STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
ldhBL-lactate dehydrogenase; Catalyzes the conversion of lactate to pyruvate. Belongs to the LDH/MDH superfamily. LDH family. (314 aa)    
Predicted Functional Partners:
pfl
Pyruvate formate-lyase; High confidence in function and specificity.
   
 
 0.991
pyk
Pyk protein; High confidence in function and specificity; Belongs to the pyruvate kinase family.
  
 0.991
nifJ
NifJ protein; Pyruvate:ferredoxin (flavodoxin) oxidoreductase, Thiamine pyrophosphate enzyme, C-terminal TPP binding domain, pyruv_ox_red: pyruvate:ferredoxin (flavodoxin) oxidoreductase; High confidence in function and specificity.
  
 
 0.980
pycA
Pyruvate carboxylase; Catalyzes a 2-step reaction, involving the ATP-dependent carboxylation of the covalently attached biotin in the first step and the transfer of the carboxyl group to pyruvate in the second.
  
 0.960
pgiA
PgiA protein; PF00342: Phosphoglucose isomerase; High confidence in function and specificity; Belongs to the GPI family.
  
 
 0.957
poxL
Pyruvate oxidase; PF02776: Thiamine pyrophosphate enzyme, N-terminal TPP binding domain, TIGR00118: acetolactate synthase, large subunit, biosynthetic type; High confidence in function and specificity.
  
 0.950
gapB
TIGR01534: Glyceraldehyde-3-phosphate dehydrogenase, type I, PF02800: Glyceraldehyde 3-phosphate dehydrogenase, C-terminal domain; High confidence in function and specificity; Belongs to the glyceraldehyde-3-phosphate dehydrogenase family.
  
 
 0.947
gapA
Glyceraldehyde-3-phosphate dehydrogenase, type I; High confidence in function and specificity; Belongs to the glyceraldehyde-3-phosphate dehydrogenase family.
  
 
 0.932
mleS
Malolactic enzyme; High confidence in function and specificity.
  
 0.930
pdhB
Pyruvate dehydrogenase E1 component beta subunit; 1-deoxy-D-xylulose-5-phosphate synthase (DXP synthase); High confidence in function and specificity.
   
 0.923
Your Current Organism:
Lactococcus lactis
NCBI taxonomy Id: 416870
Other names: L. lactis subsp. cremoris MG1363, Lactococcus lactis subsp. cremoris MG1363, Lactococcus lactis subsp. cremoris str. MG1363, Lactococcus lactis subsp. cremoris strain MG1363
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