STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
jhhlp_000914Uncharacterized protein. (441 aa)    
Predicted Functional Partners:
jhhlp_000011
DNA repair protein rad9; Acts in DNA repair and mutagenesis. Involved in promoting resistance to ionizing radiation and UV light, as well as regulating cell cycle progression after irradiation.
    
 0.999
jhhlp_002564
3'-5' exonuclease domain-containing protein.
   
 0.991
jhhlp_007278
Uncharacterized protein.
   
 0.990
jhhlp_007380
AAA domain-containing protein.
   
 0.989
jhhlp_008105
AAA domain-containing protein; Belongs to the type-B carboxylesterase/lipase family.
   
 0.979
jhhlp_002494
Checkpoint protein; Belongs to the HUS1 family.
    
 0.979
jhhlp_006607
AAA domain-containing protein.
   
 0.977
jhhlp_005509
AAA domain-containing protein.
   
 0.974
jhhlp_006603
Uncharacterized protein.
    
 0.974
FEN1
Flap endonuclease 1; Structure-specific nuclease with 5'-flap endonuclease and 5'- 3' exonuclease activities involved in DNA replication and repair. During DNA replication, cleaves the 5'-overhanging flap structure that is generated by displacement synthesis when DNA polymerase encounters the 5'-end of a downstream Okazaki fragment. It enters the flap from the 5'-end and then tracks to cleave the flap base, leaving a nick for ligation. Also involved in the long patch base excision repair (LP-BER) pathway, by cleaving within the apurinic/apyrimidinic (AP) site- terminated flap. Acts as [...]
   
 0.945
Your Current Organism:
Lomentospora prolificans
NCBI taxonomy Id: 41688
Other names: CBS 467.74, IMI 188615, L. prolificans, MUCL 18141, Scedosporium inflatum, Scedosporium prolificans
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