STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
trmYProtein of unknown function DUF358; Specifically catalyzes the N1-methylation of pseudouridine at position 54 (Psi54) in tRNAs; Belongs to the methyltransferase superfamily. TrmY family. (204 aa)    
Predicted Functional Partners:
pus10
THUMP domain protein; Responsible for synthesis of pseudouridine from uracil-54 and uracil-55 in the psi GC loop of transfer RNAs.
 
   
 0.999
Maeo_0668
PFAM: Protein of unknown function UPF0254; KEGG: mmp:MMP0935 hypothetical protein; Belongs to the UPF0254 family.
       0.773
Maeo_0071
TIGRFAM: RNA methyltransferase, TrmH family, group 1; PFAM: tRNA/rRNA methyltransferase (SpoU); KEGG: mmp:MMP0334 rRNA methyltransferase related protein.
     
 0.747
flpA
Non-specific serine/threonine protein kinase; Involved in pre-rRNA and tRNA processing. Utilizes the methyl donor S-adenosyl-L-methionine to catalyze the site-specific 2'-hydroxyl methylation of ribose moieties in rRNA and tRNA. Site specificity is provided by a guide RNA that base pairs with the substrate. Methylation occurs at a characteristic distance from the sequence involved in base pairing with the guide RNA; Belongs to the methyltransferase superfamily. Fibrillarin family.
     
 0.741
Maeo_0268
PFAM: type II secretion system protein; KEGG: mmp:MMP1676 flagella accessory protein J.
 
    0.693
Maeo_0267
PFAM: type II secretion system protein E; KEGG: mmp:MMP1675 flagella accessory protein I.
  
    0.675
Maeo_0256
Flagellin protein; Flagellin is the subunit protein which polymerizes to form the filaments of archaeal flagella.
 
    0.658
Maeo_0264
PFAM: Archaeal flagellar protein F; KEGG: mmp:MMP1672 flagella accessory protein F.
  
    0.654
Maeo_1289
KEGG: mmp:MMP1499 hypothetical protein.
  
     0.640
Maeo_0259
Flagellin protein; Flagellin is the subunit protein which polymerizes to form the filaments of archaeal flagella.
 
    0.633
Your Current Organism:
Methanococcus aeolicus
NCBI taxonomy Id: 419665
Other names: M. aeolicus Nankai-3, Methanococcus aeolicus Nankai-3, Methanococcus aeolicus str. Nankai-3, Methanococcus aeolicus strain Nankai-3
Server load: low (40%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.