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trpB protein (Geobacillus thermodenitrificans) - STRING interaction network
"trpB" - Tryptophan synthase beta chain in Geobacillus thermodenitrificans
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Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
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textmining
co-expression
protein homology
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trpBTryptophan synthase beta chain; The beta subunit is responsible for the synthesis of L- tryptophan from indole and L-serine (404 aa)    
Predicted Functional Partners:
trpA
Tryptophan synthase alpha chain; The alpha subunit is responsible for the aldol cleavage of indoleglycerol phosphate to indole and glyceraldehyde 3- phosphate; Belongs to the TrpA family (268 aa)
  0.999
trpC
annotation not available (258 aa)
 
  0.999
trpF
annotation not available (221 aa)
   
  0.999
trpD
Anthranilate phosphoribosyltransferase; Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5’-phosphoribosyl)-anthranilate (PRA) (339 aa)
   
  0.994
trpE
Anthranilate synthase component 1; Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentr [...] (508 aa)
 
   
  0.969
GTNG_0067
annotation not available (192 aa)
 
   
  0.968
GTNG_1440
annotation not available (402 aa)
   
  0.930
GTNG_0066
annotation not available (473 aa)
 
   
  0.929
glyA
Serine hydroxymethyltransferase; Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism (412 aa)
     
 
  0.922
GTNG_2276
annotation not available (342 aa)
     
  0.922
Your Current Organism:
Geobacillus thermodenitrificans
NCBI taxonomy Id: 420246
Other names: G. thermodenitrificans NG80-2, Geobacillus thermodenitrificans, Geobacillus thermodenitrificans NG80-2, Geobacillus thermodenitrificans str. NG80-2, Geobacillus thermodenitrificans strain NG80-2
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