STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
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Textmining
[Homology]
Score
dcdDeoxycytidine triphosphate deaminase; Bifunctional enzyme that catalyzes both the deamination of dCTP to dUTP and the hydrolysis of dUTP to dUMP without releasing the toxic dUTP intermediate. (201 aa)    
Predicted Functional Partners:
thyA
Thymidylate synthase; May catalyze the biosynthesis of dTMP using an unknown cosubstrate; Belongs to the thymidylate synthase family. Archaeal-type ThyA subfamily.
  
 
 0.938
ndk
Nucleoside-diphosphate kinase; Major role in the synthesis of nucleoside triphosphates other than ATP. The ATP gamma phosphate is transferred to the NDP beta phosphate via a ping-pong mechanism, using a phosphorylated active-site intermediate.
  
 
 0.936
tmk
dTMP kinase; PFAM: thymidylate kinase; KEGG: mmp:MMP1034 thymidylate kinase.
  
 
 0.936
Maeo_1372
KEGG: mja:MJ1102 deoxycytidine triphosphate deaminase, putative.
  
  
  0.932
Maeo_1041
TIGRFAM: anaerobic ribonucleoside-triphosphate reductase; SMART: Hedgehog/intein hint domain protein; KEGG: mja:MJ0832 hypothetical protein MJ0832.
 
  
 0.926
surE
Stationary-phase survival protein SurE; Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates; Belongs to the SurE nucleotidase family.
    
 0.915
Maeo_1410
Protein of unknown function DUF127; Specifically catalyzes the AdoMet-dependent 2'-O-ribose methylation of cytidine at position 56 in tRNAs; Belongs to the aTrm56 family.
  
    0.684
Maeo_1412
PFAM: protein of unknown function DUF711; KEGG: mmp:MMP1427 hypothetical protein; Belongs to the UPF0210 family.
  
    0.654
Maeo_0381
dTDP-4-dehydrorhamnose reductase; PFAM: NAD-dependent epimerase/dehydratase; polysaccharide biosynthesis protein CapD; dTDP-4-dehydrorhamnose reductase; Male sterility domain; KEGG: mst:Msp_1116 predicted dTDP-4-dehydrorhamnose reductase.
   
    0.621
radB
DNA repair and recombination protein RadB; Involved in DNA repair and in homologous recombination. May regulate the cleavage reactions of the branch-structured DNA. Has a very weak ATPase activity that is not stimulated by DNA. Binds DNA but does not promote DNA strands exchange.
      
 0.544
Your Current Organism:
Methanococcus aeolicus
NCBI taxonomy Id: 419665
Other names: M. aeolicus Nankai-3, Methanococcus aeolicus Nankai-3, Methanococcus aeolicus str. Nankai-3, Methanococcus aeolicus strain Nankai-3
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