STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
pbp2APenicillin-binding protein 2a; PF00912: Transglycosylase; High confidence in function and specificity. (743 aa)    
Predicted Functional Partners:
pbp2B
Penicillin-binding protein 2B; High confidence in function and specificity.
 
 
 0.998
pbpX
Penicillin-binding protein; High confidence in function and specificity.
 
 
 0.992
rodA
Rod shape-determining protein RodA; Cell cycle protein; High confidence in function and specificity; Belongs to the SEDS family.
  
 
 
 0.952
pbp1B
Penicillin-binding protein 1B; High confidence in function and specificity.
  
  
0.951
dacB
DacB protein; High confidence in function and specificity.
     
 0.945
mreC
Cell shape determining protein mreC; Involved in formation and maintenance of cell shape.
  
 
 0.943
ponA
Putative penicillin-binding protein 1a; Includes: Penicillin- insensitive transglycosylase (EC 2.4.2.-) (Peptidoglycan TGase); Penicillin-sensitive transpeptidase (EC 3.4.-.-) (DD-transpeptidase)]., PBP_1a_fam: penicillin-binding protein, 1A family; High confidence in function and specificity.
  
  
 
0.927
dacA
DacA protein; D-alanyl-D-alanine carboxypeptidase precursor, PF00768: D-alanyl-D-alanine carboxypeptidase; High confidence in function and specificity; Belongs to the peptidase S11 family.
  
 
 0.913
ftsA
Cell division protein ftsA; Cell division protein that is involved in the assembly of the Z ring. May serve as a membrane anchor for the Z ring. Belongs to the FtsA/MreB family.
  
   
 0.863
ftsZ
Cell division protein ftsZ; Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity.
  
   
 0.841
Your Current Organism:
Lactococcus lactis
NCBI taxonomy Id: 416870
Other names: L. lactis subsp. cremoris MG1363, Lactococcus lactis subsp. cremoris MG1363, Lactococcus lactis subsp. cremoris str. MG1363, Lactococcus lactis subsp. cremoris strain MG1363
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.