node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
Hbut_0300 | Hbut_0579 | Hbut_0300 | Hbut_0579 | ATPases of AAA+ class, SpoVK, putative cell division. | 50S ribosomal protein L40e; Belongs to the eukaryotic ribosomal protein eL40 family. | 0.715 |
Hbut_0300 | pan | Hbut_0300 | Hbut_1140 | ATPases of AAA+ class, SpoVK, putative cell division. | Proteasome-activating nucleotidase; ATPase which is responsible for recognizing, binding, unfolding and translocation of substrate proteins into the archaeal 20S proteasome core particle. Is essential for opening the gate of the 20S proteasome via an interaction with its C-terminus, thereby allowing substrate entry and access to the site of proteolysis. Thus, the C- termini of the proteasomal ATPase function like a 'key in a lock' to induce gate opening and therefore regulate proteolysis. Unfolding activity requires energy from ATP hydrolysis, whereas ATP binding alone promotes ATPase- [...] | 0.628 |
Hbut_0300 | psmA | Hbut_0300 | Hbut_0568 | ATPases of AAA+ class, SpoVK, putative cell division. | Proteasome alpha subunit; Component of the proteasome core, a large protease complex with broad specificity involved in protein degradation. | 0.601 |
Hbut_0300 | psmB1 | Hbut_0300 | Hbut_1564 | ATPases of AAA+ class, SpoVK, putative cell division. | Proteasome beta subunit; Component of the proteasome core, a large protease complex with broad specificity involved in protein degradation. | 0.586 |
Hbut_0300 | psmB2 | Hbut_0300 | Hbut_1567 | ATPases of AAA+ class, SpoVK, putative cell division. | Proteasome beta precursor; Component of the proteasome core, a large protease complex with broad specificity involved in protein degradation. | 0.586 |
Hbut_0579 | Hbut_0300 | Hbut_0579 | Hbut_0300 | 50S ribosomal protein L40e; Belongs to the eukaryotic ribosomal protein eL40 family. | ATPases of AAA+ class, SpoVK, putative cell division. | 0.715 |
Hbut_0579 | Hbut_0799 | Hbut_0579 | Hbut_0799 | 50S ribosomal protein L40e; Belongs to the eukaryotic ribosomal protein eL40 family. | Predicted ATPase. | 0.715 |
Hbut_0579 | Hbut_1358 | Hbut_0579 | Hbut_1358 | 50S ribosomal protein L40e; Belongs to the eukaryotic ribosomal protein eL40 family. | ATP-dependent protease. | 0.715 |
Hbut_0579 | pan | Hbut_0579 | Hbut_1140 | 50S ribosomal protein L40e; Belongs to the eukaryotic ribosomal protein eL40 family. | Proteasome-activating nucleotidase; ATPase which is responsible for recognizing, binding, unfolding and translocation of substrate proteins into the archaeal 20S proteasome core particle. Is essential for opening the gate of the 20S proteasome via an interaction with its C-terminus, thereby allowing substrate entry and access to the site of proteolysis. Thus, the C- termini of the proteasomal ATPase function like a 'key in a lock' to induce gate opening and therefore regulate proteolysis. Unfolding activity requires energy from ATP hydrolysis, whereas ATP binding alone promotes ATPase- [...] | 0.870 |
Hbut_0579 | psmA | Hbut_0579 | Hbut_0568 | 50S ribosomal protein L40e; Belongs to the eukaryotic ribosomal protein eL40 family. | Proteasome alpha subunit; Component of the proteasome core, a large protease complex with broad specificity involved in protein degradation. | 0.755 |
Hbut_0579 | psmB1 | Hbut_0579 | Hbut_1564 | 50S ribosomal protein L40e; Belongs to the eukaryotic ribosomal protein eL40 family. | Proteasome beta subunit; Component of the proteasome core, a large protease complex with broad specificity involved in protein degradation. | 0.755 |
Hbut_0579 | psmB2 | Hbut_0579 | Hbut_1567 | 50S ribosomal protein L40e; Belongs to the eukaryotic ribosomal protein eL40 family. | Proteasome beta precursor; Component of the proteasome core, a large protease complex with broad specificity involved in protein degradation. | 0.755 |
Hbut_0799 | Hbut_0579 | Hbut_0799 | Hbut_0579 | Predicted ATPase. | 50S ribosomal protein L40e; Belongs to the eukaryotic ribosomal protein eL40 family. | 0.715 |
Hbut_0799 | pan | Hbut_0799 | Hbut_1140 | Predicted ATPase. | Proteasome-activating nucleotidase; ATPase which is responsible for recognizing, binding, unfolding and translocation of substrate proteins into the archaeal 20S proteasome core particle. Is essential for opening the gate of the 20S proteasome via an interaction with its C-terminus, thereby allowing substrate entry and access to the site of proteolysis. Thus, the C- termini of the proteasomal ATPase function like a 'key in a lock' to induce gate opening and therefore regulate proteolysis. Unfolding activity requires energy from ATP hydrolysis, whereas ATP binding alone promotes ATPase- [...] | 0.651 |
Hbut_0799 | psmA | Hbut_0799 | Hbut_0568 | Predicted ATPase. | Proteasome alpha subunit; Component of the proteasome core, a large protease complex with broad specificity involved in protein degradation. | 0.584 |
Hbut_0799 | psmB1 | Hbut_0799 | Hbut_1564 | Predicted ATPase. | Proteasome beta subunit; Component of the proteasome core, a large protease complex with broad specificity involved in protein degradation. | 0.645 |
Hbut_0799 | psmB2 | Hbut_0799 | Hbut_1567 | Predicted ATPase. | Proteasome beta precursor; Component of the proteasome core, a large protease complex with broad specificity involved in protein degradation. | 0.636 |
Hbut_1358 | Hbut_0579 | Hbut_1358 | Hbut_0579 | ATP-dependent protease. | 50S ribosomal protein L40e; Belongs to the eukaryotic ribosomal protein eL40 family. | 0.715 |
Hbut_1358 | pan | Hbut_1358 | Hbut_1140 | ATP-dependent protease. | Proteasome-activating nucleotidase; ATPase which is responsible for recognizing, binding, unfolding and translocation of substrate proteins into the archaeal 20S proteasome core particle. Is essential for opening the gate of the 20S proteasome via an interaction with its C-terminus, thereby allowing substrate entry and access to the site of proteolysis. Thus, the C- termini of the proteasomal ATPase function like a 'key in a lock' to induce gate opening and therefore regulate proteolysis. Unfolding activity requires energy from ATP hydrolysis, whereas ATP binding alone promotes ATPase- [...] | 0.627 |
Hbut_1358 | psmA | Hbut_1358 | Hbut_0568 | ATP-dependent protease. | Proteasome alpha subunit; Component of the proteasome core, a large protease complex with broad specificity involved in protein degradation. | 0.601 |