797 | lpxD | RC1_3797 | RC1_1198 | Sugar isomerase, KpsF; Identified by match to protein family HMM PF06748. | UDP-3-O-3-hydroxymyristoyl glucosamine N-acyltransferase, putative; Catalyzes the N-acylation of UDP-3-O-acylglucosamine using 3- hydroxyacyl-ACP as the acyl donor. Is involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell. Belongs to the transferase hexapeptide repeat family. LpxD subfamily. | 0.879 |
RC1_3797 | lpxK | RC1_3797 | RC1_3613 | Sugar isomerase, KpsF; Identified by match to protein family HMM PF06748. | Tetraacyldisaccharide 4'-kinase; Transfers the gamma-phosphate of ATP to the 4'-position of a tetraacyldisaccharide 1-phosphate intermediate (termed DS-1-P) to form tetraacyldisaccharide 1,4'-bis-phosphate (lipid IVA). | 0.881 |
bamA | RC1_1195 | RC1_1200 | RC1_1195 | Outer membrane protein, putative; Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane. | Conserved hypothetical protein; Homology to uncharacterized Phosphatidate cytidyltransferasesresides near Lipid-A biosynthesis proteins may have function related to Biosynthesis and degradation of murein sacculus and peptidoglycan; identified by match to protein family HMM PF01609. | 0.880 |
bamA | RC1_3797 | RC1_1200 | RC1_3797 | Outer membrane protein, putative; Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane. | Sugar isomerase, KpsF; Identified by match to protein family HMM PF06748. | 0.540 |
bamA | fabZ | RC1_1200 | RC1_1197 | Outer membrane protein, putative; Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane. | Beta-hydroxyacyl-(acyl-carrier-protein) dehydratase FabZ; Involved in unsaturated fatty acids biosynthesis. Catalyzes the dehydration of short chain beta-hydroxyacyl-ACPs and long chain saturated and unsaturated beta-hydroxyacyl-ACPs. | 0.940 |