node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
RC1_0582 | clpA | RC1_0582 | RC1_1691 | DnaJ family, molecular chaperone, putative; PF01556 PF00226: DnaJ domain; Has many homologs from the same family; identified by match to protein family HMM PF00929. | ATP-dependent Clp protease ATP-binding subunit ClpA; PF07724 PF02861: Clp amino terminal domain; PF07728: ATPase family associated With various cellular activities (AAA); SP:P05444: ClpA homolog protein; identified by match to protein family HMM PF01343; Belongs to the ClpA/ClpB family. | 0.792 |
RC1_0582 | clpB | RC1_0582 | RC1_2633 | DnaJ family, molecular chaperone, putative; PF01556 PF00226: DnaJ domain; Has many homologs from the same family; identified by match to protein family HMM PF00929. | ATP-dependent chaperone protein ClpB; Part of a stress-induced multi-chaperone system, it is involved in the recovery of the cell from heat-induced damage, in cooperation with DnaK, DnaJ and GrpE; Belongs to the ClpA/ClpB family. | 0.792 |
RC1_0582 | dnaK-2 | RC1_0582 | RC1_2858 | DnaJ family, molecular chaperone, putative; PF01556 PF00226: DnaJ domain; Has many homologs from the same family; identified by match to protein family HMM PF00929. | Chaperone protein DnaK, putative; Acts as a chaperone; Belongs to the heat shock protein 70 family. | 0.993 |
RC1_0582 | groL | RC1_0582 | RC1_2595 | DnaJ family, molecular chaperone, putative; PF01556 PF00226: DnaJ domain; Has many homologs from the same family; identified by match to protein family HMM PF00929. | Chaperonin GroL, putative; Prevents misfolding and promotes the refolding and proper assembly of unfolded polypeptides generated under stress conditions. | 0.872 |
RC1_0582 | grpE | RC1_0582 | RC1_2956 | DnaJ family, molecular chaperone, putative; PF01556 PF00226: DnaJ domain; Has many homologs from the same family; identified by match to protein family HMM PF00929. | Co-chaperone GrpE, putative; Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex. GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of [...] | 0.951 |
RC1_0582 | hrcA | RC1_0582 | RC1_2957 | DnaJ family, molecular chaperone, putative; PF01556 PF00226: DnaJ domain; Has many homologs from the same family; identified by match to protein family HMM PF00929. | Heat-inducible transcription repressor HrcA; Negative regulator of class I heat shock genes (grpE-dnaK- dnaJ and groELS operons). Prevents heat-shock induction of these operons. | 0.796 |
RC1_0582 | htpG | RC1_0582 | RC1_2425 | DnaJ family, molecular chaperone, putative; PF01556 PF00226: DnaJ domain; Has many homologs from the same family; identified by match to protein family HMM PF00929. | Molecular chaperone,hSP90 family, putative; Molecular chaperone. Has ATPase activity. | 0.977 |
clpA | RC1_0582 | RC1_1691 | RC1_0582 | ATP-dependent Clp protease ATP-binding subunit ClpA; PF07724 PF02861: Clp amino terminal domain; PF07728: ATPase family associated With various cellular activities (AAA); SP:P05444: ClpA homolog protein; identified by match to protein family HMM PF01343; Belongs to the ClpA/ClpB family. | DnaJ family, molecular chaperone, putative; PF01556 PF00226: DnaJ domain; Has many homologs from the same family; identified by match to protein family HMM PF00929. | 0.792 |
clpA | dnaJ | RC1_1691 | RC1_2859 | ATP-dependent Clp protease ATP-binding subunit ClpA; PF07724 PF02861: Clp amino terminal domain; PF07728: ATPase family associated With various cellular activities (AAA); SP:P05444: ClpA homolog protein; identified by match to protein family HMM PF01343; Belongs to the ClpA/ClpB family. | Chaperone protein DnaJ, putative; Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins and by disaggregating proteins, also in an autonomous, DnaK-independent fashion. Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex. GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions betwe [...] | 0.832 |
clpA | dnaJ-2 | RC1_1691 | RC1_3078 | ATP-dependent Clp protease ATP-binding subunit ClpA; PF07724 PF02861: Clp amino terminal domain; PF07728: ATPase family associated With various cellular activities (AAA); SP:P05444: ClpA homolog protein; identified by match to protein family HMM PF01343; Belongs to the ClpA/ClpB family. | Chaperone protein DnaJ, putative; PF00226 Has uncharacterized homologs of the same identity; In a close position to other chaperonin genes in the same cluster. | 0.776 |
clpA | dnaJ-3 | RC1_1691 | RC1_3564 | ATP-dependent Clp protease ATP-binding subunit ClpA; PF07724 PF02861: Clp amino terminal domain; PF07728: ATPase family associated With various cellular activities (AAA); SP:P05444: ClpA homolog protein; identified by match to protein family HMM PF01343; Belongs to the ClpA/ClpB family. | Chaperone protein DnaJ, putative; PF01556 Has uncharacterized homologs of the same identity; In a close position to other chaperonin genes in the same cluster; identified by match to protein family HMM PF00106. | 0.792 |
clpA | dnaK-2 | RC1_1691 | RC1_2858 | ATP-dependent Clp protease ATP-binding subunit ClpA; PF07724 PF02861: Clp amino terminal domain; PF07728: ATPase family associated With various cellular activities (AAA); SP:P05444: ClpA homolog protein; identified by match to protein family HMM PF01343; Belongs to the ClpA/ClpB family. | Chaperone protein DnaK, putative; Acts as a chaperone; Belongs to the heat shock protein 70 family. | 0.979 |
clpA | groL | RC1_1691 | RC1_2595 | ATP-dependent Clp protease ATP-binding subunit ClpA; PF07724 PF02861: Clp amino terminal domain; PF07728: ATPase family associated With various cellular activities (AAA); SP:P05444: ClpA homolog protein; identified by match to protein family HMM PF01343; Belongs to the ClpA/ClpB family. | Chaperonin GroL, putative; Prevents misfolding and promotes the refolding and proper assembly of unfolded polypeptides generated under stress conditions. | 0.798 |
clpA | grpE | RC1_1691 | RC1_2956 | ATP-dependent Clp protease ATP-binding subunit ClpA; PF07724 PF02861: Clp amino terminal domain; PF07728: ATPase family associated With various cellular activities (AAA); SP:P05444: ClpA homolog protein; identified by match to protein family HMM PF01343; Belongs to the ClpA/ClpB family. | Co-chaperone GrpE, putative; Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex. GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of [...] | 0.880 |
clpA | hrcA | RC1_1691 | RC1_2957 | ATP-dependent Clp protease ATP-binding subunit ClpA; PF07724 PF02861: Clp amino terminal domain; PF07728: ATPase family associated With various cellular activities (AAA); SP:P05444: ClpA homolog protein; identified by match to protein family HMM PF01343; Belongs to the ClpA/ClpB family. | Heat-inducible transcription repressor HrcA; Negative regulator of class I heat shock genes (grpE-dnaK- dnaJ and groELS operons). Prevents heat-shock induction of these operons. | 0.769 |
clpA | htpG | RC1_1691 | RC1_2425 | ATP-dependent Clp protease ATP-binding subunit ClpA; PF07724 PF02861: Clp amino terminal domain; PF07728: ATPase family associated With various cellular activities (AAA); SP:P05444: ClpA homolog protein; identified by match to protein family HMM PF01343; Belongs to the ClpA/ClpB family. | Molecular chaperone,hSP90 family, putative; Molecular chaperone. Has ATPase activity. | 0.879 |
clpB | RC1_0582 | RC1_2633 | RC1_0582 | ATP-dependent chaperone protein ClpB; Part of a stress-induced multi-chaperone system, it is involved in the recovery of the cell from heat-induced damage, in cooperation with DnaK, DnaJ and GrpE; Belongs to the ClpA/ClpB family. | DnaJ family, molecular chaperone, putative; PF01556 PF00226: DnaJ domain; Has many homologs from the same family; identified by match to protein family HMM PF00929. | 0.792 |
clpB | dnaJ | RC1_2633 | RC1_2859 | ATP-dependent chaperone protein ClpB; Part of a stress-induced multi-chaperone system, it is involved in the recovery of the cell from heat-induced damage, in cooperation with DnaK, DnaJ and GrpE; Belongs to the ClpA/ClpB family. | Chaperone protein DnaJ, putative; Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins and by disaggregating proteins, also in an autonomous, DnaK-independent fashion. Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex. GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions betwe [...] | 0.832 |
clpB | dnaJ-2 | RC1_2633 | RC1_3078 | ATP-dependent chaperone protein ClpB; Part of a stress-induced multi-chaperone system, it is involved in the recovery of the cell from heat-induced damage, in cooperation with DnaK, DnaJ and GrpE; Belongs to the ClpA/ClpB family. | Chaperone protein DnaJ, putative; PF00226 Has uncharacterized homologs of the same identity; In a close position to other chaperonin genes in the same cluster. | 0.776 |
clpB | dnaJ-3 | RC1_2633 | RC1_3564 | ATP-dependent chaperone protein ClpB; Part of a stress-induced multi-chaperone system, it is involved in the recovery of the cell from heat-induced damage, in cooperation with DnaK, DnaJ and GrpE; Belongs to the ClpA/ClpB family. | Chaperone protein DnaJ, putative; PF01556 Has uncharacterized homologs of the same identity; In a close position to other chaperonin genes in the same cluster; identified by match to protein family HMM PF00106. | 0.792 |