node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
Mpe_A2140 | Mpe_A3809 | Mpe_A2140 | Mpe_A3809 | Putative 3-deoxy-D-manno-octulosonic-acid transferase transmembrane protein, gene; Involved in lipopolysaccharide (LPS) biosynthesis. Catalyzes the transfer of 3-deoxy-D-manno-octulosonate (Kdo) residue(s) from CMP- Kdo to lipid IV(A), the tetraacyldisaccharide-1,4'-bisphosphate precursor of lipid A; Belongs to the glycosyltransferase group 1 family. | Arabinose-5-phosphate isomerase; Belongs to the SIS family. GutQ/KpsF subfamily. | 0.884 |
Mpe_A2140 | kdsA | Mpe_A2140 | Mpe_A2846 | Putative 3-deoxy-D-manno-octulosonic-acid transferase transmembrane protein, gene; Involved in lipopolysaccharide (LPS) biosynthesis. Catalyzes the transfer of 3-deoxy-D-manno-octulosonate (Kdo) residue(s) from CMP- Kdo to lipid IV(A), the tetraacyldisaccharide-1,4'-bisphosphate precursor of lipid A; Belongs to the glycosyltransferase group 1 family. | Putative 2-dehydro-3-deoxyphosphooctonate aldolase; Belongs to the KdsA family. | 0.853 |
Mpe_A2140 | kdsB | Mpe_A2140 | Mpe_A2487 | Putative 3-deoxy-D-manno-octulosonic-acid transferase transmembrane protein, gene; Involved in lipopolysaccharide (LPS) biosynthesis. Catalyzes the transfer of 3-deoxy-D-manno-octulosonate (Kdo) residue(s) from CMP- Kdo to lipid IV(A), the tetraacyldisaccharide-1,4'-bisphosphate precursor of lipid A; Belongs to the glycosyltransferase group 1 family. | 3-deoxy-manno-octulosonate cytidylyltransferase; Activates KDO (a required 8-carbon sugar) for incorporation into bacterial lipopolysaccharide in Gram-negative bacteria. | 0.985 |
Mpe_A2140 | lpxA | Mpe_A2140 | Mpe_A1968 | Putative 3-deoxy-D-manno-octulosonic-acid transferase transmembrane protein, gene; Involved in lipopolysaccharide (LPS) biosynthesis. Catalyzes the transfer of 3-deoxy-D-manno-octulosonate (Kdo) residue(s) from CMP- Kdo to lipid IV(A), the tetraacyldisaccharide-1,4'-bisphosphate precursor of lipid A; Belongs to the glycosyltransferase group 1 family. | acyl-[acyl-carrier-protein]--UDP-N- acetylglucosamine O-acyltransferase; Involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell. | 0.855 |
Mpe_A2140 | lpxB | Mpe_A2140 | Mpe_A1967 | Putative 3-deoxy-D-manno-octulosonic-acid transferase transmembrane protein, gene; Involved in lipopolysaccharide (LPS) biosynthesis. Catalyzes the transfer of 3-deoxy-D-manno-octulosonate (Kdo) residue(s) from CMP- Kdo to lipid IV(A), the tetraacyldisaccharide-1,4'-bisphosphate precursor of lipid A; Belongs to the glycosyltransferase group 1 family. | lipid-A-disaccharide synthase; Condensation of UDP-2,3-diacylglucosamine and 2,3- diacylglucosamine-1-phosphate to form lipid A disaccharide, a precursor of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell. | 0.859 |
Mpe_A2140 | lpxC | Mpe_A2140 | Mpe_A0468 | Putative 3-deoxy-D-manno-octulosonic-acid transferase transmembrane protein, gene; Involved in lipopolysaccharide (LPS) biosynthesis. Catalyzes the transfer of 3-deoxy-D-manno-octulosonate (Kdo) residue(s) from CMP- Kdo to lipid IV(A), the tetraacyldisaccharide-1,4'-bisphosphate precursor of lipid A; Belongs to the glycosyltransferase group 1 family. | UDP-3-O-[3-hydroxymyristoyl] N-acetylglucosamine deacetylase; Catalyzes the hydrolysis of UDP-3-O-myristoyl-N- acetylglucosamine to form UDP-3-O-myristoylglucosamine and acetate, the committed step in lipid A biosynthesis; Belongs to the LpxC family. | 0.857 |
Mpe_A2140 | lpxD | Mpe_A2140 | Mpe_A1969 | Putative 3-deoxy-D-manno-octulosonic-acid transferase transmembrane protein, gene; Involved in lipopolysaccharide (LPS) biosynthesis. Catalyzes the transfer of 3-deoxy-D-manno-octulosonate (Kdo) residue(s) from CMP- Kdo to lipid IV(A), the tetraacyldisaccharide-1,4'-bisphosphate precursor of lipid A; Belongs to the glycosyltransferase group 1 family. | UDP-3-O-[3-hydroxymyristoyl] glucosamine N-acyltransferase; Catalyzes the N-acylation of UDP-3-O-acylglucosamine using 3- hydroxyacyl-ACP as the acyl donor. Is involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell. Belongs to the transferase hexapeptide repeat family. LpxD subfamily. | 0.856 |
Mpe_A2140 | lpxK | Mpe_A2140 | Mpe_A2485 | Putative 3-deoxy-D-manno-octulosonic-acid transferase transmembrane protein, gene; Involved in lipopolysaccharide (LPS) biosynthesis. Catalyzes the transfer of 3-deoxy-D-manno-octulosonate (Kdo) residue(s) from CMP- Kdo to lipid IV(A), the tetraacyldisaccharide-1,4'-bisphosphate precursor of lipid A; Belongs to the glycosyltransferase group 1 family. | lipid-A-disaccharide synthase; Transfers the gamma-phosphate of ATP to the 4'-position of a tetraacyldisaccharide 1-phosphate intermediate (termed DS-1-P) to form tetraacyldisaccharide 1,4'-bis-phosphate (lipid IVA). | 0.992 |
Mpe_A2484 | Mpe_A2486 | Mpe_A2484 | Mpe_A2486 | Putative biopolymer transport exbD-related transmembrane protein. | Conserved hypothetical protein; Belongs to the UPF0434 family. | 0.800 |
Mpe_A2484 | kdsB | Mpe_A2484 | Mpe_A2487 | Putative biopolymer transport exbD-related transmembrane protein. | 3-deoxy-manno-octulosonate cytidylyltransferase; Activates KDO (a required 8-carbon sugar) for incorporation into bacterial lipopolysaccharide in Gram-negative bacteria. | 0.858 |
Mpe_A2484 | lpxA | Mpe_A2484 | Mpe_A1968 | Putative biopolymer transport exbD-related transmembrane protein. | acyl-[acyl-carrier-protein]--UDP-N- acetylglucosamine O-acyltransferase; Involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell. | 0.456 |
Mpe_A2484 | lpxK | Mpe_A2484 | Mpe_A2485 | Putative biopolymer transport exbD-related transmembrane protein. | lipid-A-disaccharide synthase; Transfers the gamma-phosphate of ATP to the 4'-position of a tetraacyldisaccharide 1-phosphate intermediate (termed DS-1-P) to form tetraacyldisaccharide 1,4'-bis-phosphate (lipid IVA). | 0.835 |
Mpe_A2486 | Mpe_A2484 | Mpe_A2486 | Mpe_A2484 | Conserved hypothetical protein; Belongs to the UPF0434 family. | Putative biopolymer transport exbD-related transmembrane protein. | 0.800 |
Mpe_A2486 | kdsB | Mpe_A2486 | Mpe_A2487 | Conserved hypothetical protein; Belongs to the UPF0434 family. | 3-deoxy-manno-octulosonate cytidylyltransferase; Activates KDO (a required 8-carbon sugar) for incorporation into bacterial lipopolysaccharide in Gram-negative bacteria. | 0.867 |
Mpe_A2486 | lpxK | Mpe_A2486 | Mpe_A2485 | Conserved hypothetical protein; Belongs to the UPF0434 family. | lipid-A-disaccharide synthase; Transfers the gamma-phosphate of ATP to the 4'-position of a tetraacyldisaccharide 1-phosphate intermediate (termed DS-1-P) to form tetraacyldisaccharide 1,4'-bis-phosphate (lipid IVA). | 0.836 |
Mpe_A3809 | Mpe_A2140 | Mpe_A3809 | Mpe_A2140 | Arabinose-5-phosphate isomerase; Belongs to the SIS family. GutQ/KpsF subfamily. | Putative 3-deoxy-D-manno-octulosonic-acid transferase transmembrane protein, gene; Involved in lipopolysaccharide (LPS) biosynthesis. Catalyzes the transfer of 3-deoxy-D-manno-octulosonate (Kdo) residue(s) from CMP- Kdo to lipid IV(A), the tetraacyldisaccharide-1,4'-bisphosphate precursor of lipid A; Belongs to the glycosyltransferase group 1 family. | 0.884 |
Mpe_A3809 | kdsA | Mpe_A3809 | Mpe_A2846 | Arabinose-5-phosphate isomerase; Belongs to the SIS family. GutQ/KpsF subfamily. | Putative 2-dehydro-3-deoxyphosphooctonate aldolase; Belongs to the KdsA family. | 0.989 |
Mpe_A3809 | kdsB | Mpe_A3809 | Mpe_A2487 | Arabinose-5-phosphate isomerase; Belongs to the SIS family. GutQ/KpsF subfamily. | 3-deoxy-manno-octulosonate cytidylyltransferase; Activates KDO (a required 8-carbon sugar) for incorporation into bacterial lipopolysaccharide in Gram-negative bacteria. | 0.889 |
Mpe_A3809 | lpxA | Mpe_A3809 | Mpe_A1968 | Arabinose-5-phosphate isomerase; Belongs to the SIS family. GutQ/KpsF subfamily. | acyl-[acyl-carrier-protein]--UDP-N- acetylglucosamine O-acyltransferase; Involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell. | 0.871 |
Mpe_A3809 | lpxB | Mpe_A3809 | Mpe_A1967 | Arabinose-5-phosphate isomerase; Belongs to the SIS family. GutQ/KpsF subfamily. | lipid-A-disaccharide synthase; Condensation of UDP-2,3-diacylglucosamine and 2,3- diacylglucosamine-1-phosphate to form lipid A disaccharide, a precursor of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell. | 0.875 |