node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
Msm_0122 | Msm_0123 | Msm_0122 | Msm_0123 | Predicted ATPase; COG0433. | Uncharacterized protein conserved in archaea; COG1630. | 0.966 |
Msm_0122 | Msm_0124 | Msm_0122 | Msm_0124 | Predicted ATPase; COG0433. | Predicted phosphate-binding protein (PcrB family); Prenyltransferase that catalyzes the transfer of the geranylgeranyl moiety of geranylgeranyl diphosphate (GGPP) to the C3 hydroxyl of sn-glycerol-1-phosphate (G1P). This reaction is the first ether-bond-formation step in the biosynthesis of archaeal membrane lipids. | 0.572 |
Msm_0123 | Msm_0122 | Msm_0123 | Msm_0122 | Uncharacterized protein conserved in archaea; COG1630. | Predicted ATPase; COG0433. | 0.966 |
Msm_0123 | Msm_0124 | Msm_0123 | Msm_0124 | Uncharacterized protein conserved in archaea; COG1630. | Predicted phosphate-binding protein (PcrB family); Prenyltransferase that catalyzes the transfer of the geranylgeranyl moiety of geranylgeranyl diphosphate (GGPP) to the C3 hydroxyl of sn-glycerol-1-phosphate (G1P). This reaction is the first ether-bond-formation step in the biosynthesis of archaeal membrane lipids. | 0.606 |
Msm_0124 | Msm_0122 | Msm_0124 | Msm_0122 | Predicted phosphate-binding protein (PcrB family); Prenyltransferase that catalyzes the transfer of the geranylgeranyl moiety of geranylgeranyl diphosphate (GGPP) to the C3 hydroxyl of sn-glycerol-1-phosphate (G1P). This reaction is the first ether-bond-formation step in the biosynthesis of archaeal membrane lipids. | Predicted ATPase; COG0433. | 0.572 |
Msm_0124 | Msm_0123 | Msm_0124 | Msm_0123 | Predicted phosphate-binding protein (PcrB family); Prenyltransferase that catalyzes the transfer of the geranylgeranyl moiety of geranylgeranyl diphosphate (GGPP) to the C3 hydroxyl of sn-glycerol-1-phosphate (G1P). This reaction is the first ether-bond-formation step in the biosynthesis of archaeal membrane lipids. | Uncharacterized protein conserved in archaea; COG1630. | 0.606 |
Msm_0124 | Msm_0126 | Msm_0124 | Msm_0126 | Predicted phosphate-binding protein (PcrB family); Prenyltransferase that catalyzes the transfer of the geranylgeranyl moiety of geranylgeranyl diphosphate (GGPP) to the C3 hydroxyl of sn-glycerol-1-phosphate (G1P). This reaction is the first ether-bond-formation step in the biosynthesis of archaeal membrane lipids. | Conserved hypothetical protein Msm_0126; Probable pre-rRNA processing protein involved in ribosome biogenesis; Belongs to the TSR3 family. | 0.498 |
Msm_0124 | Msm_0941 | Msm_0124 | Msm_0941 | Predicted phosphate-binding protein (PcrB family); Prenyltransferase that catalyzes the transfer of the geranylgeranyl moiety of geranylgeranyl diphosphate (GGPP) to the C3 hydroxyl of sn-glycerol-1-phosphate (G1P). This reaction is the first ether-bond-formation step in the biosynthesis of archaeal membrane lipids. | Prenyltransferase, UbiA; Prenyltransferase that catalyzes the transfer of the geranylgeranyl moiety of geranylgeranyl diphosphate (GGPP) to the C2 hydroxyl of (S)-3-O-geranylgeranylglyceryl phosphate (GGGP). This reaction is the second ether-bond-formation step in the biosynthesis of archaeal membrane lipids. | 0.988 |
Msm_0124 | carS | Msm_0124 | Msm_0850 | Predicted phosphate-binding protein (PcrB family); Prenyltransferase that catalyzes the transfer of the geranylgeranyl moiety of geranylgeranyl diphosphate (GGPP) to the C3 hydroxyl of sn-glycerol-1-phosphate (G1P). This reaction is the first ether-bond-formation step in the biosynthesis of archaeal membrane lipids. | Predicted CDP-diglyceride synthetase; Catalyzes the formation of CDP-2,3-bis-(O-geranylgeranyl)-sn- glycerol (CDP-archaeol) from 2,3-bis-(O-geranylgeranyl)-sn-glycerol 1- phosphate (DGGGP) and CTP. This reaction is the third ether-bond- formation step in the biosynthesis of archaeal membrane lipids. | 0.582 |
Msm_0124 | egsA | Msm_0124 | Msm_0286 | Predicted phosphate-binding protein (PcrB family); Prenyltransferase that catalyzes the transfer of the geranylgeranyl moiety of geranylgeranyl diphosphate (GGPP) to the C3 hydroxyl of sn-glycerol-1-phosphate (G1P). This reaction is the first ether-bond-formation step in the biosynthesis of archaeal membrane lipids. | Glycerol 1-phosphate dehydrogenase (Dehydroquinate synthase-like family); Catalyzes the NAD(P)H-dependent reduction of dihydroxyacetonephosphate (DHAP or glycerone phosphate) to glycerol 1- phosphate (G1P). The G1P thus generated is used as the glycerophosphate backbone of phospholipids in the cellular membranes of Archaea. | 0.954 |
Msm_0124 | gatA | Msm_0124 | Msm_1253 | Predicted phosphate-binding protein (PcrB family); Prenyltransferase that catalyzes the transfer of the geranylgeranyl moiety of geranylgeranyl diphosphate (GGPP) to the C3 hydroxyl of sn-glycerol-1-phosphate (G1P). This reaction is the first ether-bond-formation step in the biosynthesis of archaeal membrane lipids. | glutamyl-tRNA (Gln) amidotransferase subunit A, GatA; Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in organisms which lack glutaminyl-tRNA synthetase. The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu- tRNA(Gln). | 0.476 |
Msm_0124 | gatB | Msm_0124 | Msm_1101 | Predicted phosphate-binding protein (PcrB family); Prenyltransferase that catalyzes the transfer of the geranylgeranyl moiety of geranylgeranyl diphosphate (GGPP) to the C3 hydroxyl of sn-glycerol-1-phosphate (G1P). This reaction is the first ether-bond-formation step in the biosynthesis of archaeal membrane lipids. | Asp-tRNA(Asn)/Glu-tRNA(Gln) amidotransferase, B subunit, GatB; Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp-tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl- tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp- tRNA(Asn) or phospho-Glu-tRNA(Gln); Belongs to the GatB/GatE family. GatB subfamily. | 0.460 |
Msm_0124 | rpl40e | Msm_0124 | Msm_0125 | Predicted phosphate-binding protein (PcrB family); Prenyltransferase that catalyzes the transfer of the geranylgeranyl moiety of geranylgeranyl diphosphate (GGPP) to the C3 hydroxyl of sn-glycerol-1-phosphate (G1P). This reaction is the first ether-bond-formation step in the biosynthesis of archaeal membrane lipids. | Ribosomal protein L40e; COG1552; Belongs to the eukaryotic ribosomal protein eL40 family. | 0.623 |
Msm_0124 | tpiA | Msm_0124 | Msm_0919 | Predicted phosphate-binding protein (PcrB family); Prenyltransferase that catalyzes the transfer of the geranylgeranyl moiety of geranylgeranyl diphosphate (GGPP) to the C3 hydroxyl of sn-glycerol-1-phosphate (G1P). This reaction is the first ether-bond-formation step in the biosynthesis of archaeal membrane lipids. | Triosephosphate isomerase, TpiA; Involved in the gluconeogenesis. Catalyzes stereospecifically the conversion of dihydroxyacetone phosphate (DHAP) to D- glyceraldehyde-3-phosphate (G3P); Belongs to the triosephosphate isomerase family. | 0.705 |
Msm_0126 | Msm_0124 | Msm_0126 | Msm_0124 | Conserved hypothetical protein Msm_0126; Probable pre-rRNA processing protein involved in ribosome biogenesis; Belongs to the TSR3 family. | Predicted phosphate-binding protein (PcrB family); Prenyltransferase that catalyzes the transfer of the geranylgeranyl moiety of geranylgeranyl diphosphate (GGPP) to the C3 hydroxyl of sn-glycerol-1-phosphate (G1P). This reaction is the first ether-bond-formation step in the biosynthesis of archaeal membrane lipids. | 0.498 |
Msm_0126 | rpl40e | Msm_0126 | Msm_0125 | Conserved hypothetical protein Msm_0126; Probable pre-rRNA processing protein involved in ribosome biogenesis; Belongs to the TSR3 family. | Ribosomal protein L40e; COG1552; Belongs to the eukaryotic ribosomal protein eL40 family. | 0.769 |
Msm_0941 | Msm_0124 | Msm_0941 | Msm_0124 | Prenyltransferase, UbiA; Prenyltransferase that catalyzes the transfer of the geranylgeranyl moiety of geranylgeranyl diphosphate (GGPP) to the C2 hydroxyl of (S)-3-O-geranylgeranylglyceryl phosphate (GGGP). This reaction is the second ether-bond-formation step in the biosynthesis of archaeal membrane lipids. | Predicted phosphate-binding protein (PcrB family); Prenyltransferase that catalyzes the transfer of the geranylgeranyl moiety of geranylgeranyl diphosphate (GGPP) to the C3 hydroxyl of sn-glycerol-1-phosphate (G1P). This reaction is the first ether-bond-formation step in the biosynthesis of archaeal membrane lipids. | 0.988 |
Msm_0941 | carS | Msm_0941 | Msm_0850 | Prenyltransferase, UbiA; Prenyltransferase that catalyzes the transfer of the geranylgeranyl moiety of geranylgeranyl diphosphate (GGPP) to the C2 hydroxyl of (S)-3-O-geranylgeranylglyceryl phosphate (GGGP). This reaction is the second ether-bond-formation step in the biosynthesis of archaeal membrane lipids. | Predicted CDP-diglyceride synthetase; Catalyzes the formation of CDP-2,3-bis-(O-geranylgeranyl)-sn- glycerol (CDP-archaeol) from 2,3-bis-(O-geranylgeranyl)-sn-glycerol 1- phosphate (DGGGP) and CTP. This reaction is the third ether-bond- formation step in the biosynthesis of archaeal membrane lipids. | 0.971 |
Msm_0941 | egsA | Msm_0941 | Msm_0286 | Prenyltransferase, UbiA; Prenyltransferase that catalyzes the transfer of the geranylgeranyl moiety of geranylgeranyl diphosphate (GGPP) to the C2 hydroxyl of (S)-3-O-geranylgeranylglyceryl phosphate (GGGP). This reaction is the second ether-bond-formation step in the biosynthesis of archaeal membrane lipids. | Glycerol 1-phosphate dehydrogenase (Dehydroquinate synthase-like family); Catalyzes the NAD(P)H-dependent reduction of dihydroxyacetonephosphate (DHAP or glycerone phosphate) to glycerol 1- phosphate (G1P). The G1P thus generated is used as the glycerophosphate backbone of phospholipids in the cellular membranes of Archaea. | 0.773 |
Msm_0941 | tpiA | Msm_0941 | Msm_0919 | Prenyltransferase, UbiA; Prenyltransferase that catalyzes the transfer of the geranylgeranyl moiety of geranylgeranyl diphosphate (GGPP) to the C2 hydroxyl of (S)-3-O-geranylgeranylglyceryl phosphate (GGGP). This reaction is the second ether-bond-formation step in the biosynthesis of archaeal membrane lipids. | Triosephosphate isomerase, TpiA; Involved in the gluconeogenesis. Catalyzes stereospecifically the conversion of dihydroxyacetone phosphate (DHAP) to D- glyceraldehyde-3-phosphate (G3P); Belongs to the triosephosphate isomerase family. | 0.554 |