STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
Maeo_0138PFAM: AMMECR1 domain protein; KEGG: mja:MJ0810 hypothetical protein. (199 aa)    
Predicted Functional Partners:
Maeo_1383
PFAM: protein of unknown function DUF52; KEGG: mja:MJ0403 hypothetical protein; Belongs to the MEMO1 family.
    0.991
Maeo_1055
PFAM: Radical SAM domain protein; KEGG: mja:MJ0808 pyruvate formate-lyase activating enzyme.
     0.950
Maeo_0139
PFAM: phosphoesterase RecJ domain protein; phosphoesterase DHHA1; KEGG: mmp:MMP0547 RecJ related protein.
       0.537
hisG
ATP phosphoribosyltransferase; Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of HisG enzymatic activity. Belongs to the ATP phosphoribosyltransferase family. Long subfamily.
       0.527
Maeo_1054
PFAM: protein of unknown function DUF98; KEGG: mja:MJ0807 hypothetical protein.
       0.424
Maeo_0034
TIGRFAM: Acetyl coenzyme A synthetase (ADP forming) alpha domain; PFAM: CoA-binding domain protein; KEGG: mja:MJ0590 hypothetical protein.
       0.422
Your Current Organism:
Methanococcus aeolicus
NCBI taxonomy Id: 419665
Other names: M. aeolicus Nankai-3, Methanococcus aeolicus Nankai-3, Methanococcus aeolicus str. Nankai-3, Methanococcus aeolicus strain Nankai-3
Server load: low (24%) [HD]