node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
carB | pyrB | llmg_1089 | llmg_0893 | Carbamoyl-phosphate synthase, large subunit; Region start changed from 1046934 to 1046961 (-27 bases); Belongs to the CarB family. | Aspartate carbamoyltransferase; High confidence in function and specificity; Belongs to the aspartate/ornithine carbamoyltransferase superfamily. ATCase family. | 0.999 |
carB | pyrC | llmg_1089 | llmg_1508 | Carbamoyl-phosphate synthase, large subunit; Region start changed from 1046934 to 1046961 (-27 bases); Belongs to the CarB family. | Putative dihydroorotase; Catalyzes the reversible cyclization of carbamoyl aspartate to dihydroorotate; Belongs to the metallo-dependent hydrolases superfamily. DHOase family. Class I DHOase subfamily. | 0.994 |
carB | pyrE | llmg_1089 | llmg_1509 | Carbamoyl-phosphate synthase, large subunit; Region start changed from 1046934 to 1046961 (-27 bases); Belongs to the CarB family. | PyrE protein; Catalyzes the transfer of a ribosyl phosphate group from 5- phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP). | 0.932 |
carB | pyrF | llmg_1089 | llmg_1107 | Carbamoyl-phosphate synthase, large subunit; Region start changed from 1046934 to 1046961 (-27 bases); Belongs to the CarB family. | Orotidine-phosphate decarboxylase; Catalyzes the decarboxylation of orotidine 5'-monophosphate (OMP) to uridine 5'-monophosphate (UMP); Belongs to the OMP decarboxylase family. Type 1 subfamily. | 0.915 |
carB | pyrH | llmg_1089 | llmg_2285 | Carbamoyl-phosphate synthase, large subunit; Region start changed from 1046934 to 1046961 (-27 bases); Belongs to the CarB family. | PyrH protein; Catalyzes the reversible phosphorylation of UMP to UDP. | 0.441 |
carB | pyrK | llmg_1089 | llmg_1105 | Carbamoyl-phosphate synthase, large subunit; Region start changed from 1046934 to 1046961 (-27 bases); Belongs to the CarB family. | Dihydroorotate dehydrogenase, electron transfer subunit; Responsible for channeling the electrons from the oxidation of dihydroorotate from the FMN redox center in the PyrDB subunit to the ultimate electron acceptor NAD(+). | 0.920 |
carB | pyrP | llmg_1089 | llmg_0891 | Carbamoyl-phosphate synthase, large subunit; Region start changed from 1046934 to 1046961 (-27 bases); Belongs to the CarB family. | Uracil permease (Uracil transporter); High confidence in function and specificity. | 0.801 |
carB | pyrR | llmg_1089 | llmg_0890 | Carbamoyl-phosphate synthase, large subunit; Region start changed from 1046934 to 1046961 (-27 bases); Belongs to the CarB family. | Pyrimidine operon attenuation protein / uracil phosphoribosyltransferase; Regulates transcriptional attenuation of the pyrimidine nucleotide (pyr) operon in response to exogenous pyrimidines, probably by binding to specific sites on pyr mRNA. This probably disrupts an antiterminator hairpin in the RNA and favors formation of a downstream transcription terminator, leading to a reduced expression of downstream genes. | 0.848 |
carB | upp | llmg_1089 | llmg_2176 | Carbamoyl-phosphate synthase, large subunit; Region start changed from 1046934 to 1046961 (-27 bases); Belongs to the CarB family. | Upp protein; Catalyzes the conversion of uracil and 5-phospho-alpha-D- ribose 1-diphosphate (PRPP) to UMP and diphosphate. | 0.534 |
pyrB | carB | llmg_0893 | llmg_1089 | Aspartate carbamoyltransferase; High confidence in function and specificity; Belongs to the aspartate/ornithine carbamoyltransferase superfamily. ATCase family. | Carbamoyl-phosphate synthase, large subunit; Region start changed from 1046934 to 1046961 (-27 bases); Belongs to the CarB family. | 0.999 |
pyrB | pyrC | llmg_0893 | llmg_1508 | Aspartate carbamoyltransferase; High confidence in function and specificity; Belongs to the aspartate/ornithine carbamoyltransferase superfamily. ATCase family. | Putative dihydroorotase; Catalyzes the reversible cyclization of carbamoyl aspartate to dihydroorotate; Belongs to the metallo-dependent hydrolases superfamily. DHOase family. Class I DHOase subfamily. | 0.999 |
pyrB | pyrE | llmg_0893 | llmg_1509 | Aspartate carbamoyltransferase; High confidence in function and specificity; Belongs to the aspartate/ornithine carbamoyltransferase superfamily. ATCase family. | PyrE protein; Catalyzes the transfer of a ribosyl phosphate group from 5- phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP). | 0.981 |
pyrB | pyrF | llmg_0893 | llmg_1107 | Aspartate carbamoyltransferase; High confidence in function and specificity; Belongs to the aspartate/ornithine carbamoyltransferase superfamily. ATCase family. | Orotidine-phosphate decarboxylase; Catalyzes the decarboxylation of orotidine 5'-monophosphate (OMP) to uridine 5'-monophosphate (UMP); Belongs to the OMP decarboxylase family. Type 1 subfamily. | 0.984 |
pyrB | pyrH | llmg_0893 | llmg_2285 | Aspartate carbamoyltransferase; High confidence in function and specificity; Belongs to the aspartate/ornithine carbamoyltransferase superfamily. ATCase family. | PyrH protein; Catalyzes the reversible phosphorylation of UMP to UDP. | 0.700 |
pyrB | pyrK | llmg_0893 | llmg_1105 | Aspartate carbamoyltransferase; High confidence in function and specificity; Belongs to the aspartate/ornithine carbamoyltransferase superfamily. ATCase family. | Dihydroorotate dehydrogenase, electron transfer subunit; Responsible for channeling the electrons from the oxidation of dihydroorotate from the FMN redox center in the PyrDB subunit to the ultimate electron acceptor NAD(+). | 0.890 |
pyrB | pyrP | llmg_0893 | llmg_0891 | Aspartate carbamoyltransferase; High confidence in function and specificity; Belongs to the aspartate/ornithine carbamoyltransferase superfamily. ATCase family. | Uracil permease (Uracil transporter); High confidence in function and specificity. | 0.992 |
pyrB | pyrR | llmg_0893 | llmg_0890 | Aspartate carbamoyltransferase; High confidence in function and specificity; Belongs to the aspartate/ornithine carbamoyltransferase superfamily. ATCase family. | Pyrimidine operon attenuation protein / uracil phosphoribosyltransferase; Regulates transcriptional attenuation of the pyrimidine nucleotide (pyr) operon in response to exogenous pyrimidines, probably by binding to specific sites on pyr mRNA. This probably disrupts an antiterminator hairpin in the RNA and favors formation of a downstream transcription terminator, leading to a reduced expression of downstream genes. | 0.999 |
pyrB | upp | llmg_0893 | llmg_2176 | Aspartate carbamoyltransferase; High confidence in function and specificity; Belongs to the aspartate/ornithine carbamoyltransferase superfamily. ATCase family. | Upp protein; Catalyzes the conversion of uracil and 5-phospho-alpha-D- ribose 1-diphosphate (PRPP) to UMP and diphosphate. | 0.591 |
pyrC | carB | llmg_1508 | llmg_1089 | Putative dihydroorotase; Catalyzes the reversible cyclization of carbamoyl aspartate to dihydroorotate; Belongs to the metallo-dependent hydrolases superfamily. DHOase family. Class I DHOase subfamily. | Carbamoyl-phosphate synthase, large subunit; Region start changed from 1046934 to 1046961 (-27 bases); Belongs to the CarB family. | 0.994 |
pyrC | pyrB | llmg_1508 | llmg_0893 | Putative dihydroorotase; Catalyzes the reversible cyclization of carbamoyl aspartate to dihydroorotate; Belongs to the metallo-dependent hydrolases superfamily. DHOase family. Class I DHOase subfamily. | Aspartate carbamoyltransferase; High confidence in function and specificity; Belongs to the aspartate/ornithine carbamoyltransferase superfamily. ATCase family. | 0.999 |