node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
glpD | menB | llmg_1098 | llmg_1831 | GlpD protein; High confidence in function and specificity. | Naphthoate synthase; Converts o-succinylbenzoyl-CoA (OSB-CoA) to 1,4-dihydroxy-2- naphthoyl-CoA (DHNA-CoA). | 0.599 |
glpD | menD | llmg_1098 | llmg_1829 | GlpD protein; High confidence in function and specificity. | 2-oxoglutarate decarboxylase / 2-succinyl-6-hydroxy-2,4-cyclohexadiene-1-carboxylate synthase; Catalyzes the thiamine diphosphate-dependent decarboxylation of 2-oxoglutarate and the subsequent addition of the resulting succinic semialdehyde-thiamine pyrophosphate anion to isochorismate to yield 2- succinyl-5-enolpyruvyl-6-hydroxy-3-cyclohexene-1-carboxylate (SEPHCHC). | 0.701 |
glpD | ubiE | llmg_1098 | llmg_0753 | GlpD protein; High confidence in function and specificity. | Ubiquinone/menaquinone biosynthesis methyltransferase; Methyltransferase required for the conversion of demethylmenaquinol (DMKH2) to menaquinol (MKH2). | 0.472 |
ispA | menB | llmg_1689 | llmg_1831 | Geranyltranstransferase; Farnesyltranstransferase, EC 2.5.1.29; High confidence in function and specificity; Belongs to the FPP/GGPP synthase family. | Naphthoate synthase; Converts o-succinylbenzoyl-CoA (OSB-CoA) to 1,4-dihydroxy-2- naphthoyl-CoA (DHNA-CoA). | 0.736 |
ispA | menD | llmg_1689 | llmg_1829 | Geranyltranstransferase; Farnesyltranstransferase, EC 2.5.1.29; High confidence in function and specificity; Belongs to the FPP/GGPP synthase family. | 2-oxoglutarate decarboxylase / 2-succinyl-6-hydroxy-2,4-cyclohexadiene-1-carboxylate synthase; Catalyzes the thiamine diphosphate-dependent decarboxylation of 2-oxoglutarate and the subsequent addition of the resulting succinic semialdehyde-thiamine pyrophosphate anion to isochorismate to yield 2- succinyl-5-enolpyruvyl-6-hydroxy-3-cyclohexene-1-carboxylate (SEPHCHC). | 0.680 |
ispA | menF | llmg_1689 | llmg_1828 | Geranyltranstransferase; Farnesyltranstransferase, EC 2.5.1.29; High confidence in function and specificity; Belongs to the FPP/GGPP synthase family. | Menaquinone-specific isochorismate synthase; High confidence in function and specificity. | 0.751 |
ispA | noxB | llmg_1689 | llmg_1734 | Geranyltranstransferase; Farnesyltranstransferase, EC 2.5.1.29; High confidence in function and specificity; Belongs to the FPP/GGPP synthase family. | NADH dehydrogenase; High confidence in function and specificity. | 0.683 |
llmg_1834 | menB | llmg_1834 | llmg_1831 | Conserved hypothetical protein; Phenylacetic acid degradation-related protein. | Naphthoate synthase; Converts o-succinylbenzoyl-CoA (OSB-CoA) to 1,4-dihydroxy-2- naphthoyl-CoA (DHNA-CoA). | 0.862 |
llmg_1834 | menD | llmg_1834 | llmg_1829 | Conserved hypothetical protein; Phenylacetic acid degradation-related protein. | 2-oxoglutarate decarboxylase / 2-succinyl-6-hydroxy-2,4-cyclohexadiene-1-carboxylate synthase; Catalyzes the thiamine diphosphate-dependent decarboxylation of 2-oxoglutarate and the subsequent addition of the resulting succinic semialdehyde-thiamine pyrophosphate anion to isochorismate to yield 2- succinyl-5-enolpyruvyl-6-hydroxy-3-cyclohexene-1-carboxylate (SEPHCHC). | 0.722 |
llmg_1834 | menE | llmg_1834 | llmg_1832 | Conserved hypothetical protein; Phenylacetic acid degradation-related protein. | O-succinylbenzoic acid--CoA ligase; Converts 2-succinylbenzoate (OSB) to 2-succinylbenzoyl-CoA (OSB-CoA); Belongs to the ATP-dependent AMP-binding enzyme family. MenE subfamily. | 0.503 |
llmg_1834 | menX | llmg_1834 | llmg_1830 | Conserved hypothetical protein; Phenylacetic acid degradation-related protein. | Menaquinone biosynthesis related protein; Catalyzes a proton abstraction reaction that results in 2,5- elimination of pyruvate from 2-succinyl-5-enolpyruvyl-6-hydroxy-3- cyclohexene-1-carboxylate (SEPHCHC) and the formation of 2-succinyl-6- hydroxy-2,4-cyclohexadiene-1-carboxylate (SHCHC). | 0.524 |
menB | glpD | llmg_1831 | llmg_1098 | Naphthoate synthase; Converts o-succinylbenzoyl-CoA (OSB-CoA) to 1,4-dihydroxy-2- naphthoyl-CoA (DHNA-CoA). | GlpD protein; High confidence in function and specificity. | 0.599 |
menB | ispA | llmg_1831 | llmg_1689 | Naphthoate synthase; Converts o-succinylbenzoyl-CoA (OSB-CoA) to 1,4-dihydroxy-2- naphthoyl-CoA (DHNA-CoA). | Geranyltranstransferase; Farnesyltranstransferase, EC 2.5.1.29; High confidence in function and specificity; Belongs to the FPP/GGPP synthase family. | 0.736 |
menB | llmg_1834 | llmg_1831 | llmg_1834 | Naphthoate synthase; Converts o-succinylbenzoyl-CoA (OSB-CoA) to 1,4-dihydroxy-2- naphthoyl-CoA (DHNA-CoA). | Conserved hypothetical protein; Phenylacetic acid degradation-related protein. | 0.862 |
menB | menC | llmg_1831 | llmg_1833 | Naphthoate synthase; Converts o-succinylbenzoyl-CoA (OSB-CoA) to 1,4-dihydroxy-2- naphthoyl-CoA (DHNA-CoA). | O-succinylbenzoate synthase; Converts 2-succinyl-6-hydroxy-2,4-cyclohexadiene-1- carboxylate (SHCHC) to 2-succinylbenzoate (OSB). | 0.910 |
menB | menD | llmg_1831 | llmg_1829 | Naphthoate synthase; Converts o-succinylbenzoyl-CoA (OSB-CoA) to 1,4-dihydroxy-2- naphthoyl-CoA (DHNA-CoA). | 2-oxoglutarate decarboxylase / 2-succinyl-6-hydroxy-2,4-cyclohexadiene-1-carboxylate synthase; Catalyzes the thiamine diphosphate-dependent decarboxylation of 2-oxoglutarate and the subsequent addition of the resulting succinic semialdehyde-thiamine pyrophosphate anion to isochorismate to yield 2- succinyl-5-enolpyruvyl-6-hydroxy-3-cyclohexene-1-carboxylate (SEPHCHC). | 0.993 |
menB | menE | llmg_1831 | llmg_1832 | Naphthoate synthase; Converts o-succinylbenzoyl-CoA (OSB-CoA) to 1,4-dihydroxy-2- naphthoyl-CoA (DHNA-CoA). | O-succinylbenzoic acid--CoA ligase; Converts 2-succinylbenzoate (OSB) to 2-succinylbenzoyl-CoA (OSB-CoA); Belongs to the ATP-dependent AMP-binding enzyme family. MenE subfamily. | 0.998 |
menB | menF | llmg_1831 | llmg_1828 | Naphthoate synthase; Converts o-succinylbenzoyl-CoA (OSB-CoA) to 1,4-dihydroxy-2- naphthoyl-CoA (DHNA-CoA). | Menaquinone-specific isochorismate synthase; High confidence in function and specificity. | 0.786 |
menB | menX | llmg_1831 | llmg_1830 | Naphthoate synthase; Converts o-succinylbenzoyl-CoA (OSB-CoA) to 1,4-dihydroxy-2- naphthoyl-CoA (DHNA-CoA). | Menaquinone biosynthesis related protein; Catalyzes a proton abstraction reaction that results in 2,5- elimination of pyruvate from 2-succinyl-5-enolpyruvyl-6-hydroxy-3- cyclohexene-1-carboxylate (SEPHCHC) and the formation of 2-succinyl-6- hydroxy-2,4-cyclohexadiene-1-carboxylate (SHCHC). | 0.973 |
menB | noxB | llmg_1831 | llmg_1734 | Naphthoate synthase; Converts o-succinylbenzoyl-CoA (OSB-CoA) to 1,4-dihydroxy-2- naphthoyl-CoA (DHNA-CoA). | NADH dehydrogenase; High confidence in function and specificity. | 0.728 |