STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
taw3-2Conserved archaeal protein; S-adenosyl-L-methionine-dependent methyltransferase that acts as a component of the wyosine derivatives biosynthesis pathway. Probably methylates N-4 position of wybutosine-86 to produce wybutosine-72; Belongs to the TYW3 family. (211 aa)    
Predicted Functional Partners:
Hbut_1145
Conserved archaeal protein; The protein has a CBS domain.
       0.574
Hbut_1143
Putative PhoH protein.
       0.552
Hbut_0440
Hypothetical protein.
   
    0.540
taw1
Conserved archaeal protein; Component of the wyosine derivatives biosynthesis pathway that catalyzes the condensation of N-methylguanine with 2 carbon atoms from pyruvate to form the tricyclic 4-demethylwyosine (imG-14) on guanosine-37 of tRNA(Phe).
  
  
 0.473
Hbut_0402
RuvB-like 2.
  
     0.418
Hbut_1636
Conserved archaeal protein.
  
     0.411
Hbut_0644
Conserved uncharacterized archaeal protein.
  
     0.405
Hbut_1141
Hypothetical protein.
       0.403
Hbut_1142
Conserved crenarchaeal protein.
       0.403
Your Current Organism:
Hyperthermus butylicus
NCBI taxonomy Id: 415426
Other names: H. butylicus DSM 5456, Hyperthermus butylicus DSM 5456, Hyperthermus butylicus str. DSM 5456, Hyperthermus butylicus strain DSM 5456
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.