node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
RC1_1183 | kynU | RC1_1183 | RC1_2772 | Ubiquinone biosynthesis hydroxylase, UbiH; Identified by match to protein family HMM PF01026 match to protein family HMM TIGR00010. | Kynureninase; Catalyzes the cleavage of L-kynurenine (L-Kyn) and L-3- hydroxykynurenine (L-3OHKyn) into anthranilic acid (AA) and 3- hydroxyanthranilic acid (3-OHAA), respectively. | 0.436 |
acyII-2 | kynU | RC1_2771 | RC1_2772 | Penicillin acylase II, putative; Also called penicillin amidase. | Kynureninase; Catalyzes the cleavage of L-kynurenine (L-Kyn) and L-3- hydroxykynurenine (L-3OHKyn) into anthranilic acid (AA) and 3- hydroxyanthranilic acid (3-OHAA), respectively. | 0.463 |
hmgA | hppD | RC1_2510 | RC1_3343 | Homogentisate 1,2-dioxygenase. | 4-hydroxyphenylpyruvate dioxygenase. | 0.997 |
hmgA | kynU | RC1_2510 | RC1_2772 | Homogentisate 1,2-dioxygenase. | Kynureninase; Catalyzes the cleavage of L-kynurenine (L-Kyn) and L-3- hydroxykynurenine (L-3OHKyn) into anthranilic acid (AA) and 3- hydroxyanthranilic acid (3-OHAA), respectively. | 0.543 |
hppD | hmgA | RC1_3343 | RC1_2510 | 4-hydroxyphenylpyruvate dioxygenase. | Homogentisate 1,2-dioxygenase. | 0.997 |
hppD | kynA | RC1_3343 | RC1_2780 | 4-hydroxyphenylpyruvate dioxygenase. | Tryptophan 2,3-dioxygenase, putative; Heme-dependent dioxygenase that catalyzes the oxidative cleavage of the L-tryptophan (L-Trp) pyrrole ring and converts L- tryptophan to N-formyl-L-kynurenine. Catalyzes the oxidative cleavage of the indole moiety. | 0.590 |
hppD | kynU | RC1_3343 | RC1_2772 | 4-hydroxyphenylpyruvate dioxygenase. | Kynureninase; Catalyzes the cleavage of L-kynurenine (L-Kyn) and L-3- hydroxykynurenine (L-3OHKyn) into anthranilic acid (AA) and 3- hydroxyanthranilic acid (3-OHAA), respectively. | 0.510 |
hutH | kynU | RC1_3238 | RC1_2772 | Histidine ammonia-lyase; Belongs to the PAL/histidase family. | Kynureninase; Catalyzes the cleavage of L-kynurenine (L-Kyn) and L-3- hydroxykynurenine (L-3OHKyn) into anthranilic acid (AA) and 3- hydroxyanthranilic acid (3-OHAA), respectively. | 0.452 |
kat | katA | RC1_2172 | RC1_3548 | Catalase; Identified by match to protein family HMM PF00444 match to protein family HMM TIGR01022. | Catalase; Gene symbol synonym catA; identified by match to protein family HMM PF00430. | 0.909 |
kat | kynU | RC1_2172 | RC1_2772 | Catalase; Identified by match to protein family HMM PF00444 match to protein family HMM TIGR01022. | Kynureninase; Catalyzes the cleavage of L-kynurenine (L-Kyn) and L-3- hydroxykynurenine (L-3OHKyn) into anthranilic acid (AA) and 3- hydroxyanthranilic acid (3-OHAA), respectively. | 0.902 |
katA | kat | RC1_3548 | RC1_2172 | Catalase; Gene symbol synonym catA; identified by match to protein family HMM PF00430. | Catalase; Identified by match to protein family HMM PF00444 match to protein family HMM TIGR01022. | 0.909 |
katA | kynU | RC1_3548 | RC1_2772 | Catalase; Gene symbol synonym catA; identified by match to protein family HMM PF00430. | Kynureninase; Catalyzes the cleavage of L-kynurenine (L-Kyn) and L-3- hydroxykynurenine (L-3OHKyn) into anthranilic acid (AA) and 3- hydroxyanthranilic acid (3-OHAA), respectively. | 0.902 |
kynA | hppD | RC1_2780 | RC1_3343 | Tryptophan 2,3-dioxygenase, putative; Heme-dependent dioxygenase that catalyzes the oxidative cleavage of the L-tryptophan (L-Trp) pyrrole ring and converts L- tryptophan to N-formyl-L-kynurenine. Catalyzes the oxidative cleavage of the indole moiety. | 4-hydroxyphenylpyruvate dioxygenase. | 0.590 |
kynA | kynB | RC1_2780 | RC1_2776 | Tryptophan 2,3-dioxygenase, putative; Heme-dependent dioxygenase that catalyzes the oxidative cleavage of the L-tryptophan (L-Trp) pyrrole ring and converts L- tryptophan to N-formyl-L-kynurenine. Catalyzes the oxidative cleavage of the indole moiety. | Cyclase, putative; Catalyzes the hydrolysis of N-formyl-L-kynurenine to L- kynurenine, the second step in the kynurenine pathway of tryptophan degradation. | 0.994 |
kynA | kynU | RC1_2780 | RC1_2772 | Tryptophan 2,3-dioxygenase, putative; Heme-dependent dioxygenase that catalyzes the oxidative cleavage of the L-tryptophan (L-Trp) pyrrole ring and converts L- tryptophan to N-formyl-L-kynurenine. Catalyzes the oxidative cleavage of the indole moiety. | Kynureninase; Catalyzes the cleavage of L-kynurenine (L-Kyn) and L-3- hydroxykynurenine (L-3OHKyn) into anthranilic acid (AA) and 3- hydroxyanthranilic acid (3-OHAA), respectively. | 0.997 |
kynA | ubiH | RC1_2780 | RC1_2782 | Tryptophan 2,3-dioxygenase, putative; Heme-dependent dioxygenase that catalyzes the oxidative cleavage of the L-tryptophan (L-Trp) pyrrole ring and converts L- tryptophan to N-formyl-L-kynurenine. Catalyzes the oxidative cleavage of the indole moiety. | 2-polyprenyl-6-methoxyphenol 4-hydroxylase, putative. | 0.520 |
kynB | kynA | RC1_2776 | RC1_2780 | Cyclase, putative; Catalyzes the hydrolysis of N-formyl-L-kynurenine to L- kynurenine, the second step in the kynurenine pathway of tryptophan degradation. | Tryptophan 2,3-dioxygenase, putative; Heme-dependent dioxygenase that catalyzes the oxidative cleavage of the L-tryptophan (L-Trp) pyrrole ring and converts L- tryptophan to N-formyl-L-kynurenine. Catalyzes the oxidative cleavage of the indole moiety. | 0.994 |
kynB | kynU | RC1_2776 | RC1_2772 | Cyclase, putative; Catalyzes the hydrolysis of N-formyl-L-kynurenine to L- kynurenine, the second step in the kynurenine pathway of tryptophan degradation. | Kynureninase; Catalyzes the cleavage of L-kynurenine (L-Kyn) and L-3- hydroxykynurenine (L-3OHKyn) into anthranilic acid (AA) and 3- hydroxyanthranilic acid (3-OHAA), respectively. | 0.993 |
kynU | RC1_1183 | RC1_2772 | RC1_1183 | Kynureninase; Catalyzes the cleavage of L-kynurenine (L-Kyn) and L-3- hydroxykynurenine (L-3OHKyn) into anthranilic acid (AA) and 3- hydroxyanthranilic acid (3-OHAA), respectively. | Ubiquinone biosynthesis hydroxylase, UbiH; Identified by match to protein family HMM PF01026 match to protein family HMM TIGR00010. | 0.436 |
kynU | acyII-2 | RC1_2772 | RC1_2771 | Kynureninase; Catalyzes the cleavage of L-kynurenine (L-Kyn) and L-3- hydroxykynurenine (L-3OHKyn) into anthranilic acid (AA) and 3- hydroxyanthranilic acid (3-OHAA), respectively. | Penicillin acylase II, putative; Also called penicillin amidase. | 0.463 |