node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
Tlet_0638 | Tlet_1434 | Tlet_0638 | Tlet_1434 | PFAM: cell cycle protein; KEGG: tma:TM0233 cell division protein, RodA/FtsW/spoVE family; Belongs to the SEDS family. | Peptidoglycan glycosyltransferase; PFAM: penicillin-binding protein transpeptidase; PASTA domain containing protein; KEGG: tma:TM0870 penicillin-binding protein 2. | 0.952 |
Tlet_0638 | Tlet_1784 | Tlet_0638 | Tlet_1784 | PFAM: cell cycle protein; KEGG: tma:TM0233 cell division protein, RodA/FtsW/spoVE family; Belongs to the SEDS family. | UDP-N-acetylmuramoylalanyl-D-glutamyl-2, 6-diaminopimelate--D-alanyl-D-alanyl ligase; Involved in cell wall formation. Catalyzes the final step in the synthesis of UDP-N-acetylmuramoyl-pentapeptide, the precursor of murein. | 0.881 |
Tlet_0638 | mraY | Tlet_0638 | Tlet_1785 | PFAM: cell cycle protein; KEGG: tma:TM0233 cell division protein, RodA/FtsW/spoVE family; Belongs to the SEDS family. | phospho-N-acetylmuramoyl-pentapeptide- transferase; First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan; Belongs to the glycosyltransferase 4 family. MraY subfamily. | 0.893 |
Tlet_0638 | murB | Tlet_0638 | Tlet_0539 | PFAM: cell cycle protein; KEGG: tma:TM0233 cell division protein, RodA/FtsW/spoVE family; Belongs to the SEDS family. | UDP-N-acetylenolpyruvoylglucosamine reductase; Cell wall formation. | 0.579 |
Tlet_0638 | murC | Tlet_0638 | Tlet_0640 | PFAM: cell cycle protein; KEGG: tma:TM0233 cell division protein, RodA/FtsW/spoVE family; Belongs to the SEDS family. | UDP-N-acetylmuramate--alanine ligase; Cell wall formation; Belongs to the MurCDEF family. | 0.982 |
Tlet_0638 | murD | Tlet_0638 | Tlet_0637 | PFAM: cell cycle protein; KEGG: tma:TM0233 cell division protein, RodA/FtsW/spoVE family; Belongs to the SEDS family. | UDP-N-acetylmuramoylalanine--D-glutamate ligase; Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA). Belongs to the MurCDEF family. | 0.978 |
Tlet_0638 | murE | Tlet_0638 | Tlet_1783 | PFAM: cell cycle protein; KEGG: tma:TM0233 cell division protein, RodA/FtsW/spoVE family; Belongs to the SEDS family. | UDP-N-acetylmuramyl-tripeptide synthetase; Catalyzes the addition of an amino acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan. | 0.798 |
Tlet_0638 | murG | Tlet_0638 | Tlet_0639 | PFAM: cell cycle protein; KEGG: tma:TM0233 cell division protein, RodA/FtsW/spoVE family; Belongs to the SEDS family. | Undecaprenyldiphospho-muramoylpentapeptide beta-N-acetylglucosaminyltransferase; Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II); Belongs to the glycosyltransferase 28 family. MurG subfamily. | 0.982 |
Tlet_0638 | murI | Tlet_0638 | Tlet_0524 | PFAM: cell cycle protein; KEGG: tma:TM0233 cell division protein, RodA/FtsW/spoVE family; Belongs to the SEDS family. | Glutamate racemase; Provides the (R)-glutamate required for cell wall biosynthesis. | 0.441 |
Tlet_1434 | Tlet_0638 | Tlet_1434 | Tlet_0638 | Peptidoglycan glycosyltransferase; PFAM: penicillin-binding protein transpeptidase; PASTA domain containing protein; KEGG: tma:TM0870 penicillin-binding protein 2. | PFAM: cell cycle protein; KEGG: tma:TM0233 cell division protein, RodA/FtsW/spoVE family; Belongs to the SEDS family. | 0.952 |
Tlet_1434 | Tlet_1784 | Tlet_1434 | Tlet_1784 | Peptidoglycan glycosyltransferase; PFAM: penicillin-binding protein transpeptidase; PASTA domain containing protein; KEGG: tma:TM0870 penicillin-binding protein 2. | UDP-N-acetylmuramoylalanyl-D-glutamyl-2, 6-diaminopimelate--D-alanyl-D-alanyl ligase; Involved in cell wall formation. Catalyzes the final step in the synthesis of UDP-N-acetylmuramoyl-pentapeptide, the precursor of murein. | 0.822 |
Tlet_1434 | mraY | Tlet_1434 | Tlet_1785 | Peptidoglycan glycosyltransferase; PFAM: penicillin-binding protein transpeptidase; PASTA domain containing protein; KEGG: tma:TM0870 penicillin-binding protein 2. | phospho-N-acetylmuramoyl-pentapeptide- transferase; First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan; Belongs to the glycosyltransferase 4 family. MraY subfamily. | 0.865 |
Tlet_1434 | murB | Tlet_1434 | Tlet_0539 | Peptidoglycan glycosyltransferase; PFAM: penicillin-binding protein transpeptidase; PASTA domain containing protein; KEGG: tma:TM0870 penicillin-binding protein 2. | UDP-N-acetylenolpyruvoylglucosamine reductase; Cell wall formation. | 0.537 |
Tlet_1434 | murC | Tlet_1434 | Tlet_0640 | Peptidoglycan glycosyltransferase; PFAM: penicillin-binding protein transpeptidase; PASTA domain containing protein; KEGG: tma:TM0870 penicillin-binding protein 2. | UDP-N-acetylmuramate--alanine ligase; Cell wall formation; Belongs to the MurCDEF family. | 0.829 |
Tlet_1434 | murD | Tlet_1434 | Tlet_0637 | Peptidoglycan glycosyltransferase; PFAM: penicillin-binding protein transpeptidase; PASTA domain containing protein; KEGG: tma:TM0870 penicillin-binding protein 2. | UDP-N-acetylmuramoylalanine--D-glutamate ligase; Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA). Belongs to the MurCDEF family. | 0.868 |
Tlet_1434 | murE | Tlet_1434 | Tlet_1783 | Peptidoglycan glycosyltransferase; PFAM: penicillin-binding protein transpeptidase; PASTA domain containing protein; KEGG: tma:TM0870 penicillin-binding protein 2. | UDP-N-acetylmuramyl-tripeptide synthetase; Catalyzes the addition of an amino acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan. | 0.884 |
Tlet_1434 | murG | Tlet_1434 | Tlet_0639 | Peptidoglycan glycosyltransferase; PFAM: penicillin-binding protein transpeptidase; PASTA domain containing protein; KEGG: tma:TM0870 penicillin-binding protein 2. | Undecaprenyldiphospho-muramoylpentapeptide beta-N-acetylglucosaminyltransferase; Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II); Belongs to the glycosyltransferase 28 family. MurG subfamily. | 0.810 |
Tlet_1434 | murI | Tlet_1434 | Tlet_0524 | Peptidoglycan glycosyltransferase; PFAM: penicillin-binding protein transpeptidase; PASTA domain containing protein; KEGG: tma:TM0870 penicillin-binding protein 2. | Glutamate racemase; Provides the (R)-glutamate required for cell wall biosynthesis. | 0.427 |
Tlet_1784 | Tlet_0638 | Tlet_1784 | Tlet_0638 | UDP-N-acetylmuramoylalanyl-D-glutamyl-2, 6-diaminopimelate--D-alanyl-D-alanyl ligase; Involved in cell wall formation. Catalyzes the final step in the synthesis of UDP-N-acetylmuramoyl-pentapeptide, the precursor of murein. | PFAM: cell cycle protein; KEGG: tma:TM0233 cell division protein, RodA/FtsW/spoVE family; Belongs to the SEDS family. | 0.881 |
Tlet_1784 | Tlet_1434 | Tlet_1784 | Tlet_1434 | UDP-N-acetylmuramoylalanyl-D-glutamyl-2, 6-diaminopimelate--D-alanyl-D-alanyl ligase; Involved in cell wall formation. Catalyzes the final step in the synthesis of UDP-N-acetylmuramoyl-pentapeptide, the precursor of murein. | Peptidoglycan glycosyltransferase; PFAM: penicillin-binding protein transpeptidase; PASTA domain containing protein; KEGG: tma:TM0870 penicillin-binding protein 2. | 0.822 |