node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
Mpe_A0589 | pdxH | Mpe_A0589 | Mpe_A2931 | Conserved hypothetical protein. | Pyridoxamine 5'-phosphate oxidase; Catalyzes the oxidation of either pyridoxine 5'-phosphate (PNP) or pyridoxamine 5'-phosphate (PMP) into pyridoxal 5'-phosphate (PLP). | 0.639 |
Mpe_A2929 | Mpe_A2930 | Mpe_A2929 | Mpe_A2930 | Putative dehydrogenase, large chain oxidoreductase protein. | Isoquinoline 1-oxidoreductase, alpha subunit. | 0.994 |
Mpe_A2929 | pdxH | Mpe_A2929 | Mpe_A2931 | Putative dehydrogenase, large chain oxidoreductase protein. | Pyridoxamine 5'-phosphate oxidase; Catalyzes the oxidation of either pyridoxine 5'-phosphate (PNP) or pyridoxamine 5'-phosphate (PMP) into pyridoxal 5'-phosphate (PLP). | 0.543 |
Mpe_A2930 | Mpe_A2929 | Mpe_A2930 | Mpe_A2929 | Isoquinoline 1-oxidoreductase, alpha subunit. | Putative dehydrogenase, large chain oxidoreductase protein. | 0.994 |
Mpe_A2930 | pdxH | Mpe_A2930 | Mpe_A2931 | Isoquinoline 1-oxidoreductase, alpha subunit. | Pyridoxamine 5'-phosphate oxidase; Catalyzes the oxidation of either pyridoxine 5'-phosphate (PNP) or pyridoxamine 5'-phosphate (PMP) into pyridoxal 5'-phosphate (PLP). | 0.547 |
carA | carB | Mpe_A1261 | Mpe_A1262 | Carbamoyl-phosphate synthase small subunit; Belongs to the CarA family. | Carbamoyl-phosphate synthase large subunit; Belongs to the CarB family. | 0.999 |
carA | pdxH | Mpe_A1261 | Mpe_A2931 | Carbamoyl-phosphate synthase small subunit; Belongs to the CarA family. | Pyridoxamine 5'-phosphate oxidase; Catalyzes the oxidation of either pyridoxine 5'-phosphate (PNP) or pyridoxamine 5'-phosphate (PMP) into pyridoxal 5'-phosphate (PLP). | 0.448 |
carA | pyrB | Mpe_A1261 | Mpe_A0708 | Carbamoyl-phosphate synthase small subunit; Belongs to the CarA family. | Aspartate carbamoyltransferase; Belongs to the aspartate/ornithine carbamoyltransferase superfamily. ATCase family. | 0.999 |
carB | carA | Mpe_A1262 | Mpe_A1261 | Carbamoyl-phosphate synthase large subunit; Belongs to the CarB family. | Carbamoyl-phosphate synthase small subunit; Belongs to the CarA family. | 0.999 |
carB | pdxH | Mpe_A1262 | Mpe_A2931 | Carbamoyl-phosphate synthase large subunit; Belongs to the CarB family. | Pyridoxamine 5'-phosphate oxidase; Catalyzes the oxidation of either pyridoxine 5'-phosphate (PNP) or pyridoxamine 5'-phosphate (PMP) into pyridoxal 5'-phosphate (PLP). | 0.440 |
carB | pyrB | Mpe_A1262 | Mpe_A0708 | Carbamoyl-phosphate synthase large subunit; Belongs to the CarB family. | Aspartate carbamoyltransferase; Belongs to the aspartate/ornithine carbamoyltransferase superfamily. ATCase family. | 0.999 |
gcvP | pdxH | Mpe_A1431 | Mpe_A2931 | Glycine dehydrogenase (decarboxylating); The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor; CO(2) is released and the remaining methylamine moiety is then transferred to the lipoamide cofactor of the H protein; Belongs to the GcvP family. | Pyridoxamine 5'-phosphate oxidase; Catalyzes the oxidation of either pyridoxine 5'-phosphate (PNP) or pyridoxamine 5'-phosphate (PMP) into pyridoxal 5'-phosphate (PLP). | 0.593 |
nnrD | pdxH | Mpe_A1982 | Mpe_A2931 | Conserved hypothetical protein; Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration. Catalyzes the epimerization of the S- and R-forms of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration. This is a prerequisite for the S-specific NAD(P)H-hydrate dehydratase to allow the repair o [...] | Pyridoxamine 5'-phosphate oxidase; Catalyzes the oxidation of either pyridoxine 5'-phosphate (PNP) or pyridoxamine 5'-phosphate (PMP) into pyridoxal 5'-phosphate (PLP). | 0.446 |
pdxH | Mpe_A0589 | Mpe_A2931 | Mpe_A0589 | Pyridoxamine 5'-phosphate oxidase; Catalyzes the oxidation of either pyridoxine 5'-phosphate (PNP) or pyridoxamine 5'-phosphate (PMP) into pyridoxal 5'-phosphate (PLP). | Conserved hypothetical protein. | 0.639 |
pdxH | Mpe_A2929 | Mpe_A2931 | Mpe_A2929 | Pyridoxamine 5'-phosphate oxidase; Catalyzes the oxidation of either pyridoxine 5'-phosphate (PNP) or pyridoxamine 5'-phosphate (PMP) into pyridoxal 5'-phosphate (PLP). | Putative dehydrogenase, large chain oxidoreductase protein. | 0.543 |
pdxH | Mpe_A2930 | Mpe_A2931 | Mpe_A2930 | Pyridoxamine 5'-phosphate oxidase; Catalyzes the oxidation of either pyridoxine 5'-phosphate (PNP) or pyridoxamine 5'-phosphate (PMP) into pyridoxal 5'-phosphate (PLP). | Isoquinoline 1-oxidoreductase, alpha subunit. | 0.547 |
pdxH | carA | Mpe_A2931 | Mpe_A1261 | Pyridoxamine 5'-phosphate oxidase; Catalyzes the oxidation of either pyridoxine 5'-phosphate (PNP) or pyridoxamine 5'-phosphate (PMP) into pyridoxal 5'-phosphate (PLP). | Carbamoyl-phosphate synthase small subunit; Belongs to the CarA family. | 0.448 |
pdxH | carB | Mpe_A2931 | Mpe_A1262 | Pyridoxamine 5'-phosphate oxidase; Catalyzes the oxidation of either pyridoxine 5'-phosphate (PNP) or pyridoxamine 5'-phosphate (PMP) into pyridoxal 5'-phosphate (PLP). | Carbamoyl-phosphate synthase large subunit; Belongs to the CarB family. | 0.440 |
pdxH | gcvP | Mpe_A2931 | Mpe_A1431 | Pyridoxamine 5'-phosphate oxidase; Catalyzes the oxidation of either pyridoxine 5'-phosphate (PNP) or pyridoxamine 5'-phosphate (PMP) into pyridoxal 5'-phosphate (PLP). | Glycine dehydrogenase (decarboxylating); The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor; CO(2) is released and the remaining methylamine moiety is then transferred to the lipoamide cofactor of the H protein; Belongs to the GcvP family. | 0.593 |
pdxH | nnrD | Mpe_A2931 | Mpe_A1982 | Pyridoxamine 5'-phosphate oxidase; Catalyzes the oxidation of either pyridoxine 5'-phosphate (PNP) or pyridoxamine 5'-phosphate (PMP) into pyridoxal 5'-phosphate (PLP). | Conserved hypothetical protein; Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration. Catalyzes the epimerization of the S- and R-forms of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration. This is a prerequisite for the S-specific NAD(P)H-hydrate dehydratase to allow the repair o [...] | 0.446 |