STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
ureBUrease subunit beta UreB; Belongs to the urease beta subunit family. (101 aa)    
Predicted Functional Partners:
ureC
Urease alpha subunit UreC; Belongs to the metallo-dependent hydrolases superfamily. Urease alpha subunit family.
 0.999
ureA
Urease gamma subunit UreA; Belongs to the urease gamma subunit family.
 0.999
ureF
Urease accessory protein UreF; Required for maturation of urease via the functional incorporation of the urease nickel metallocenter.
 
 
 0.987
ureE
Urease accessory protein UreE; Involved in urease metallocenter assembly. Binds nickel. Probably functions as a nickel donor during metallocenter assembly. Belongs to the UreE family.
 
  
 0.985
ureD
Urease accessory protein UreD; Required for maturation of urease via the functional incorporation of the urease nickel metallocenter.
 
 
 0.980
ureG
Urease accessory protein UreG; Facilitates the functional incorporation of the urease nickel metallocenter. This process requires GTP hydrolysis, probably effectuated by UreG.
 
  
 0.979
sdaA
L-serine dehydratase; Belongs to the iron-sulfur dependent L-serine dehydratase family.
      
 0.579
utp
Urea transport protein ApUT.
 
  
 0.571
hypB
Hydrogenase isoenzymes nickel incorporation protein HypB.
  
  
 0.507
gst-2
Putative glutathione S-transferase.
       0.497
Your Current Organism:
Actinobacillus pleuropneumoniae
NCBI taxonomy Id: 416269
Other names: A. pleuropneumoniae serovar 5b str. L20, Actinobacillus pleuropneumoniae L20, Actinobacillus pleuropneumoniae serovar 5b str. L20, Actinobacillus pleuropneumoniae serovar 5b strain L20
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.