node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
Maeo_0345 | Maeo_0653 | Maeo_0345 | Maeo_0653 | PFAM: nucleic acid binding OB-fold tRNA/helicase-type; KEGG: mmp:MMP1032 replication protein A. | TIGRFAM: DNA polymerase Pol2; PFAM: DNA polymerase B exonuclease; DNA polymerase B region; SMART: DNA-directed DNA polymerase B; KEGG: mmp:MMP0380 DNA polymerase family B. | 0.927 |
Maeo_0345 | Maeo_1312 | Maeo_0345 | Maeo_1312 | PFAM: nucleic acid binding OB-fold tRNA/helicase-type; KEGG: mmp:MMP1032 replication protein A. | PFAM: Replication factor C; SMART: Hedgehog/intein hint domain protein; AAA ATPase; KEGG: mja:MJ1422 activator 1 (replication factor C), 35 KD subunit. | 0.923 |
Maeo_0345 | fen | Maeo_0345 | Maeo_1492 | PFAM: nucleic acid binding OB-fold tRNA/helicase-type; KEGG: mmp:MMP1032 replication protein A. | XPG I; Structure-specific nuclease with 5'-flap endonuclease and 5'- 3' exonuclease activities involved in DNA replication and repair. During DNA replication, cleaves the 5'-overhanging flap structure that is generated by displacement synthesis when DNA polymerase encounters the 5'-end of a downstream Okazaki fragment. Binds the unpaired 3'-DNA end and kinks the DNA to facilitate 5' cleavage specificity. Cleaves one nucleotide into the double-stranded DNA from the junction in flap DNA, leaving a nick for ligation. Also involved in the base excision repair (BER) pathway. Acts as a genom [...] | 0.797 |
Maeo_0345 | lig | Maeo_0345 | Maeo_0864 | PFAM: nucleic acid binding OB-fold tRNA/helicase-type; KEGG: mmp:MMP1032 replication protein A. | DNA ligase I, ATP-dependent Dnl1; DNA ligase that seals nicks in double-stranded DNA during DNA replication, DNA recombination and DNA repair. | 0.795 |
Maeo_0345 | pcn | Maeo_0345 | Maeo_0699 | PFAM: nucleic acid binding OB-fold tRNA/helicase-type; KEGG: mmp:MMP1032 replication protein A. | Proliferating cell nuclear antigen PcnA; Sliding clamp subunit that acts as a moving platform for DNA processing. Responsible for tethering the catalytic subunit of DNA polymerase and other proteins to DNA during high-speed replication. Belongs to the PCNA family. | 0.985 |
Maeo_0345 | polB | Maeo_0345 | Maeo_1166 | PFAM: nucleic acid binding OB-fold tRNA/helicase-type; KEGG: mmp:MMP1032 replication protein A. | DNA-directed DNA polymerase; Possesses two activities: a DNA synthesis (polymerase) and an exonucleolytic activity that degrades single-stranded DNA in the 3' to 5' direction. Has a template-primer preference which is characteristic of a replicative DNA polymerase; Belongs to the DNA polymerase delta/II small subunit family. | 0.846 |
Maeo_0345 | polC | Maeo_0345 | Maeo_1141 | PFAM: nucleic acid binding OB-fold tRNA/helicase-type; KEGG: mmp:MMP1032 replication protein A. | DNA polymerase II, large subunit DP2; Possesses two activities: a DNA synthesis (polymerase) and an exonucleolytic activity that degrades single-stranded DNA in the 3'- to 5'-direction. Has a template-primer preference which is characteristic of a replicative DNA polymerase. | 0.475 |
Maeo_0345 | priL | Maeo_0345 | Maeo_1167 | PFAM: nucleic acid binding OB-fold tRNA/helicase-type; KEGG: mmp:MMP1032 replication protein A. | DNA primase, large subunit; Regulatory subunit of DNA primase, an RNA polymerase that catalyzes the synthesis of short RNA molecules used as primers for DNA polymerase during DNA replication. Stabilizes and modulates the activity of the small subunit, increasing the rate of DNA synthesis, and conferring RNA synthesis capability. The DNA polymerase activity may enable DNA primase to also catalyze primer extension after primer synthesis. May also play a role in DNA repair. | 0.845 |
Maeo_0345 | rfcL | Maeo_0345 | Maeo_1361 | PFAM: nucleic acid binding OB-fold tRNA/helicase-type; KEGG: mmp:MMP1032 replication protein A. | AAA ATPase central domain protein; Part of the RFC clamp loader complex which loads the PCNA sliding clamp onto DNA; Belongs to the activator 1 small subunits family. RfcL subfamily. | 0.939 |
Maeo_0345 | rnhB | Maeo_0345 | Maeo_0608 | PFAM: nucleic acid binding OB-fold tRNA/helicase-type; KEGG: mmp:MMP1032 replication protein A. | Ribonuclease HII; Endonuclease that specifically degrades the RNA of RNA-DNA hybrids; Belongs to the RNase HII family. | 0.501 |
Maeo_0653 | Maeo_0345 | Maeo_0653 | Maeo_0345 | TIGRFAM: DNA polymerase Pol2; PFAM: DNA polymerase B exonuclease; DNA polymerase B region; SMART: DNA-directed DNA polymerase B; KEGG: mmp:MMP0380 DNA polymerase family B. | PFAM: nucleic acid binding OB-fold tRNA/helicase-type; KEGG: mmp:MMP1032 replication protein A. | 0.927 |
Maeo_0653 | Maeo_1312 | Maeo_0653 | Maeo_1312 | TIGRFAM: DNA polymerase Pol2; PFAM: DNA polymerase B exonuclease; DNA polymerase B region; SMART: DNA-directed DNA polymerase B; KEGG: mmp:MMP0380 DNA polymerase family B. | PFAM: Replication factor C; SMART: Hedgehog/intein hint domain protein; AAA ATPase; KEGG: mja:MJ1422 activator 1 (replication factor C), 35 KD subunit. | 0.972 |
Maeo_0653 | fen | Maeo_0653 | Maeo_1492 | TIGRFAM: DNA polymerase Pol2; PFAM: DNA polymerase B exonuclease; DNA polymerase B region; SMART: DNA-directed DNA polymerase B; KEGG: mmp:MMP0380 DNA polymerase family B. | XPG I; Structure-specific nuclease with 5'-flap endonuclease and 5'- 3' exonuclease activities involved in DNA replication and repair. During DNA replication, cleaves the 5'-overhanging flap structure that is generated by displacement synthesis when DNA polymerase encounters the 5'-end of a downstream Okazaki fragment. Binds the unpaired 3'-DNA end and kinks the DNA to facilitate 5' cleavage specificity. Cleaves one nucleotide into the double-stranded DNA from the junction in flap DNA, leaving a nick for ligation. Also involved in the base excision repair (BER) pathway. Acts as a genom [...] | 0.991 |
Maeo_0653 | lig | Maeo_0653 | Maeo_0864 | TIGRFAM: DNA polymerase Pol2; PFAM: DNA polymerase B exonuclease; DNA polymerase B region; SMART: DNA-directed DNA polymerase B; KEGG: mmp:MMP0380 DNA polymerase family B. | DNA ligase I, ATP-dependent Dnl1; DNA ligase that seals nicks in double-stranded DNA during DNA replication, DNA recombination and DNA repair. | 0.933 |
Maeo_0653 | pcn | Maeo_0653 | Maeo_0699 | TIGRFAM: DNA polymerase Pol2; PFAM: DNA polymerase B exonuclease; DNA polymerase B region; SMART: DNA-directed DNA polymerase B; KEGG: mmp:MMP0380 DNA polymerase family B. | Proliferating cell nuclear antigen PcnA; Sliding clamp subunit that acts as a moving platform for DNA processing. Responsible for tethering the catalytic subunit of DNA polymerase and other proteins to DNA during high-speed replication. Belongs to the PCNA family. | 0.996 |
Maeo_0653 | polB | Maeo_0653 | Maeo_1166 | TIGRFAM: DNA polymerase Pol2; PFAM: DNA polymerase B exonuclease; DNA polymerase B region; SMART: DNA-directed DNA polymerase B; KEGG: mmp:MMP0380 DNA polymerase family B. | DNA-directed DNA polymerase; Possesses two activities: a DNA synthesis (polymerase) and an exonucleolytic activity that degrades single-stranded DNA in the 3' to 5' direction. Has a template-primer preference which is characteristic of a replicative DNA polymerase; Belongs to the DNA polymerase delta/II small subunit family. | 0.999 |
Maeo_0653 | polC | Maeo_0653 | Maeo_1141 | TIGRFAM: DNA polymerase Pol2; PFAM: DNA polymerase B exonuclease; DNA polymerase B region; SMART: DNA-directed DNA polymerase B; KEGG: mmp:MMP0380 DNA polymerase family B. | DNA polymerase II, large subunit DP2; Possesses two activities: a DNA synthesis (polymerase) and an exonucleolytic activity that degrades single-stranded DNA in the 3'- to 5'-direction. Has a template-primer preference which is characteristic of a replicative DNA polymerase. | 0.618 |
Maeo_0653 | priL | Maeo_0653 | Maeo_1167 | TIGRFAM: DNA polymerase Pol2; PFAM: DNA polymerase B exonuclease; DNA polymerase B region; SMART: DNA-directed DNA polymerase B; KEGG: mmp:MMP0380 DNA polymerase family B. | DNA primase, large subunit; Regulatory subunit of DNA primase, an RNA polymerase that catalyzes the synthesis of short RNA molecules used as primers for DNA polymerase during DNA replication. Stabilizes and modulates the activity of the small subunit, increasing the rate of DNA synthesis, and conferring RNA synthesis capability. The DNA polymerase activity may enable DNA primase to also catalyze primer extension after primer synthesis. May also play a role in DNA repair. | 0.995 |
Maeo_0653 | rfcL | Maeo_0653 | Maeo_1361 | TIGRFAM: DNA polymerase Pol2; PFAM: DNA polymerase B exonuclease; DNA polymerase B region; SMART: DNA-directed DNA polymerase B; KEGG: mmp:MMP0380 DNA polymerase family B. | AAA ATPase central domain protein; Part of the RFC clamp loader complex which loads the PCNA sliding clamp onto DNA; Belongs to the activator 1 small subunits family. RfcL subfamily. | 0.937 |
Maeo_0653 | rnhB | Maeo_0653 | Maeo_0608 | TIGRFAM: DNA polymerase Pol2; PFAM: DNA polymerase B exonuclease; DNA polymerase B region; SMART: DNA-directed DNA polymerase B; KEGG: mmp:MMP0380 DNA polymerase family B. | Ribonuclease HII; Endonuclease that specifically degrades the RNA of RNA-DNA hybrids; Belongs to the RNase HII family. | 0.917 |