STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
mptAProtein of unknown function DUF198; Converts GTP to 7,8-dihydro-D-neopterin 2',3'-cyclic phosphate, the first intermediate in the biosynthesis of coenzyme methanopterin. (309 aa)    
Predicted Functional Partners:
Maeo_0933
TIGRFAM: metal dependent phophohydrolase; PFAM: metal-dependent phosphohydrolase HD sub domain; SMART: metal-dependent phosphohydrolase HD region; KEGG: mmp:MMP0230 hypothetical protein.
  
  
 0.960
Maeo_0632
KEGG: mmp:MMP1250 6-pyruvoyl tetrahydropterin synthase.
 
  
 0.932
moaA
Putative molybdenum cofactor biosynthesis protein A; Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate; Belongs to the radical SAM superfamily. MoaA family.
    
  0.902
Maeo_0544
TIGRFAM: pyruvate kinase; PFAM: Pyruvate kinase barrel; Pyruvate kinase alpha/beta; KEGG: mja:MJ0108 pyruvate kinase; Belongs to the pyruvate kinase family.
 
  
  0.855
Maeo_1041
TIGRFAM: anaerobic ribonucleoside-triphosphate reductase; SMART: Hedgehog/intein hint domain protein; KEGG: mja:MJ0832 hypothetical protein MJ0832.
 
  
  0.830
ndk
Nucleoside-diphosphate kinase; Major role in the synthesis of nucleoside triphosphates other than ATP. The ATP gamma phosphate is transferred to the NDP beta phosphate via a ping-pong mechanism, using a phosphorylated active-site intermediate.
    
  0.807
Maeo_0902
TIGRFAM: putative adenylyl cyclase CyaB; PFAM: adenylate cyclase; KEGG: mmp:MMP1064 RNA-binding region RNP-1 (RNA recognition motif):adenylate cyclase.
    
  0.807
Maeo_1147
PFAM: regulatory protein MarR; regulatory protein ArsR; KEGG: mmp:MMP0033 LysR family member.
     
 0.782
Maeo_1149
PFAM: protein of unknown function DUF201; KEGG: mmp:MMP0035 hypothetical protein.
 
     0.734
tfe
Transcription factor TFIIE, alpha subunit; Transcription factor that plays a role in the activation of archaeal genes transcribed by RNA polymerase. Facilitates transcription initiation by enhancing TATA-box recognition by TATA-box-binding protein (Tbp), and transcription factor B (Tfb) and RNA polymerase recruitment. Not absolutely required for transcription in vitro, but particularly important in cases where Tbp or Tfb function is not optimal. It dynamically alters the nucleic acid-binding properties of RNA polymerases by stabilizing the initiation complex and destabilizing elongatio [...]
       0.687
Your Current Organism:
Methanococcus aeolicus
NCBI taxonomy Id: 419665
Other names: M. aeolicus Nankai-3, Methanococcus aeolicus Nankai-3, Methanococcus aeolicus str. Nankai-3, Methanococcus aeolicus strain Nankai-3
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