STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
mfnBProtein of unknown function DUF556; Catalyzes the formation of 4-(hydroxymethyl)-2- furancarboxaldehyde phosphate (4-HFC-P) from two molecules of glyceraldehyde-3-P (GA-3-P). (235 aa)    
Predicted Functional Partners:
Maeo_1384
PFAM: aspartate/glutamate/uridylate kinase; KEGG: mmp:MMP1399 aspartate/glutamate/uridylate kinase.
 
   
 0.933
Maeo_0623
PFAM: Hydantoinase/oxoprolinase; KEGG: mja:MJ0840 hypothetical protein.
 
   
 0.920
Maeo_0605
TIGRFAM: dihydropteroate synthase-related protein; PFAM: dihydropteroate synthase DHPS; KEGG: mja:MJ0107 dihydropteroate synthase.
 
   
 0.913
Maeo_0448
PFAM: protein of unknown function DUF201; KEGG: mja:MJ0815 hypothetical protein.
 
   
 0.910
Maeo_1218
TIGRFAM: hisA/hisF family protein; PFAM: histidine biosynthesis protein; KEGG: mmp:MMP1690 similar to phosphoribosylformimino-5-aminoimidazole carboxamide ribotide isomerase.
 
   
 0.847
Maeo_0083
PFAM: Amidohydrolase 3; KEGG: mbu:Mbur_0284 formylmethanofuran dehydrogenase subunit A.
 
   
 0.806
Maeo_1443
PFAM: Amidohydrolase 3; KEGG: mth:MTH1557 tungsten formylmethanofuran dehydrogenase, subunit A.
 
   
 0.805
ftr
Formylmethanofuran--tetrahydromethanopterin N-formyltransferase; Catalyzes the reversible transfer of a formyl group from formylmethanofuran (formyl-MFR) to tetrahydromethanopterin (H(4)MPT) so as to produce 5-formyl tetrahydromethanopterin (5-formyl-H(4)MPT) and methanofuran (MFR); Belongs to the FTR family.
 
     0.785
Maeo_1295
PFAM: triphosphoribosyl-dephospho-CoA protein; KEGG: mmp:MMP0213 triphosphoribosyl-dephospho-CoA synthetase related protein.
 
   
 0.775
mch
Methenyltetrahydromethanopterin cyclohydrolase; Catalyzes the reversible interconversion of 5-formyl-H(4)MPT to methenyl-H(4)MPT(+); Belongs to the MCH family.
 
     0.773
Your Current Organism:
Methanococcus aeolicus
NCBI taxonomy Id: 419665
Other names: M. aeolicus Nankai-3, Methanococcus aeolicus Nankai-3, Methanococcus aeolicus str. Nankai-3, Methanococcus aeolicus strain Nankai-3
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