node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
Msm_1040 | purM | Msm_1040 | Msm_1039 | malate/L-lactate dehydrogenase; COG2055. | Phosphoribosylformylglycinamidine cyclo-ligase (AIRS), PurM; COG0150. | 0.835 |
Msm_1151 | purC | Msm_1151 | Msm_1547 | Adenylosuccinate lyase, PurB; COG0015; Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily. | Phosphoribosylaminoimidazole-succinocarboxamide (SAICAR) synthase, PurC; COG0152; Belongs to the SAICAR synthetase family. | 0.999 |
Msm_1151 | purD | Msm_1151 | Msm_1227 | Adenylosuccinate lyase, PurB; COG0015; Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily. | Phosphoribosylamine-glycine ligase, PurD; COG0151. | 0.998 |
Msm_1151 | purE | Msm_1151 | Msm_1287 | Adenylosuccinate lyase, PurB; COG0015; Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily. | Phosphoribosylaminoimidazole carboxylase (NCAIR mutase), PurE; Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR). | 0.999 |
Msm_1151 | purF | Msm_1151 | Msm_1704 | Adenylosuccinate lyase, PurB; COG0015; Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily. | Glutamine phosphoribosylpyrophosphate amidotransferase, PurF; Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine. | 0.999 |
Msm_1151 | purL | Msm_1151 | Msm_1342 | Adenylosuccinate lyase, PurB; COG0015; Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily. | Phosphoribosylformylglycinamidine (FGAM) synthase, PurL; Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP- dependent manner. PurS interacts with PurQ and PurL and is thought [...] | 0.998 |
Msm_1151 | purM | Msm_1151 | Msm_1039 | Adenylosuccinate lyase, PurB; COG0015; Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily. | Phosphoribosylformylglycinamidine cyclo-ligase (AIRS), PurM; COG0150. | 0.989 |
Msm_1151 | purQ | Msm_1151 | Msm_1549 | Adenylosuccinate lyase, PurB; COG0015; Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily. | Phosphoribosylformylglycinamidine (FGAM) synthase, PurQ; Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP- dependent manner. PurS interacts with PurQ and PurL and is thought [...] | 0.987 |
Msm_1151 | purS | Msm_1151 | Msm_1548 | Adenylosuccinate lyase, PurB; COG0015; Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily. | Phosphoribosylformylglycinamidine (FGAM) synthase, PurS; Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP- dependent manner. PurS interacts with PurQ and PurL and is thought [...] | 0.979 |
purC | Msm_1151 | Msm_1547 | Msm_1151 | Phosphoribosylaminoimidazole-succinocarboxamide (SAICAR) synthase, PurC; COG0152; Belongs to the SAICAR synthetase family. | Adenylosuccinate lyase, PurB; COG0015; Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily. | 0.999 |
purC | purD | Msm_1547 | Msm_1227 | Phosphoribosylaminoimidazole-succinocarboxamide (SAICAR) synthase, PurC; COG0152; Belongs to the SAICAR synthetase family. | Phosphoribosylamine-glycine ligase, PurD; COG0151. | 0.999 |
purC | purE | Msm_1547 | Msm_1287 | Phosphoribosylaminoimidazole-succinocarboxamide (SAICAR) synthase, PurC; COG0152; Belongs to the SAICAR synthetase family. | Phosphoribosylaminoimidazole carboxylase (NCAIR mutase), PurE; Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR). | 0.999 |
purC | purF | Msm_1547 | Msm_1704 | Phosphoribosylaminoimidazole-succinocarboxamide (SAICAR) synthase, PurC; COG0152; Belongs to the SAICAR synthetase family. | Glutamine phosphoribosylpyrophosphate amidotransferase, PurF; Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine. | 0.999 |
purC | purL | Msm_1547 | Msm_1342 | Phosphoribosylaminoimidazole-succinocarboxamide (SAICAR) synthase, PurC; COG0152; Belongs to the SAICAR synthetase family. | Phosphoribosylformylglycinamidine (FGAM) synthase, PurL; Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP- dependent manner. PurS interacts with PurQ and PurL and is thought [...] | 0.999 |
purC | purM | Msm_1547 | Msm_1039 | Phosphoribosylaminoimidazole-succinocarboxamide (SAICAR) synthase, PurC; COG0152; Belongs to the SAICAR synthetase family. | Phosphoribosylformylglycinamidine cyclo-ligase (AIRS), PurM; COG0150. | 0.999 |
purC | purQ | Msm_1547 | Msm_1549 | Phosphoribosylaminoimidazole-succinocarboxamide (SAICAR) synthase, PurC; COG0152; Belongs to the SAICAR synthetase family. | Phosphoribosylformylglycinamidine (FGAM) synthase, PurQ; Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP- dependent manner. PurS interacts with PurQ and PurL and is thought [...] | 0.999 |
purC | purS | Msm_1547 | Msm_1548 | Phosphoribosylaminoimidazole-succinocarboxamide (SAICAR) synthase, PurC; COG0152; Belongs to the SAICAR synthetase family. | Phosphoribosylformylglycinamidine (FGAM) synthase, PurS; Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP- dependent manner. PurS interacts with PurQ and PurL and is thought [...] | 0.999 |
purD | Msm_1151 | Msm_1227 | Msm_1151 | Phosphoribosylamine-glycine ligase, PurD; COG0151. | Adenylosuccinate lyase, PurB; COG0015; Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily. | 0.998 |
purD | purC | Msm_1227 | Msm_1547 | Phosphoribosylamine-glycine ligase, PurD; COG0151. | Phosphoribosylaminoimidazole-succinocarboxamide (SAICAR) synthase, PurC; COG0152; Belongs to the SAICAR synthetase family. | 0.999 |
purD | purE | Msm_1227 | Msm_1287 | Phosphoribosylamine-glycine ligase, PurD; COG0151. | Phosphoribosylaminoimidazole carboxylase (NCAIR mutase), PurE; Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR). | 0.999 |