STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
eif6Translation initiation factor 6 (eIF-6); Binds to the 50S ribosomal subunit and prevents its association with the 30S ribosomal subunit to form the 70S initiation complex. (225 aa)    
Predicted Functional Partners:
rpl13e
50S ribosomal protein L13e; Belongs to the eukaryotic ribosomal protein eL13 family.
   
 
 0.999
rpl24e
50S ribosomal protein L24e; Binds to the 23S rRNA.
  
 
 0.999
rpl15e
50S ribosomal protein L15e; Belongs to the eukaryotic ribosomal protein eL15 family.
 
   0.999
rpl35ae
50S ribosomal protein L35Ae; Belongs to the eukaryotic ribosomal protein eL33 family.
   
 
 0.999
Hbut_1302
50S ribosomal protein L3P; One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit.
 
 
 0.999
rpl23
50S ribosomal protein L23P; Binds to 23S rRNA. One of the proteins that surrounds the polypeptide exit tunnel on the outside of the ribosome. Belongs to the universal ribosomal protein uL23 family.
  
 
 0.999
rpl29
50S ribosomal protein L29; Belongs to the universal ribosomal protein uL29 family.
   
 
 0.999
rpl14
50S ribosomal protein L14; Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome; Belongs to the universal ribosomal protein uL14 family.
  
 
 0.999
rpl6
50S ribosomal protein L6P; This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7/L12 stalk, and near the tRNA binding site of the peptidyltransferase center; Belongs to the universal ribosomal protein uL6 family.
  
 
 0.999
rpl19e
50S ribosomal protein L19E; Binds to the 23S rRNA; Belongs to the eukaryotic ribosomal protein eL19 family.
 
 
 0.999
Your Current Organism:
Hyperthermus butylicus
NCBI taxonomy Id: 415426
Other names: H. butylicus DSM 5456, Hyperthermus butylicus DSM 5456, Hyperthermus butylicus str. DSM 5456, Hyperthermus butylicus strain DSM 5456
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.