STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
Mpe_A2267Acetaldehyde dehydrogenase; Catalyzes the conversion of acetaldehyde to acetyl-CoA, using NAD(+) and coenzyme A. Is the final enzyme in the meta-cleavage pathway for the degradation of aromatic compounds. (303 aa)    
Predicted Functional Partners:
Mpe_A2266
4-hydroxy 2-oxovalerate aldolase; Catalyzes the retro-aldol cleavage of 4-hydroxy-2- oxopentanoate to pyruvate and acetaldehyde. Is involved in the meta- cleavage pathway for the degradation of aromatic compounds. Belongs to the 4-hydroxy-2-oxovalerate aldolase family.
 
 0.997
Mpe_A3321
4-hydroxy 2-oxovalerate aldolase; Catalyzes the retro-aldol cleavage of 4-hydroxy-2- oxopentanoate to pyruvate and acetaldehyde. Is involved in the meta- cleavage pathway for the degradation of aromatic compounds. Belongs to the 4-hydroxy-2-oxovalerate aldolase family.
 
 0.992
leuA
2-isopropylmalate synthase; Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3- hydroxy-4-methylpentanoate (2-isopropylmalate); Belongs to the alpha-IPM synthase/homocitrate synthase family. LeuA type 1 subfamily.
  
 0.970
Mpe_A1600
Acetoin dehydrogenase complex, E2 component, dihydrolipoamide acetyltransferase.
  
 
 0.908
Mpe_A0599
Aldehyde dehydrogenase (NAD+); Belongs to the aldehyde dehydrogenase family.
    
 0.905
Mpe_A2577
Aldehyde dehydrogenase.
    
 0.905
Mpe_A0416
Acetyl-CoA C-acyltransferase; Belongs to the thiolase-like superfamily. Thiolase family.
     
 0.903
Mpe_A0879
Acetyl-CoA C-acyltransferase; Belongs to the thiolase-like superfamily. Thiolase family.
     
 0.903
Mpe_A1536
Acetyl-CoA C-acetyltransferase; Belongs to the thiolase-like superfamily. Thiolase family.
     
 0.903
Mpe_A1776
Acetyl-CoA C-acetyltransferase; Belongs to the thiolase-like superfamily. Thiolase family.
     
 0.903
Your Current Organism:
Methylibium petroleiphilum
NCBI taxonomy Id: 420662
Other names: M. petroleiphilum PM1, MTBE-degrading bacterium PM1, Methylibium petroleiphilum PM1, Methylibium petroleiphilum str. PM1, Methylibium petroleiphilum strain PM1, Rubrivivax gelatinosus PM1
Server load: medium (46%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.