node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
Mpe_A0159 | Mpe_A0207 | Mpe_A0159 | Mpe_A0207 | Malate synthase; Belongs to the malate synthase family. | Malate dehydrogenase (NADP+); Oxaloacetate decarboxylating protein; phosphate acetyltransferase; Belongs to the malic enzymes family. | 0.979 |
Mpe_A0159 | Mpe_A1382 | Mpe_A0159 | Mpe_A1382 | Malate synthase; Belongs to the malate synthase family. | Fumarase; Catalyzes the reversible hydration of fumarate to (S)-malate. Belongs to the class-I fumarase family. | 0.939 |
Mpe_A0159 | Mpe_A2165 | Mpe_A0159 | Mpe_A2165 | Malate synthase; Belongs to the malate synthase family. | Citrate synthase; Belongs to the citrate synthase family. | 0.968 |
Mpe_A0159 | Mpe_A2468 | Mpe_A0159 | Mpe_A2468 | Malate synthase; Belongs to the malate synthase family. | Isocitrate dehydrogenase (NADP). | 0.611 |
Mpe_A0159 | fumC | Mpe_A0159 | Mpe_A3332 | Malate synthase; Belongs to the malate synthase family. | Fumarase; Involved in the TCA cycle. Catalyzes the stereospecific interconversion of fumarate to L-malate; Belongs to the class-II fumarase/aspartase family. Fumarase subfamily. | 0.932 |
Mpe_A0159 | mdh | Mpe_A0159 | Mpe_A2172 | Malate synthase; Belongs to the malate synthase family. | Malate dehydrogenase (NAD); Catalyzes the reversible oxidation of malate to oxaloacetate. Belongs to the LDH/MDH superfamily. MDH type 2 family. | 0.939 |
Mpe_A0159 | pckG | Mpe_A0159 | Mpe_A3705 | Malate synthase; Belongs to the malate synthase family. | Phosphoenolpyruvate carboxykinase (GTP); Catalyzes the conversion of oxaloacetate (OAA) to phosphoenolpyruvate (PEP), the rate-limiting step in the metabolic pathway that produces glucose from lactate and other precursors derived from the citric acid cycle; Belongs to the phosphoenolpyruvate carboxykinase [GTP] family. | 0.841 |
Mpe_A0159 | ppc | Mpe_A0159 | Mpe_A3003 | Malate synthase; Belongs to the malate synthase family. | Phosphoenolpyruvate carboxylase; Forms oxaloacetate, a four-carbon dicarboxylic acid source for the tricarboxylic acid cycle; Belongs to the PEPCase type 1 family. | 0.834 |
Mpe_A0159 | sucC-2 | Mpe_A0159 | Mpe_A3257 | Malate synthase; Belongs to the malate synthase family. | succinyl-CoA synthetase (ADP-forming) beta subunit; Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The beta subunit provides nucleotide specificity of the enzyme and binds the substrate succinate, while the binding sites for coenzyme A and phosphate are found in the alpha subunit. | 0.911 |
Mpe_A0159 | sucD-2 | Mpe_A0159 | Mpe_A3256 | Malate synthase; Belongs to the malate synthase family. | succinyl-CoA synthetase (ADP-forming) alpha subunit; Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit. | 0.917 |
Mpe_A0207 | Mpe_A0159 | Mpe_A0207 | Mpe_A0159 | Malate dehydrogenase (NADP+); Oxaloacetate decarboxylating protein; phosphate acetyltransferase; Belongs to the malic enzymes family. | Malate synthase; Belongs to the malate synthase family. | 0.979 |
Mpe_A0207 | Mpe_A1382 | Mpe_A0207 | Mpe_A1382 | Malate dehydrogenase (NADP+); Oxaloacetate decarboxylating protein; phosphate acetyltransferase; Belongs to the malic enzymes family. | Fumarase; Catalyzes the reversible hydration of fumarate to (S)-malate. Belongs to the class-I fumarase family. | 0.972 |
Mpe_A0207 | Mpe_A2165 | Mpe_A0207 | Mpe_A2165 | Malate dehydrogenase (NADP+); Oxaloacetate decarboxylating protein; phosphate acetyltransferase; Belongs to the malic enzymes family. | Citrate synthase; Belongs to the citrate synthase family. | 0.942 |
Mpe_A0207 | Mpe_A2468 | Mpe_A0207 | Mpe_A2468 | Malate dehydrogenase (NADP+); Oxaloacetate decarboxylating protein; phosphate acetyltransferase; Belongs to the malic enzymes family. | Isocitrate dehydrogenase (NADP). | 0.564 |
Mpe_A0207 | fumC | Mpe_A0207 | Mpe_A3332 | Malate dehydrogenase (NADP+); Oxaloacetate decarboxylating protein; phosphate acetyltransferase; Belongs to the malic enzymes family. | Fumarase; Involved in the TCA cycle. Catalyzes the stereospecific interconversion of fumarate to L-malate; Belongs to the class-II fumarase/aspartase family. Fumarase subfamily. | 0.971 |
Mpe_A0207 | mdh | Mpe_A0207 | Mpe_A2172 | Malate dehydrogenase (NADP+); Oxaloacetate decarboxylating protein; phosphate acetyltransferase; Belongs to the malic enzymes family. | Malate dehydrogenase (NAD); Catalyzes the reversible oxidation of malate to oxaloacetate. Belongs to the LDH/MDH superfamily. MDH type 2 family. | 0.971 |
Mpe_A0207 | pckG | Mpe_A0207 | Mpe_A3705 | Malate dehydrogenase (NADP+); Oxaloacetate decarboxylating protein; phosphate acetyltransferase; Belongs to the malic enzymes family. | Phosphoenolpyruvate carboxykinase (GTP); Catalyzes the conversion of oxaloacetate (OAA) to phosphoenolpyruvate (PEP), the rate-limiting step in the metabolic pathway that produces glucose from lactate and other precursors derived from the citric acid cycle; Belongs to the phosphoenolpyruvate carboxykinase [GTP] family. | 0.455 |
Mpe_A0207 | ppc | Mpe_A0207 | Mpe_A3003 | Malate dehydrogenase (NADP+); Oxaloacetate decarboxylating protein; phosphate acetyltransferase; Belongs to the malic enzymes family. | Phosphoenolpyruvate carboxylase; Forms oxaloacetate, a four-carbon dicarboxylic acid source for the tricarboxylic acid cycle; Belongs to the PEPCase type 1 family. | 0.426 |
Mpe_A0207 | sucC-2 | Mpe_A0207 | Mpe_A3257 | Malate dehydrogenase (NADP+); Oxaloacetate decarboxylating protein; phosphate acetyltransferase; Belongs to the malic enzymes family. | succinyl-CoA synthetase (ADP-forming) beta subunit; Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The beta subunit provides nucleotide specificity of the enzyme and binds the substrate succinate, while the binding sites for coenzyme A and phosphate are found in the alpha subunit. | 0.927 |
Mpe_A0207 | sucD-2 | Mpe_A0207 | Mpe_A3256 | Malate dehydrogenase (NADP+); Oxaloacetate decarboxylating protein; phosphate acetyltransferase; Belongs to the malic enzymes family. | succinyl-CoA synthetase (ADP-forming) alpha subunit; Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit. | 0.903 |