STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
some 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
gnd6-phosphogluconate dehydrogenase, decarboxylating; Catalyzes the oxidative decarboxylation of 6- phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH; Belongs to the 6-phosphogluconate dehydrogenase family (472 aa)    
Predicted Functional Partners:
zwf
Glucose-6-phosphate 1-dehydrogenase; Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone
 
 
 0.977
rpiA
Ribose-5-phosphate isomerase A; Catalyzes the reversible conversion of ribose-5- phosphate to ribulose 5-phosphate
  
 
 0.954
llmg_2431
Uncharacterized protein llmg_2431; 3-carboxymuconate cyclase; Belongs to the cycloisomerase 2 family
 
  
 0.945
gntK
Gluconate kinase; PF00370: FGGY family of carbohydrate kinases, N-terminal domain, TIGR01314: gntK_FGGY: gluconate kinase; High confidence in function and specificity; Belongs to the FGGY kinase family
    
 0.940
rpe2
Ribulose-phosphate 3-epimerase; High confidence in function and specificity
  
 0.925
rpe
Ribulose-phosphate 3-epimerase; High confidence in function and specificity; Belongs to the ribulose-phosphate 3-epimerase family
  
 0.925
rpiB
Ribose 5-phosphate isomerase B; High confidence in function and specificity
    
 0.910
gntZ
GntZ protein; PF03446: NAD binding domain of 6-phosphogluconate dehydrogenase, TIGR00872: gnd_rel: 6-phosphogluconate dehydrogenase (decarboxylating); High confidence in function and specificity
  
 
0.833
uxuA
Mannonate dehydratase; Catalyzes the dehydration of D-mannonate; Belongs to the mannonate dehydratase family
     
  0.800
tkt
Transketolase; Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate
  
 
 0.790
Your Current Organism:
Lactococcus lactis cremoris
NCBI taxonomy Id: 416870
Other names: L. lactis subsp. cremoris MG1363, Lactococcus lactis cremoris, Lactococcus lactis subsp. cremoris MG1363, Lactococcus lactis subsp. cremoris str. MG1363, Lactococcus lactis subsp. cremoris strain MG1363
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